ACL_RS00490

Uniprot: A9NEE5
Description: 50S ribosomal protein L5
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. {ECO:0000255|HAMAP-Rule:MF_01333}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): rplE
Gene names (synonym):
Mass: 20,039
Subunit structure [CC]: SUBUNIT: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome. {ECO:0000255|HAMAP-Rule:MF_01333}.
Gene ontology (GO): ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]
Gene ontology IDs: GO:0000049; GO:0003735; GO:0005840; GO:0006412; GO:0019843
Chain: CHAIN 1 180 50S ribosomal protein L5. /FTId=PRO_1000086578.
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the ribosomal protein L5P family. {ECO:0000255|HAMAP-Rule:MF_01333}.
Protein families: Ribosomal protein L5P family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NEE5
MEROPS:
EnsemblBacteria KO: ABX80725
UniPathway: K02931
CDD:
Gene3D:
HAMAP: 3.30.1440.10
InterPro: MF_01333_B
PANTHER: IPR002132;IPR020930;IPR031309;IPR020929;IPR022803;IPR031310
PIRSF:
PRINTS: PIRSF002161
PROSITE:
Pfam: PS00358
ProDom: PF00281;PF00673
SMART:
SUPFAM:
TIGRFAMs: SSF55282

89915-90458(+)

>nucleotide sequence
ATGAGCGCAGCATTTAAAGAATTATACAACACAAAAATTGTTCCTAAACTAGTTTCTGAC
TTTAATTACGATTCAGTAATGCAAGTACCGAAATTAGAAAAAATTGTTGTTAACATGGGT
GTTGGTGAGGCAGTATCTAATTCTAAATTACTTGATCAAGCAGTTGAAGAGTTAACATTA
CTAACTGGTCAAAAACCTGTTATTACTAAAGCAAAGAAATCAATTTCTAACTTTAAATTA
CGTGAAGGTCAATCCATTGGTGCTAAAGTAACTTTAAGAGGCGATAGAATGTATTACTTC
TTAGAAAAGTTAGTATCAGTTGCATTACCACGTGTTAGAGACTTCCGTGGGGTATCCGCA
AACGCATTTGACGGTCGTGGAAACTACACATTAGGTGTAAAAGAACAAATCATTTTCCCT
GAAATAAACATTGATAAAGTAAATAAAGTTCGTGGGATGGACATTATTATTGTAACAACG
GCACAAACCGATGCAGAAGCTAAAAGCTTATTAACTGAATTTGGTTTCCCGTTCAAGAAG
TGA

>protein sequence
MSAAFKELYNTKIVPKLVSDFNYDSVMQVPKLEKIVVNMGVGEAVSNSKLLDQAVEELTL
LTGQKPVITKAKKSISNFKLREGQSIGAKVTLRGDRMYYFLEKLVSVALPRVRDFRGVSA
NAFDGRGNYTLGVKEQIIFPEINIDKVNKVRGMDIIIVTTAQTDAEAKSLLTEFGFPFKK
W