ACL_RS01525

Uniprot: A9NEZ7
Description: DNA-directed RNA polymerase subunit omega
EC number: 2.7.7.6
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). {ECO:0000256|HAMAP-Rule:MF_00366, ECO:0000256|SAAS:SAAS00094481}.
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. {ECO:0000256|HAMAP-Rule:MF_00366, ECO:0000256|SAAS:SAAS00366146}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): rpoZ
Gene names (synonym):
Mass: 7,960
Subunit structure [CC]: SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. {ECO:0000256|HAMAP-Rule:MF_00366, ECO:0000256|SAAS:SAAS00366140}.
Gene ontology (GO): DNA binding [GO:0003677]; DNA-directed RNA polymerase activity [GO:0003899]; transcription, DNA-templated [GO:0006351]
Gene ontology IDs: GO:0003677; GO:0003899; GO:0006351
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the RNA polymerase subunit omega family. {ECO:0000256|HAMAP-Rule:MF_00366, ECO:0000256|SAAS:SAAS00573536}.
Protein families: RNA polymerase subunit omega family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: ABX80927
UniPathway: K03060
CDD:
Gene3D:
HAMAP: 3.90.940.10
InterPro: MF_00366
PANTHER: IPR003716;IPR006110;IPR012293
PIRSF:
PRINTS:
PROSITE:
Pfam:
ProDom: PF01192
SMART:
SUPFAM: SM01409
TIGRFAMs: SSF63562

314610-314826(+)

>nucleotide sequence
ATGAAAAAAAGAAAACATGGTTTAAACTACCCAACAATTGACGTACTATTAGAAAAGATT
GATTCTAAGTATAAATTAGTATATGCAGCGAGTAAAGTTGCTCATATCATTGAAAGAGAA
AATTTGGATGTTAAAGATTCCAAATCAGTCACAAGTGTAGGCAAAGCGTTAGAAGAAATT
GCAAATGGTAAAGTAACTGTTACGTTCATTGACTAA

>protein sequence
MKKRKHGLNYPTIDVLLEKIDSKYKLVYAASKVAHIIERENLDVKDSKSVTSVGKALEEI
ANGKVTVTFID