ACL_RS00145

Uniprot: A9NE91
Description: formate acetyltransferase
EC number: 2.3.1.54
Annotation score: 1 out of 5
Miscellaneous [CC]:
Protein existence: Predicted
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site: ACT_SITE 406 406 S-acetylcysteine intermediate. {ECO:0000256|PIRSR:PIRSR000379-1}.; ACT_SITE 407 407 Cysteine radical intermediate. {ECO:0000256|PIRSR:PIRSR000379-1}.
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): pfl
Gene names (synonym):
Mass: 84,721
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; formate C-acetyltransferase activity [GO:0008861]; lyase activity [GO:0016829]; carbohydrate metabolic process [GO:0005975]
Gene ontology IDs: GO:0005737; GO:0005975; GO:0008861; GO:0016829
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Contains glycine radical domain. {ECO:0000256|SAAS:SAAS00518908}.
Protein families:
Coiled coil:
Domain [FT]: DOMAIN 1 615 PFL. {ECO:0000259|PROSITE:PS51554}.; DOMAIN 622 756 Glycine radical. {ECO:0000259|PROSITE:PS51149}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NE91
MEROPS:
EnsemblBacteria KO: ABX80671
UniPathway: K00656
CDD:
Gene3D:
HAMAP:
InterPro:
PANTHER: IPR005949;IPR019777;IPR001150;IPR004184
PIRSF:
PRINTS: PIRSF000379
PROSITE:
Pfam: PS00850;PS51149;PS51554
ProDom: PF01228;PF02901
SMART:
SUPFAM:
TIGRFAMs:

32363-34634(+)

>nucleotide sequence
ATGGCTCAATCATGGAAAGGTTTTAAATCTGGTAACTGGGAAAAAGCAGTCGATGTTGCA
GATTTCATAAAACAAAACTATTCAGAGTATACAGGAGACGGCACTTTTTTAGAAGGTGCA
GTAGAAAGTTCTTTATCATTAAATGAATCTTTTAAAGATTTATTGAAACTTGAAAAAGAA
AAAGGTGGCGTAATTGATTTAGATACAAAGGTTGCATCTACAATCATTAGCCATGCGCCA
GGGTATATCGATAAAGATATCGAAAAAATTGTTGGTTTACAAACTGATGCACCATTAAAA
CGTGGATTCTTTCCTGAAGGTGGAATTAACGTTGCTGTAAAATCCGTTGAAGCTTATGGT
TATAAAGTAGAACAAGAAACAATTGATATTTATACAAACGTTAGAAAAACACATAACCAA
GGTGTATTTGATGCATATACTAAAGAAATTAGAAACGCTAGAAGTTCTCATATCATTACT
GGTTTACCAGACGGATATGGTAGAGGACGTATTATTGGAGATTATAGAAGAGTACCTCTT
TATGGTGTAGACGCTTTAATCAAAGATAAATATGCACAACAAGAAGAATTAACATTCCCA
ATGTCTGAGCACAAAATCCGTTTAAGAGAAGAATTATCTGATCAAATTAAATCATTAAAT
GAATTAATTCAATTAGGAGATATGTACGGATTTGACTTAAGAAGACCTGCAAGTGACTCA
AAAGAAGCGATTCAATGGTTATACTTAGCTTATTTAGCAGCTGTTAAAGAACAAAACGGT
GCGGCAATGAGTTTAGGTAGAGTCGATGCATTCTTAGATATCTATATCGAAAGAGACTTA
AAAGCTGCAAAATATAGCGAATTAGAAATTCAAGAATTTATTGACCATTTCGTCATGAAA
TTAAGAATGGTACGTTTTGCTAGAACTCCAGAATATAACCAATTATTTACAGGAGATCCA
ACATGGGTTACTGCTGTATTAGGTGGTATGTCAAATGATGGTAGATCACTTGTTACAAAA
ACAGCATTCAGATTATTACAAACTTTATATAACCTAGGTACATCAGCAGAACCAAACCTG
ACTGTTTTATGGAGCAACAACCTTCCAGAAGGATTTAAAAACTTCACTGCGAAGGTAAGT
ATTGATACTTCAAGTATTCAATATGAAAATGATGATACAATTAGACCACTACATGGCGAT
GACTATGGTATCGCATGTTGCGTGTCACCAATGGCTATTGGTAAAGAAATGCAATTCTTT
GGTGCACGTGCAAACATCGCTAAAGCATTATTATATGCATTAAATGGTGGACGTGACGAA
GTAAGTGGCAAACAAGTATTTGAAAAATCTAAGATGGAAGTTTTAAAAACTGATGTATTA
GATTATGATGTTGTGATGTCACGTTATGAAAAAACATTAGAAGAATTAGCTGAAGTTTAT
GTGAATGCTTTAAACATTATTCACTACATGCATGATAAATATGCATATGAAAAACTAGAA
ATGGCTTTACATGATCGTGATGTTAAGAGATTATTTGCAACTGGTATTGCAGGATTAAGC
GTTGTTGCTGACTCATTATCAGCAATCAAATATGCAAAAGTACACCCAATCTATGATGAA
ACATCAGGATTAATTACTGACTTTGAAACTGTTGGTGAATTCCCATGTTATGGTAATGAT
GATGATAGAGTTGATGATATTGCTGTAGATGTATTACGTAAATTCATGAGCTATATTAGA
AAGAACCCAACATACAGAGAATCACATCCAACAATGAGTGTTTTAACGATTACATCTAAC
GTTGTATACGGTAAAAACACAGGTAATACACCAGATGGTCGTCGTTATGGTGAACCATTT
GCTCCAGGTGCTAACCCAATGCACGGTAGAGATAAATCAGGTGCATTAAAATCATTAATG
TCTGTTGCTAAATTACCATATGAAGATGCAGAAGACGGTATTTCAAATACATTTACAATT
ATTCCAAAAGCATTAGGTCATTCGATAAGTGCTGAAGGTTCTATTGTTCACCTTGTAGAT
GATGTACAAGTAAATAACCTTGTATCCTTATTAGATGGATACTTCACATCTGGTGGATAT
CATTTAAACGTTAACGTGTTTAACAGAGAAACATTAAAAGCAGCTTATGACAACCCAGAA
TTATATCCAAACCTTACAATTAGAGTATCAGGTTATGCTGTAAACTTCTCAAATCTAACG
AATGAACAAAAATTAGAAGTTATGAAGCGTACATTCCATGAAGGATTCTAA

