ACL_RS00435

Uniprot: A9NED4
Description: 50S ribosomal protein L4
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. {ECO:0000255|HAMAP-Rule:MF_01328}.; FUNCTION: Forms part of the polypeptide exit tunnel. {ECO:0000255|HAMAP-Rule:MF_01328}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): rplD
Gene names (synonym):
Mass: 22,825
Subunit structure [CC]: SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-Rule:MF_01328}.
Gene ontology (GO): ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]
Gene ontology IDs: GO:0003735; GO:0005840; GO:0006412; GO:0019843
Chain: CHAIN 1 207 50S ribosomal protein L4. /FTId=PRO_1000086505.
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the ribosomal protein L4P family. {ECO:0000255|HAMAP-Rule:MF_01328}.
Protein families: Ribosomal protein L4P family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NED4
MEROPS:
EnsemblBacteria KO: ABX80714
UniPathway: K02926
CDD:
Gene3D:
HAMAP: 3.40.1370.10
InterPro: MF_01328_B
PANTHER: IPR002136;IPR023574;IPR013005
PIRSF: PTHR10746
PRINTS:
PROSITE:
Pfam:
ProDom: PF00573
SMART:
SUPFAM:
TIGRFAMs: SSF52166

84910-85534(+)

>nucleotide sequence
ATGCCAACATTAAATTTATTCAATCAAGCTGGTGAAAAGATTTCTGAAGTTGCTTTAAAT
GACGCAATCTTCGGTATCACACCTAACCAACAAGTGCTATATGATGTTGTCAATGCTCAA
CGCGCAGCGTTAAGACAAGGTACAGCAAAAACGAAGACTCGTGCTGAAGTCCGCGGTGGT
GGTAAAAAACCATGGAGACAAAAAGGTACAGGTCGTGCACGTCAAGGTTCAATCCGCTCA
CCACAATGGAGAGGCGGCGGGATCGTTTTCGGACCAATCCCAAGAAGTTATGCTGTGAAA
GTTAACCAAAAAGTTAAGCAATTAGCTTTAAAGAGTGCACTTTCATATCATGTACTAGCA
GAAAATTTAGTTTTAGTAGACAACATTACAGTTGCTGAGCCTAAAACAAAATTATTCATC
GAAATTATGAACAACTTAAAACTAGACGATAGATCAATCGTGTTAGTTGACAGTGTTGAT
AAAAATTTATTACTAGCATCAAACAACCTACCAGGAGCAGTTGTTAGAGAAGTATCTCAA
GTATCAGTATATGAGTTACTTAAGTTCAAACAAGTGGTCTTGACACAAGGTGCTGTTAAA
TACTACGAGGAGGTATTAGTATAA

>protein sequence
MPTLNLFNQAGEKISEVALNDAIFGITPNQQVLYDVVNAQRAALRQGTAKTKTRAEVRGG
GKKPWRQKGTGRARQGSIRSPQWRGGGIVFGPIPRSYAVKVNQKVKQLALKSALSYHVLA
ENLVLVDNITVAEPKTKLFIEIMNNLKLDDRSIVLVDSVDKNLLLASNNLPGAVVREVSQ
VSVYELLKFKQVVLTQGAVKYYEEVLV