ACL_RS01585

Uniprot: A9NF09
Description: transcription termination factor NusA
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Participates in both transcription termination and antitermination. {ECO:0000256|HAMAP-Rule:MF_00945}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): nusA
Gene names (synonym):
Mass: 40,375
Subunit structure [CC]: SUBUNIT: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA. {ECO:0000256|HAMAP-Rule:MF_00945}.
Gene ontology (GO): cytoplasm [GO:0005737]; RNA binding [GO:0003723]; transcription factor activity, sequence-specific DNA binding [GO:0003700]; DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]
Gene ontology IDs: GO:0003700; GO:0003723; GO:0005737; GO:0006353; GO:0031564
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the NusA family. {ECO:0000256|HAMAP-Rule:MF_00945}.; SIMILARITY: Contains 1 KH domain. {ECO:0000256|HAMAP-Rule:MF_00945}.; SIMILARITY: Contains 1 S1 motif domain. {ECO:0000256|HAMAP-Rule:MF_00945}.
Protein families: NusA family
Coiled coil:
Domain [FT]: DOMAIN 309 358 KH. {ECO:0000259|PROSITE:PS50084}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NF09
MEROPS:
EnsemblBacteria KO: ABX80939
UniPathway: K02600
CDD:
Gene3D:
HAMAP: 2.40.50.140;3.30.1480.10;3.30.300.20
InterPro: MF_00945_B
PANTHER: IPR015946;IPR025249;IPR004088;IPR009019;IPR012340;IPR030842;IPR022967;IPR013735;IPR010213
PIRSF:
PRINTS:
PROSITE:
Pfam: PS50084
ProDom: PF13184;PF08529
SMART:
SUPFAM: SM00316
TIGRFAMs: SSF50249;SSF54814;SSF69705

326573-327650(+)

>nucleotide sequence
ATGATCAGTAAAGCATTTTTCCAAAATATTGAAGAAGTCGCTGAAGATAACGACTTAAAT
AAAGAACAAGTATTCCATGCTTTTGAGCAAGGATTAATTGCTGCATGTAAAAAGCAATTA
GGTGTACAAACATGCCGTGTAGAATTTAAAGAAGAAAAACATGAATTATTAATCTATGGT
CAATATTATGTATTACCTGAAGGTGAACTTAATTTAGAACTAGATAAAAAGTATACTTTC
TTAAAATTAGAAGATGCTAAAGCATTAAAGAAATCAGCTAAAGCTGGCGAGATTTTAGAA
GTAAAAATTGAACCAAGTGAATTTAGCTATAATGCAAGCCGTGATTTAAAACATAGATTC
AATGAAGTTTTAAATCAAATTAAGAAAGAAAACATCTATCAAGGATTAAAAGATCTTCAA
TATGAAATGGTAACAGCTAGAGTCTTAGAAGAAGAAAAAGACTTCTACCGTATTGAAATC
AACAAGGATGTTATTACAATGCTACCTAAAAAGGAAGCATTACCTACAGATAAATTCCAT
GTAGGGGATCGTATTAAAGTTTATGTTACGGATGTAGAAATGAAGACGAAAGGTCCTAAA
ATTTATGTTTCTCGTACACATGTTGCTTTAGTCACTCGTCTACTTGAAGAATATGTACCA
GAAATCAAAGATGGTACGATTGAAGTTTTAGGTATCGCACGTGATCCAGGTGATCGTTCT
AAAGTAGGTTTAAAATCTAATAATGAGAACGTTGACGTTATCGGAGCTACAGTTGGTGAA
GGTGGCGTACGTATTAAAGAAATCTCTAAATTCCTATCTGGAGAAAAAATTGATTTATTC
AGATGGAGTGATAATGAACAAGAACTCATTGGTAACTCTTTACAACCGGCACCGGTTGTA
GCAGTTACGAGAGTAAATCCTAAAGAAAAGAGTGCATTAGCAATTGTGCCTGATGCTCAA
TTATCTTTAGCAATTGGTAAACTTGGTCAAAATGTTAAGTTAGCAGTTCAAGCAAGTGGT
TGGTCTATTGATATTAAATCTGAGACTACAGCAGCTGAAGAAGGCATTATTTACTAA

>protein sequence
MISKAFFQNIEEVAEDNDLNKEQVFHAFEQGLIAACKKQLGVQTCRVEFKEEKHELLIYG
QYYVLPEGELNLELDKKYTFLKLEDAKALKKSAKAGEILEVKIEPSEFSYNASRDLKHRF
NEVLNQIKKENIYQGLKDLQYEMVTARVLEEEKDFYRIEINKDVITMLPKKEALPTDKFH
VGDRIKVYVTDVEMKTKGPKIYVSRTHVALVTRLLEEYVPEIKDGTIEVLGIARDPGDRS
KVGLKSNNENVDVIGATVGEGGVRIKEISKFLSGEKIDLFRWSDNEQELIGNSLQPAPVV
AVTRVNPKEKSALAIVPDAQLSLAIGKLGQNVKLAVQASGWSIDIKSETTAAEEGIIY