ACL_RS01655

Uniprot: A9NF23
Description: peptide chain release factor 2
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. {ECO:0000255|HAMAP-Rule:MF_00094}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): prfB
Gene names (synonym):
Mass: 41,587
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; translation release factor activity, codon specific [GO:0016149]
Gene ontology IDs: GO:0005737; GO:0016149
Chain: CHAIN 1 365 Peptide chain release factor 2. /FTId=PRO_1000075522.
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the prokaryotic/mitochondrial release factor family. {ECO:0000255|HAMAP-Rule:MF_00094}.
Protein families: Prokaryotic/mitochondrial release factor family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NF23
MEROPS:
EnsemblBacteria KO: ABX80953
UniPathway: K02836
CDD:
Gene3D:
HAMAP: 3.30.160.20
InterPro: MF_00094
PANTHER: IPR014720;IPR005139;IPR000352;IPR020853;IPR004374
PIRSF: PTHR11075:SF6
PRINTS:
PROSITE:
Pfam:
ProDom: PF03462;PF00472
SMART:
SUPFAM: SM00937
TIGRFAMs:

343069-344167(+)

>nucleotide sequence
ATGGAAAAGTACGAAGTAAATAAGACACTAGAACTTTTTGAAACAAAAATTAAAGATTTA
GAAAATGCTTTAGATTTAGATGCTATTAATAACAGATTAAAAGAAATCGAACCCATCATG
GCAAATCCTAATTTTTGGAATGATTCAAATCAAGCAAAAAAGATTAGCCAAGAATTAAAT
CAACTTACAGAGAAAAAACAAACTATTACATCGATTCAAAACCAATATGAGGATGCCTTA
ATGTGGCTTGAAGAAGCCAAAGAAGGTACTGAGAGTTGGGATATTTTAGAAGCTGAAATT
GATTCACTTCAAAAAAAGATATCTGAGTTTGAAATTGAAGTATTACTCAATGGAGAATAT
GATCATAACAATGCAATCTTAGAACTTCATCCAGGTGCTGGTGGTACAGAGTCCATGGAC
TGGTGTGGTATTTTAATGCGTATGTATGAACGCTTTGCTGGCTATAAAGGTTATAAGGTA
GAAATACTAAACTACTTAGCGGGTGAAGAAGCAGGTGTTAAATCTGTTACATTACGTATT
TCTGGTCCATATGCTTATGGTAATTTAAAGTCTGAACGTGGTGTTCACAGATTAGTTCGT
ATCTCACCATTTGACTCCAATAAAAGAAGACATACTTCCTTTGTTTCATGTGATGTAGCA
CCTGAAATTGATGAAACAAGTGAAGTTGAATTAAAAGATGATGATATTCGTATGGATACA
TTCCAATCCTCTGGTGCAGGTGGTCAGTCGGTTAACACAACTTACTCTGCTGTAAGATTA
ACACATATACCAACTGGTATTGTTGTTAATATTCAAAATGAACGTAGTCAGATTAAGAAT
AAAGAAGCAGCAATGCAAATTTTAAAATCTAAACTGATACAAAAAGAACTAGAAGAAAAA
CAAGCGAAGTTAAATGCCCTTAAGGGTGAAAAATCAGATATTGGTTGGGGTAGTCAAATT
AGATCTTATGTATTCCAACCTTATCAAATGGTCAAAGACCACAGAACTAATTATGAAGTT
GGTAATATTCAGTCTGTCATGGATGGAGATATTGACGGTTTCATTAATGCTTATTTAAAG
AGTAAAGCCTATGAATAA

>protein sequence
MEKYEVNKTLELFETKIKDLENALDLDAINNRLKEIEPIMANPNFWNDSNQAKKISQELN
QLTEKKQTITSIQNQYEDALMWLEEAKEGTESWDILEAEIDSLQKKISEFEIEVLLNGEY
DHNNAILELHPGAGGTESMDWCGILMRMYERFAGYKGYKVEILNYLAGEEAGVKSVTLRI
SGPYAYGNLKSERGVHRLVRISPFDSNKRRHTSFVSCDVAPEIDETSEVELKDDDIRMDT
FQSSGAGGQSVNTTYSAVRLTHIPTGIVVNIQNERSQIKNKEAAMQILKSKLIQKELEEK
QAKLNALKGEKSDIGWGSQIRSYVFQPYQMVKDHRTNYEVGNIQSVMDGDIDGFINAYLK
SKAYE