ACL_RS01245

Uniprot: A9NEU9
Description: ribulose-phosphate 3-epimerase
EC number: 5.1.3.1
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: D-ribulose 5-phosphate = D-xylulose 5-phosphate. {ECO:0000256|PIRNR:PIRNR001461}.
Cofactor: COFACTOR: Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; Evidence={ECO:0000256|PIRSR:PIRSR001461-2}; ; Note=Binds 1 divalent metal cation per subunit. {ECO:0000256|PIRSR:PIRSR001461-2}
Enzyme regulation:
Function [CC]:
Pathway:
Active site: ACT_SITE 32 32 Proton acceptor. {ECO:0000256|PIRSR:PIRSR001461-1}.; ACT_SITE 171 171 Proton donor. {ECO:0000256|PIRSR:PIRSR001461-1}.
Binding site: BINDING 6 6 Substrate. {ECO:0000256|PIRSR:PIRSR001461-3}.; BINDING 63 63 Substrate. {ECO:0000256|PIRSR:PIRSR001461-3}.; BINDING 173 173 Substrate; via amide nitrogen. {ECO:0000256|PIRSR:PIRSR001461-3}.
Calcium binding:
DNA binding:
Metal binding: METAL 30 30 Divalent metal cation. {ECO:0000256|PIRSR:PIRSR001461-2}.; METAL 32 32 Divalent metal cation. {ECO:0000256|PIRSR:PIRSR001461-2}.; METAL 63 63 Divalent metal cation. {ECO:0000256|PIRSR:PIRSR001461-2}.; METAL 171 171 Divalent metal cation. {ECO:0000256|PIRSR:PIRSR001461-2}.
Nucleotide binding:
Site:
Gene names (primary): rpe
Gene names (synonym):
Mass: 23,663
Subunit structure [CC]:
Gene ontology (GO): metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]
Gene ontology IDs: GO:0004750; GO:0005975; GO:0006098; GO:0046872
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the ribulose-phosphate 3-epimerase family. {ECO:0000256|PIRNR:PIRNR001461}.
Protein families: Ribulose-phosphate 3-epimerase family
Coiled coil:
Domain [FT]:
Motif:
Region: REGION 138 141 Substrate binding. {ECO:0000256|PIRSR:PIRSR001461-3}.; REGION 193 194 Substrate binding. {ECO:0000256|PIRSR:PIRSR001461-3}.
EMBL: CP000896
ProteinModelPortal: A9NEU9
MEROPS:
EnsemblBacteria KO: ABX80879
UniPathway: K01783
CDD:
Gene3D: cd00429
HAMAP: 3.20.20.70
InterPro:
PANTHER: IPR013785;IPR026019;IPR000056;IPR011060
PIRSF: PTHR11749
PRINTS: PIRSF001461
PROSITE:
Pfam: PS01085
ProDom: PF00834
SMART:
SUPFAM:
TIGRFAMs: SSF51366

253468-254101(+)

>nucleotide sequence
ATGAAAGTTGCACCGTCGATATTGACAGCAAATTTTATACGCTTGGAAGACGAGCTTAAA
TCCATCGAGGAAGGTTCGGATTATATTCATGTGGACGTTATGGATGGCCACTTTGTACCA
AACATTAGTTTTGGACCAGCGATAGTTTCGCAAATTGGTGAACTCACTAAACTACCAATG
GATATTCATCTTATGGTAGAGCACCCATTAGATTGGATTGATAAAGTAATCTTTCCAACT
ACAGAATTTATTACAATCCATGCGGAATGTAACAGATTTAAAGAAAGTATTCGCAGAATT
CTTTATTTAGGTAAAAAAGCTGGTTTAGCAATTAAACCAAGCACAGATGTAGATTTTATT
AAACCATACTTAAGTCAACTAGACCTTGTATTAGTCATGGGTGTTGAACCTGGATATGGT
GGACAATTATTCATCCAAAATCAATTGAAAAAAATCGAAGAACTTGCACAACTTAAAGAA
GAAAACGGATATCACTACGAAATTCAAGTAGATGGTGGTATTAACGTTTCTACAGCAAAA
CAAGTCAAAGATGCAGGAGCAACCATAGTTGTTGCAGGTACATTTATCTTTAATTACGAA
GATCGTAAAGAAAGAATCGAATCACTTAAATAG

>protein sequence
MKVAPSILTANFIRLEDELKSIEEGSDYIHVDVMDGHFVPNISFGPAIVSQIGELTKLPM
DIHLMVEHPLDWIDKVIFPTTEFITIHAECNRFKESIRRILYLGKKAGLAIKPSTDVDFI
KPYLSQLDLVLVMGVEPGYGGQLFIQNQLKKIEELAQLKEENGYHYEIQVDGGINVSTAK
QVKDAGATIVVAGTFIFNYEDRKERIESLK