ACL_RS00245

Uniprot: A9NEB0
Description: NADH oxidoreductase complex RnfABCDGE type, C subunit
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor: COFACTOR: Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Evidence={ECO:0000256|HAMAP-Rule:MF_00461}; ; Note=Binds 2 [4Fe-4S] clusters per subunit. {ECO:0000256|HAMAP-Rule:MF_00461}
Enzyme regulation:
Function [CC]: FUNCTION: Part of a membrane complex involved in electron transport. {ECO:0000256|HAMAP-Rule:MF_00461}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding: METAL 364 364 Iron-sulfur 1 (4Fe-4S). {ECO:0000256|HAMAP-Rule:MF_00461}.; METAL 367 367 Iron-sulfur 1 (4Fe-4S). {ECO:0000256|HAMAP-Rule:MF_00461}.; METAL 370 370 Iron-sulfur 1 (4Fe-4S). {ECO:0000256|HAMAP-Rule:MF_00461}.; METAL 374 374 Iron-sulfur 2 (4Fe-4S). {ECO:0000256|HAMAP-Rule:MF_00461}.; METAL 403 403 Iron-sulfur 2 (4Fe-4S). {ECO:0000256|HAMAP-Rule:MF_00461}.; METAL 406 406 Iron-sulfur 2 (4Fe-4S). {ECO:0000256|HAMAP-Rule:MF_00461}.; METAL 409 409 Iron-sulfur 2 (4Fe-4S). {ECO:0000256|HAMAP-Rule:MF_00461}.; METAL 413 413 Iron-sulfur 1 (4Fe-4S). {ECO:0000256|HAMAP-Rule:MF_00461}.
Nucleotide binding:
Site:
Gene names (primary): rnfC
Gene names (synonym):
Mass: 48,022
Subunit structure [CC]: SUBUNIT: Composed of six subunits. {ECO:0000256|HAMAP-Rule:MF_00461}.
Gene ontology (GO): plasma membrane [GO:0005886]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron carrier activity [GO:0009055]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]
Gene ontology IDs: GO:0005886; GO:0009055; GO:0046872; GO:0051539; GO:0055114
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. {ECO:0000256|HAMAP-Rule:MF_00461}.; SIMILARITY: Contains 2 4Fe-4S ferredoxin-type domains. {ECO:0000256|HAMAP-Rule:MF_00461}.
Protein families: 4Fe4S bacterial-type ferredoxin family, RnfC subfamily
Coiled coil:
Domain [FT]: DOMAIN 355 384 4Fe-4S ferredoxin-type. {ECO:0000259|PROSITE:PS51379}.; DOMAIN 394 422 4Fe-4S ferredoxin-type. {ECO:0000259|PROSITE:PS51379}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NEB0
MEROPS:
EnsemblBacteria KO: ABX80690
UniPathway: K03615
CDD:
Gene3D:
HAMAP:
InterPro: MF_00461
PANTHER: IPR017896;IPR017900;IPR010208;IPR009051;IPR011538;IPR026902;IPR019554
PIRSF:
PRINTS:
PROSITE:
Pfam: PS00198;PS51379
ProDom: PF01512;PF13237;PF13375;PF10531
SMART:
SUPFAM:
TIGRFAMs: SSF46548

58415-59714(+)

>nucleotide sequence
TTGATCACAAGAACAAGATATATACCTGATGGTAAAGATGTTTTAAAGAAACTACCATTA
ATCCATCACTTAGAAGCACCATATTTATACTATCCAATTACAAACCAAAGATGCCCGGAA
GGTGAAACTTGCGTCGTTTTTGGTCAATTTGTTAAAGTTGGTGAGGTTATTGGTACAAGA
AAGGGTGCTTTCTTTGAGCAACCAATTCACTCAACAGTTAGTGGTGAAGTTGTCGGGCAT
GAAATGAAGTTTGATGCTTCAGGAAAACGTGTAAACTGTATGATTGTTAAAAACGACTTC
AAATATGAATTACATGAGTCTGTTAAAACAAGAACTGATGAAGAAATAGACAAACTTACT
AAAGAAGATTACGTAAATATTACTAAAGAAGCGGGTTTAGTTGGTCTAGGTGGTTCAGGA
TTCCCAACATATATTAAACTAAACACTAAAAATAAAATAGACATTATCTTAGCAAACGGT
GTGGAGTGTGAGCCTAAATTAATTTCAGACTATGAAGTTATGATGGAAAGCCCGGATGAA
CTTATTAGAGGTTTAATCTATGCAATGAAAGCTGTTGGTGCACCAAAAGGTGTAATTGCA
GTTAAGAAAAGATATGTGGAATTAGTAGAAAGAATCCGTTTTTCTCTAAACTCATATACT
GAATATGACATCAAAGTTGTACCAGTTGGTAACCACTATCCACAAGGTTGGGAGTTAGAA
GCAATTGAAGCGGCTACAGGTATTAAGGTACCTCAATTTAAACTTCCAGCGGATTACGGT
ATTATTCCATTTAACGTTTCTACCTTACAATCTATTTATCATGCAGTGAAGTTTAACTTA
CCTGTACTAGAAAGATACTTTGTATTATCAGGTGATGGTGTTGTAAACAAATCATTTAAA
GCTAGAATTGGTACTCCAATTCAAAGTTTAATTCAACTTGCTGGTGGTTATGTAGATAAG
GCAGTGCCTAAAACATTAATCATGGGTGGGCCAATGATGGGTAGTAACGTAACAAATGAT
GATATTGTTACAACACACACAGCAACATCATTAATTGTTCAAAACTCACTTTTATTAAAC
GAAGATCCTTGTATCCACTGTGCAAGCTGTGTATACTCTTGCCCAGTACAAATACAACCG
GTTCAAATTATGAATGCTGTGAAAGCAAACGATAAAGATTTCTTAAAAGCTTTATCAGTT
AATAAATGTATTGAATGTGGATTATGTTCATTTGTATGTCCATCTAAGATTCATTTAACA
GATTACATGCGTGAAGGTAAACGCATCTTAAGAGGTTAA

>protein sequence
LITRTRYIPDGKDVLKKLPLIHHLEAPYLYYPITNQRCPEGETCVVFGQFVKVGEVIGTR
KGAFFEQPIHSTVSGEVVGHEMKFDASGKRVNCMIVKNDFKYELHESVKTRTDEEIDKLT
KEDYVNITKEAGLVGLGGSGFPTYIKLNTKNKIDIILANGVECEPKLISDYEVMMESPDE
LIRGLIYAMKAVGAPKGVIAVKKRYVELVERIRFSLNSYTEYDIKVVPVGNHYPQGWELE
AIEAATGIKVPQFKLPADYGIIPFNVSTLQSIYHAVKFNLPVLERYFVLSGDGVVNKSFK
ARIGTPIQSLIQLAGGYVDKAVPKTLIMGGPMMGSNVTNDDIVTTHTATSLIVQNSLLLN
EDPCIHCASCVYSCPVQIQPVQIMNAVKANDKDFLKALSVNKCIECGLCSFVCPSKIHLT
DYMREGKRILRG