ACL_RS00715

Uniprot: A9NEJ0
Description: Mini-ribonuclease 3
EC number: 3.1.26.-
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor: COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000255|HAMAP-Rule:MF_01468};
Enzyme regulation:
Function [CC]: FUNCTION: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors. {ECO:0000255|HAMAP-Rule:MF_01468}.
Pathway:
Active site: ACT_SITE 11 11 {ECO:0000255|HAMAP-Rule:MF_01468}.
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): mrnC
Gene names (synonym):
Mass: 14,203
Subunit structure [CC]: SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01468}.
Gene ontology (GO): cytoplasm [GO:0005737]; ribonuclease III activity [GO:0004525]; rRNA binding [GO:0019843]; rRNA processing [GO:0006364]
Gene ontology IDs: GO:0004525; GO:0005737; GO:0006364; GO:0019843
Chain: CHAIN 1 125 Mini-ribonuclease 3. /FTId=PRO_0000415979.
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the MrnC RNase family. {ECO:0000255|HAMAP-Rule:MF_01468}.
Protein families: MrnC RNase family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NEJ0
MEROPS:
EnsemblBacteria KO: ABX80770
UniPathway: K11145
CDD:
Gene3D:
HAMAP: 1.10.1520.10
InterPro: MF_01468
PANTHER: IPR008226;IPR000999
PIRSF:
PRINTS: PIRSF005520
PROSITE:
Pfam:
ProDom: PF00636
SMART:
SUPFAM:
TIGRFAMs: SSF69065

129053-129431(+)

>nucleotide sequence
ATGAATGGGTTAGCACTTGCATATTTAGGTGATGCTTATTATGAACTTGAAATCAGAAAA
TATTTGATTACTCAAGGTATTAGAAATGTAGGTAAACTACATACTGAAAAGGTTAGATTA
GCATCGAATGAAGCACAAGCTTCGATTATGAATTATTTTCTTAGTTTAGAGATTTTATCT
GAAGAAGAAATTGATGCCTATAAAAAGGGTAGAAATAAATCTCACAACTCAAGAAAACAA
ATGGATATGGTGACATATCAACAAGCAACCGGATTTGAAAGTTTAATAGGCTATTTATCG
ATAATTGATGAGCAACGCGCTAAAGATTTAATTAATCTAGGTATTACATTTATAAAACAG
GGTGGTTACAATGGCTAA

>protein sequence
MNGLALAYLGDAYYELEIRKYLITQGIRNVGKLHTEKVRLASNEAQASIMNYFLSLEILS
EEEIDAYKKGRNKSHNSRKQMDMVTYQQATGFESLIGYLSIIDEQRAKDLINLGITFIKQ
GGYNG