ACL_RS00030

Uniprot: A9NE68
Description: DNA repair protein RecF
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. {ECO:0000255|HAMAP-Rule:MF_00365}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding: NP_BIND 29 36 ATP. {ECO:0000255|HAMAP-Rule:MF_00365}.
Site:
Gene names (primary): recF
Gene names (synonym):
Mass: 40,524
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; ATP binding [GO:0005524]; single-stranded DNA binding [GO:0003697]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432]
Gene ontology IDs: GO:0003697; GO:0005524; GO:0005737; GO:0006260; GO:0006281; GO:0009432
Chain: CHAIN 1 349 DNA replication and repair protein RecF. /FTId=PRO_1000079579.
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the RecF family. {ECO:0000255|HAMAP-Rule:MF_00365}.
Protein families: RecF family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NE68
MEROPS:
EnsemblBacteria KO: ABX80648
UniPathway: K03629
CDD:
Gene3D:
HAMAP: 3.40.50.300
InterPro: MF_00365
PANTHER: IPR001238;IPR018078;IPR027417;IPR003395
PIRSF: PTHR32182:SF0
PRINTS:
PROSITE:
Pfam: PS00617;PS00618
ProDom: PF02463
SMART:
SUPFAM:
TIGRFAMs: SSF52540

4689-5739(+)

>nucleotide sequence
ATGATTACTTCAATTGAATTAAGAAACTTTAGAAATTTAGAAAATTATAAAGTTTTAATC
AATAAACCACTTGTGATTATTCAAGGCTTAAACGGAGTTGGAAAGACTTCCATTCTAGAA
TCGATTTATTTTGCTGCAACAACAAAGTCACATCGATCAAGCGTTGAAAAGGATATGATT
CAATATGATAAACCCTATGCCTCAGTAAAACTTATAGAGGATTCAAAACTACATGAGATT
GTACTTACACCAAATGGTAAAAGAACAACCATCAATAAATCAGAAGTTAGAAAAATTTCT
GACTATATAGGTCAATTAAGAGTTGTAATGTTTGCTCCTGAAGACTTAATGCTTATCAAG
GGAAGTCCTTCCGAGCGACGTTACTTTTTAGATATGGAACTCATGCAAGTTTCTAAAACC
TATTTAAGAAATTTAAATAGTTATAAAAAGATCTTAAAACAAAGAAATGCTTTACTTAAG
AAAAACAGAAATTTAACAGATTATACATTCTTAAATATTTTAGGTGAACAACTCTATGAT
GTAGGTATTCAAATTTTTGATGAAAGACAAAAGTTTATTGAAGCACTTAATCAAAAATTT
AAAACAATACAAACAAAGTATAAGGACTTTGAAGTTGAGATGCTATATGAACCTAACGTC
ACTAAAGAAAATTTCCTTAAACATCTTAAAACAAAACAAAAACAAGATATTATGTATGAG
ACAACAACTGCCGGTATACATAAAGACGACTTTAAACTACTTTATAAGGGTTTGAATGCA
AAAGACAGTGCATCACAGGGAACAAGTAGATTAATTGTCATAGAACTCAAATTAGCCTTG
TTAGAATGGATTAAAGAAGTAACTAAGACAGATGCAATCTTACTATTAGATGATGTATTA
TCTGAATTAGATTTAGAACGTCAAAACTTGTTTATGAGTCAACTATCTAAAAATCATCAA
GTATTTATTACAACAGCACTACCTATAAATGGACACATAGATTTTCAAAAAATAGTATTA
CAAGAAGGAGAAACAATCAATGCCAAATAA

>protein sequence
MITSIELRNFRNLENYKVLINKPLVIIQGLNGVGKTSILESIYFAATTKSHRSSVEKDMI
QYDKPYASVKLIEDSKLHEIVLTPNGKRTTINKSEVRKISDYIGQLRVVMFAPEDLMLIK
GSPSERRYFLDMELMQVSKTYLRNLNSYKKILKQRNALLKKNRNLTDYTFLNILGEQLYD
VGIQIFDERQKFIEALNQKFKTIQTKYKDFEVEMLYEPNVTKENFLKHLKTKQKQDIMYE
TTTAGIHKDDFKLLYKGLNAKDSASQGTSRLIVIELKLALLEWIKEVTKTDAILLLDDVL
SELDLERQNLFMSQLSKNHQVFITTALPINGHIDFQKIVLQEGETINAK