ACL_RS01160

Uniprot: A9NET2
Description: hypothetical protein
EC number: 2.7.7.7
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). {ECO:0000256|SAAS:SAAS00002375}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): dnaE
Gene names (synonym):
Mass: 113,070
Subunit structure [CC]:
Gene ontology (GO): 3'-5' exonuclease activity [GO:0008408]; DNA-directed DNA polymerase activity [GO:0003887]; DNA replication [GO:0006260]
Gene ontology IDs: GO:0003887; GO:0006260; GO:0008408
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the DNA polymerase type-C family. {ECO:0000256|SAAS:SAAS00535146}.
Protein families: DNA polymerase type-C family
Coiled coil:
Domain [FT]: DOMAIN 10 156 PHP. {ECO:0000259|Pfam:PF02811}.; DOMAIN 272 674 DNA_pol3_alpha. {ECO:0000259|Pfam:PF07733}.; DOMAIN 750 833 HHH_6. {ECO:0000259|Pfam:PF14579}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NET2
MEROPS:
EnsemblBacteria KO: ABX80862
UniPathway: K02337
CDD:
Gene3D:
HAMAP:
InterPro:
PANTHER: IPR011708;IPR029460;IPR004013;IPR016195;IPR004805
PIRSF:
PRINTS:
PROSITE:
Pfam:
ProDom: PF07733;PF14579;PF02811
SMART:
SUPFAM:
TIGRFAMs: SSF89550

230239-233179(+)

>nucleotide sequence
TTGATTGGATCGCTATATACGCAAAGTTCATATTCTATCTTAAAATCTACGCTCCATCTG
GAGACTATTTTTAAGCATGCAAAACAGGAAAACCTAGACTTTGTAGCAATTACTGATGAT
AATAATTTACACGGTTTATATAAAGCTTTAGTCTTAAGTAAAAAATATCAAATACCTTTA
ATTTTAGGATTTCAAAAAACATTTAAAGTACTTGGTTATGATTTAGATTTACTCATCTAT
GCACAAAATGATGAAGCATTAAAATCACTGATTGAATTAAACTCATTAACAGCTAGAACA
CCGGATATACCATTTGAATCCTGTGTTCAACTATTAAATAAGTTGATCATTGTTTTACCA
AGTACTCAAAGTTTTATCTACCAACATTATGAGATGAGTGAGCGTATTTATGAAGTTATT
TCTTCATTACATAAATCACTAAAAAACTTCTATTTAGGACTGGGTAATGCAACAGATTTT
GAAGTTGATAAGATAACACCTATTTTGAAGAAAATCGCCTTAAATGAAGATTTAAAGTAT
TTACCTACATATCAACAAAGTTATGAGGATGAAGAAAATAAAACAACTTATGACATTGTA
AATACAATTAAAGATAGTCAGTTTAAATCATTAAATGTTTCCATGCATTTATTGAGTAAA
AATGAATTAGTTAAAAAATATGAACAAGAAAAGAATATATTTAAAAACGTAGACGCTGTC
TTTGGTCGTGTAAACTATACGTATTTAGATAATACCCAAAGCCTACCTGTTTTTCCAACA
AAGGATAATGTTGAAAGCCATATTTATTTATATGCACTTGCACATAAAGGACTAGAAAAA
AGGTTGGAAAATAGTGGTGTTAGAAAATCAACCGACTATATTCAAAGATTAAATGAAGAA
TTAGAAGTTATACACCAAATGGGTTATGACGATTACTTTTTAATTGTCTATGATTTTGTA
AGGTTTGCTAAAACAAACGATATATTAGTTGGTCCCGGTCGTGGTAGTGCGGCAGGTAGT
TTGGTTGCCTACTGCTTAGGTATTACAGAAGTAGATCCCATACAATATGATTTATTATTT
GAACGTTTCTTAAACATCGATAGAAAATCCATGCCGGATATCGATTTAGATTTTCCAGAT
GTTAAAAGAGATTTAGTGATTGACTATGTTAAAGAAAAATATGGACTTAATCATGTTGTA
ACGATGACTACATTTACAAACTTAACAACCAAAACATCCATGCGTGATATTGCAAGACAA
ATGAATTTAAGTCAAGAACGTATTAATGCAATTATTGCAAGTCACACCAAGGGTATCTTA
GATGAAAGTGATAGAGAAGCACAAAAATTAGTTAAAGTAGCTTCTACAATTGAAGGTATA
CCTCGTCAAACAGGGACCCATCCAGCAGGTATCATCTTATCTAAACAAGACTTAACTACT
TTAGTACCGTTAATGAATGGTCCTAAAGATATATATCAATCTCAATTGGAGGCGAGTGAT
CTAGAGTCACTTGGATTCTTAAAAATTGATTTTCTAGGCTTAAAGAATCTAACCATGATT
GAAGATATATTAAAGTTAGAACAAAACAAATTAAAATTATCTGACATGCCTTTAGATGAT
AAAAAGACATTTGAATTACTATCCAATGCCGATGTAGAAGGTGTCTTTCAACTAGAATCT
CAAGGTATGAGAAATGTGATTAGAAAGTTAAGACCGTCTCACTTTGAAGATATTGTTGCA
TTACTTGCATTATTTAGGCCGGGGCCGATGCAGTTTATCGATGATTATATAAAGAGGCGA
CATGGTGATACATATGAAAAGTTAGATAGTGATATTGATGAAATCTTAAAACCTACGTAT
GGGATTATTGTCTATCAAGAACAGATCATGAAAATCTTTCAAGTGTATGCGGGCTATAAA
CTAAGTGAAGCAGATATTATAAGACGTGCGATTTCTAAGAAGAATAGAGATATGATTGAT
AGAGAAAAGGCGCGGTTTATAGAAAAATCCGTACGACTAAATCGTGATGCCGAAACTGCT
GAAAAAATCTATAATCACATAGAAAAATTTGCTGATTACGGATTTAACAGAAGTCATAGT
GTGGCATACGCATTTATCGCTTATTACATGGCATATTTAAAAACACACTATTATGCATCC
TTTATATCCGTGCTTATGAGTCAAAACACTTCAAACACTGCCTACTTAAAAGAGTTAGTG
CTTGATGCTCAAAATAAAGGTTTAGTTGTTTATCCACCAAACATTAATTTATCAAAATTA
GACTTTATACCTTATAAATCAGGTATCTTAGCTCCGCTTACGATGATTAAAGGCATTGGT
TTAACAACAGCTAAAAAAATAGTTGAACTTCAACCATTTGATTCGTATGATCATTTTAAA
GAAAAAGTGTTTAAGGTATTAAATGAAAAATCTATTGAAATCTTAATTCATGCAAATGCA
TTAGATGTCTTTGGTCTGAATCATAAAGAACTCTTAGATCAAAATAATTTAAATCAAACA
GGATTTGAACAGTTTTTAGATGATTATAAGAAAACAAGGTTAGAAGAATTGCCGTTTAAT
ACACTGAAGGAAAAAGAGATTGAAGTCTTAGGGTTTAATTTGAAATATTTAAAGGATGAA
GTACTCATACGTTTAAATGAAACACACAAATTAAAGCCATTATCACTAAAAGAACAGTCA
ATTCGCACCATTGGTATGATAGAAAGTGTTAAAATAATAACAACTAAAAAAGGTGATGAA
ATGGCATTTATTACCTTTAGTAATGGTATAAGTTTAGATTTAACCGTATTTCCAAATCAA
TATAAGTCATATAAAGAACTACTAAGTGATACCTATGTTTATATTGAAGCAACAAAGGAT
CAAACCCAAGCAGTAGAAAATAAATATATTATAAATAAAATAAAGAAAGTTAAGGTGTAG