>protein sequence
MAQSWKGFKSGNWEKAVDVADFIKQNYSEYTGDGTFLEGAVESSLSLNESFKDLLKLEKE
KGGVIDLDTKVASTIISHAPGYIDKDIEKIVGLQTDAPLKRGFFPEGGINVAVKSVEAYG
YKVEQETIDIYTNVRKTHNQGVFDAYTKEIRNARSSHIITGLPDGYGRGRIIGDYRRVPL
YGVDALIKDKYAQQEELTFPMSEHKIRLREELSDQIKSLNELIQLGDMYGFDLRRPASDS
KEAIQWLYLAYLAAVKEQNGAAMSLGRVDAFLDIYIERDLKAAKYSELEIQEFIDHFVMK
LRMVRFARTPEYNQLFTGDPTWVTAVLGGMSNDGRSLVTKTAFRLLQTLYNLGTSAEPNL
TVLWSNNLPEGFKNFTAKVSIDTSSIQYENDDTIRPLHGDDYGIACCVSPMAIGKEMQFF
GARANIAKALLYALNGGRDEVSGKQVFEKSKMEVLKTDVLDYDVVMSRYEKTLEELAEVY
VNALNIIHYMHDKYAYEKLEMALHDRDVKRLFATGIAGLSVVADSLSAIKYAKVHPIYDE
TSGLITDFETVGEFPCYGNDDDRVDDIAVDVLRKFMSYIRKNPTYRESHPTMSVLTITSN
VVYGKNTGNTPDGRRYGEPFAPGANPMHGRDKSGALKSLMSVAKLPYEDAEDGISNTFTI
IPKALGHSISAEGSIVHLVDDVQVNNLVSLLDGYFTSGGYHLNVNVFNRETLKAAYDNPE
LYPNLTIRVSGYAVNFSNLTNEQKLEVMKRTFHEGF