ACL_RS00985

Uniprot: A9NEP7
Description: peptide chain release factor 1
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. {ECO:0000255|HAMAP-Rule:MF_00093}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): prfA
Gene names (synonym):
Mass: 40,085
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; translation release factor activity, codon specific [GO:0016149]
Gene ontology IDs: GO:0005737; GO:0016149
Chain: CHAIN 1 354 Peptide chain release factor 1. /FTId=PRO_1000117228.
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the prokaryotic/mitochondrial release factor family. {ECO:0000255|HAMAP-Rule:MF_00093}.
Protein families: Prokaryotic/mitochondrial release factor family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NEP7
MEROPS:
EnsemblBacteria KO: ABX80827
UniPathway: K02835
CDD:
Gene3D:
HAMAP: 3.30.160.20
InterPro: MF_00093
PANTHER: IPR014720;IPR005139;IPR000352;IPR004373
PIRSF:
PRINTS:
PROSITE:
Pfam:
ProDom: PF03462;PF00472
SMART:
SUPFAM: SM00937
TIGRFAMs:

192437-193502(+)

>nucleotide sequence
ATGTTTGAAAGATTAGAAGTCATGAGAAAAACGTATTATGCGTTACAAGAAAAATTGGCA
TCAGGTATTAGTGATGTCAAAGAGATTACAAAACTCATGAAAGAACTTAAAAGTTTAGAA
GATGCTGTCGTAGCATATGAAAAATATTTAAGTTTAAAAGAACAATTAAAAGATTTAGAA
GAACTACTTGAGTTAGAAACTGAAAGTAGTGTTTTAGAAATGGCGAAAGCTGAAGAAAAA
TCACTAGAAAGTGATATTGAAAACTTAGAAGAAAGTTTACGTATTTTACTTCTACCTAAA
GATCCAGATGACGATAAAAACGTCATCATTGAAATTAAGGGTGCAGCAGGTGGAGATGAA
GGTAACATCTTTGCAGGTGATTTATTTAAAATGTATTCTAAATATGCTGAAAGTATGGGC
TGGAAAGTTACACTTGTAAATACAACACCAGGTTCTAGTGGTGGTTTTGCAGGTATAGAG
TTCATCATTTCTGGTGAGAATGCATTTAGTTATTTAAAACACGAATCCGGTGTACACCGC
GTACAACGCGTACCTGAAACAGAAAGCCAAGGGCGCATTCATACTTCAACTGCAGTCGTA
CTTGCATTACCTGAACAAGAGGATATTGAGTATGATGTCAAGTGGGAAGATATCCGTTTT
GATACATATAACTCATCAGGTGCAGGTGGACAATCTGTTAATACAACTTATTCAGCAGTT
CGTTTAACGCATATACCTACAAATGTCGTTGTAACATCACAAGAAGAACGTAGTCAACAT
GCAAATAAGGATAGAGCTTATAAATTATTAGTCACTCGTATTTATGATAAAATTCAACAA
GAGCAACTAGAAAAAGAAGGCGAAAGTAGAAAAGCTTTAATCGGACGTGGTAACCGTAGT
GAAAAGATTAGAACCTATAACTACCCACAAAACCGAGTAACAGATCACCGTATTGGTTTA
ACCATTAATAGACTAGATGCAATTATGGAAGGTCGTATTGATTTAATTATCGAACCACTC
ATTAACGAAATCCAAAAAGAAGCATTAGAAGGACAATCAAAGTGA

>protein sequence
MFERLEVMRKTYYALQEKLASGISDVKEITKLMKELKSLEDAVVAYEKYLSLKEQLKDLE
ELLELETESSVLEMAKAEEKSLESDIENLEESLRILLLPKDPDDDKNVIIEIKGAAGGDE
GNIFAGDLFKMYSKYAESMGWKVTLVNTTPGSSGGFAGIEFIISGENAFSYLKHESGVHR
VQRVPETESQGRIHTSTAVVLALPEQEDIEYDVKWEDIRFDTYNSSGAGGQSVNTTYSAV
RLTHIPTNVVVTSQEERSQHANKDRAYKLLVTRIYDKIQQEQLEKEGESRKALIGRGNRS
EKIRTYNYPQNRVTDHRIGLTINRLDAIMEGRIDLIIEPLINEIQKEALEGQSKW