>protein sequence
LIGSLYTQSSYSILKSTLHLETIFKHAKQENLDFVAITDDNNLHGLYKALVLSKKYQIPL
ILGFQKTFKVLGYDLDLLIYAQNDEALKSLIELNSLTARTPDIPFESCVQLLNKLIIVLP
STQSFIYQHYEMSERIYEVISSLHKSLKNFYLGLGNATDFEVDKITPILKKIALNEDLKY
LPTYQQSYEDEENKTTYDIVNTIKDSQFKSLNVSMHLLSKNELVKKYEQEKNIFKNVDAV
FGRVNYTYLDNTQSLPVFPTKDNVESHIYLYALAHKGLEKRLENSGVRKSTDYIQRLNEE
LEVIHQMGYDDYFLIVYDFVRFAKTNDILVGPGRGSAAGSLVAYCLGITEVDPIQYDLLF
ERFLNIDRKSMPDIDLDFPDVKRDLVIDYVKEKYGLNHVVTMTTFTNLTTKTSMRDIARQ
MNLSQERINAIIASHTKGILDESDREAQKLVKVASTIEGIPRQTGTHPAGIILSKQDLTT
LVPLMNGPKDIYQSQLEASDLESLGFLKIDFLGLKNLTMIEDILKLEQNKLKLSDMPLDD
KKTFELLSNADVEGVFQLESQGMRNVIRKLRPSHFEDIVALLALFRPGPMQFIDDYIKRR
HGDTYEKLDSDIDEILKPTYGIIVYQEQIMKIFQVYAGYKLSEADIIRRAISKKNRDMID
REKARFIEKSVRLNRDAETAEKIYNHIEKFADYGFNRSHSVAYAFIAYYMAYLKTHYYAS
FISVLMSQNTSNTAYLKELVLDAQNKGLVVYPPNINLSKLDFIPYKSGILAPLTMIKGIG
LTTAKKIVELQPFDSYDHFKEKVFKVLNEKSIEILIHANALDVFGLNHKELLDQNNLNQT
GFEQFLDDYKKTRLEELPFNTLKEKEIEVLGFNLKYLKDEVLIRLNETHKLKPLSLKEQS
IRTIGMIESVKIITTKKGDEMAFITFSNGISLDLTVFPNQYKSYKELLSDTYVYIEATKD
QTQAVENKYIINKIKKVKV