ACL_RS00445

Uniprot: A9NED6
Description: 50S ribosomal protein L2
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. {ECO:0000255|HAMAP-Rule:MF_01320}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): rplB
Gene names (synonym):
Mass: 30,125
Subunit structure [CC]: SUBUNIT: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. {ECO:0000255|HAMAP-Rule:MF_01320}.
Gene ontology (GO): large ribosomal subunit [GO:0015934]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; transferase activity [GO:0016740]; translation [GO:0006412]
Gene ontology IDs: GO:0003735; GO:0006412; GO:0015934; GO:0016740; GO:0019843
Chain: CHAIN 1 276 50S ribosomal protein L2. /FTId=PRO_1000086316.
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the ribosomal protein L2P family. {ECO:0000255|HAMAP-Rule:MF_01320}.
Protein families: Ribosomal protein L2P family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NED6
MEROPS:
EnsemblBacteria KO: ABX80716
UniPathway: K02886
CDD:
Gene3D:
HAMAP: 2.30.30.30;2.40.50.140;4.10.950.10
InterPro: MF_01320_B
PANTHER: IPR012340;IPR022666;IPR014722;IPR002171;IPR005880;IPR022669;IPR022671;IPR014726;IPR008991
PIRSF: PTHR13691
PRINTS: PIRSF002158
PROSITE:
Pfam: PS00467
ProDom: PF00181;PF03947
SMART:
SUPFAM: SM01383;SM01382
TIGRFAMs: SSF50104;SSF50249

85867-86698(+)

>nucleotide sequence
ATGGCAGTTAAAATTTATAAAAGAACGACCAATGGTCGTCGTAATATGAGTGTTCTTACC
TTTGATGAAATTACAACATCTACTCCTGAAAAATCACTTCTTGCGCCAATTACTAAAACT
GGTGGTCGTAACAACCAGGGTAAATTAACCGTTAGACATATCGGTGGTGGAGCAAAGAGA
AAATATCGTATCATTGACTTTAAACGTGATAAAGATAATGTTCCAGGAAAAGTAACATCA
ATTGAGTATGATCCAAATAGAACAGCGAATATCGCATTAATTACTTATTTAGATGGTGAA
AAAAGATATATCATCGCACCTAAAGGCTTACAAGTTGGAGCGTTAATCGTTTCAGGTAGC
GAAATCGATATTAAAGTTGGTAATGCATTACCAGTTATGAGTATCCCAGTAGGTACAATT
GTACACAACATCGAGTTAAAACCTGGTCGTGGTGGACAAATTGCAAGAAGTGCTGGTACA
TCCGCACAAATCTTAGGACGTGAAGAAAAATACGTTTTAGTCCGTCTACAATCTGGTGAA
GTACGTCGTATCTTAGGTACATGTAAAGCAACAATCGGTGAAGTTGGTAACGAATCACAC
GAATTAGTTCGTATCGGTAAAGCTGGTAGAACACGTCACCTAGGTGTACGTCCAACAGTA
CGTGGATCTGTTATGAACCCGAACGATCACCCACACGGTGGTGGTGAAGGTAAACAACCA
ATCGGTAGAAAACAACAAATGACCCCTTGGGGTAAAAAAGCACGTGGTATTAAAACTCGT
GATAAGAAAAAAGCGTCTACAAGCATGATCGTAAGACGTAGAAACGGATAA

>protein sequence
MAVKIYKRTTNGRRNMSVLTFDEITTSTPEKSLLAPITKTGGRNNQGKLTVRHIGGGAKR
KYRIIDFKRDKDNVPGKVTSIEYDPNRTANIALITYLDGEKRYIIAPKGLQVGALIVSGS
EIDIKVGNALPVMSIPVGTIVHNIELKPGRGGQIARSAGTSAQILGREEKYVLVRLQSGE
VRRILGTCKATIGEVGNESHELVRIGKAGRTRHLGVRPTVRGSVMNPNDHPHGGGEGKQP
IGRKQQMTPWGKKARGIKTRDKKKASTSMIVRRRNG