ACL_RS00645

Uniprot: A9NEH6
Description: rRNA (cytidine-2'-O-)-methyltransferase
EC number: 2.1.1.198
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: S-adenosyl-L-methionine + cytidine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytidine(1402) in 16S rRNA. {ECO:0000256|HAMAP-Rule:MF_01877}.
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. {ECO:0000256|HAMAP-Rule:MF_01877}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): rsmI
Gene names (synonym):
Mass: 31,752
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; rRNA (cytosine-2'-O-)-methyltransferase activity [GO:0070677]; enzyme-directed rRNA 2'-O-methylation [GO:0000453]
Gene ontology IDs: GO:0000453; GO:0005737; GO:0070677
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the methyltransferase superfamily. RsmI family. {ECO:0000256|HAMAP-Rule:MF_01877}.
Protein families: Methyltransferase superfamily, RsmI family
Coiled coil:
Domain [FT]: DOMAIN 13 211 TP_methylase. {ECO:0000259|Pfam:PF00590}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NEH6
MEROPS:
EnsemblBacteria KO: ABX80756
UniPathway: K07056
CDD:
Gene3D: cd11648
HAMAP: 3.30.950.10;3.40.1010.10
InterPro: MF_01877
PANTHER: IPR000878;IPR014777;IPR014776;IPR008189;IPR018063
PIRSF: PTHR21091:SF18
PRINTS: PIRSF005917
PROSITE:
Pfam: PS01296
ProDom: PF00590
SMART:
SUPFAM:
TIGRFAMs: SSF53790

111147-111996(+)

>nucleotide sequence
ATGAACATACAAATAAGTTATGATGTTTTAAAACCAACACTATACATCGTAAGTACACCC
ATTGGTAGCTTAAAGGATATCACCTTAAGAGCAATTGAAGTCTTAAAAAGTGTAGATATC
ATTTTATGTGAAGATACTAGAGTGACTTCAAAACTTCTAGATGCATATGATATTCATGTG
CCACTAAAAAGTTATCAAAAATTTAATGAGCGCTCCATGGTTTTGCAAGTCATTGAATAC
CTAGATAATAAGATGTCAGTCGCACTTGTATCGGATGCAGGTACACCTTTAATTAGTGAC
CCAGGCTTTATTTTAGTCGATGAACTTATTGGTAAAAACTATAATGTTGTAAGTATACCA
GGTGCATCCGCACTGTTATCAGCACTTGTAACATCAGGGATACTTACTCAACCATTTACC
TTTATTGGTTTTTTACCAAGAAAACTTGGTGAAATCAATAAAGTATTAAAAGATTATGTG
TCAAGAAAAGAAAGTTTAATCATTTATGAATCACCAAACCGTGTTCAAAAAACACTATCC
TATATGCTAGATATACTAGGTAATAGAAGAGTAAGTGTAGCAAGAGAGCTTACAAAGAAA
TTTGAAACTTATTATAGAGGCTACATCAAAGATATTTTAGAAACTACACTAGATACACGG
GGCGAATACGTCATTGTTGTAGAAGGAAGTACTACAAGTGATGTCAAAATTGAAGATCCT
GTTGAGCTTGTCTTAAGTTATATGAAACAAGGTTATGATGAAAAAGAAGCCATTAAACAA
GCGAGTAAGGATTTAGGTGTTCATAAATCTGAAGTATATAAAATATTTAAAATAGATAAA
AGTAGTTGA

>protein sequence
MNIQISYDVLKPTLYIVSTPIGSLKDITLRAIEVLKSVDIILCEDTRVTSKLLDAYDIHV
PLKSYQKFNERSMVLQVIEYLDNKMSVALVSDAGTPLISDPGFILVDELIGKNYNVVSIP
GASALLSALVTSGILTQPFTFIGFLPRKLGEINKVLKDYVSRKESLIIYESPNRVQKTLS
YMLDILGNRRVSVARELTKKFETYYRGYIKDILETTLDTRGEYVIVVEGSTTSDVKIEDP
VELVLSYMKQGYDEKEAIKQASKDLGVHKSEVYKIFKIDKSSW