ACL_RS01735

Uniprot: A9NF39
Description: signal recognition particle-docking protein FtsY
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). {ECO:0000256|HAMAP-Rule:MF_00920}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding: NP_BIND 121 128 GTP. {ECO:0000256|HAMAP-Rule:MF_00920}.; NP_BIND 203 207 GTP. {ECO:0000256|HAMAP-Rule:MF_00920}.; NP_BIND 267 270 GTP. {ECO:0000256|HAMAP-Rule:MF_00920}.
Site:
Gene names (primary): ftsY
Gene names (synonym):
Mass: 35,758
Subunit structure [CC]: SUBUNIT: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. {ECO:0000256|HAMAP-Rule:MF_00920}.
Gene ontology (GO): cytoplasm [GO:0005737]; intrinsic component of plasma membrane [GO:0031226]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]
Gene ontology IDs: GO:0003924; GO:0005525; GO:0005737; GO:0006614; GO:0031226
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the GTP-binding SRP family. FtsY subfamily. {ECO:0000256|HAMAP-Rule:MF_00920}.
Protein families: GTP-binding SRP family, FtsY subfamily
Coiled coil:
Domain [FT]: DOMAIN 288 301 SRP54. {ECO:0000259|PROSITE:PS00300}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NF39
MEROPS:
EnsemblBacteria KO: ABX80969
UniPathway: K03110
CDD:
Gene3D:
HAMAP: 3.40.50.300
InterPro: MF_00920
PANTHER: IPR003593;IPR027417;IPR013822;IPR004390;IPR000897
PIRSF:
PRINTS:
PROSITE:
Pfam: PS00300
ProDom: PF00448;PF02881
SMART:
SUPFAM: SM00382;SM00962;SM00963
TIGRFAMs: SSF47364;SSF52540

362960-363917(+)

>nucleotide sequence
ATGGGTTTTTTCTCACGTCTGTTTAAAAAGAAACCAAAAAATGATAAATATCAAATGGGT
CTACATAAAAGTAGAAGTTCATTTGATAACTTAAAGAAATTATTAGATGAGTCTGATACG
ATTAATGATGATTTATTTGATGCTATAGAAGATTTACTTATCTCTGCCGATATTGGTGTA
GATACTGTTTTACATTTTACAAATGAACTTCGAAATGAAGTTATAAATAAACAATTTGAA
AATCCAAGTGACTTAAGTGAAACGATTGTTGATAAATTATTTGAAATATATTTAAAAGAT
GAATTTGTAGATACAACATTAAGTTTTACAGAAGGCGAAGTCAATGTCTTTTTATTTGTA
GGAGTTAATGGTGTTGGTAAAACAACTACTATTGGTAAACTTGCAAAACAATATAAAGAC
CAAGGTAAAAAAGTCTTAATGGTTGCAGGTGATACCTTTAGAGCTGGTGCAATTGAACAA
CTTTATGAGTGGAGTAAGCGTGCCAAGGTAGATTTTTACCAAAAAGATGCTGGATCTGAC
CCTTCAAGTGTCATATTTGAAGCACTAGAAAAAGCTAAAAAAGAAACATATGACCTTGTA
TTAGTCGATACTGCTGGTAGACTTCAAAATAAAGTGAACTTAATGAATGAGTTATCAAAA
ATGAAACGTGTCATTGAAAAAGCTCTACCAAGTCAACCTGCTGAAACATTACTGGTTATT
GATGCAACTACTGGTCAAAATGGTATGAATCAAGCAAAAGTGTTTAATGAAGCAACAGAT
CTAACTGGGATTGTTTTAACCAAGTTAGATGGTACTGCAAAAGGTGGTATTGTACTTGCG
ATTAGACACTTATATAACCTACCAATTAAATATGTAGGCCTTGGTGAAAAAATTGATGAT
TTAGTACCATTTGATATAGAAGATTATATTTATAACCTATTTAAAGGATTCTTCTAA

>protein sequence
MGFFSRLFKKKPKNDKYQMGLHKSRSSFDNLKKLLDESDTINDDLFDAIEDLLISADIGV
DTVLHFTNELRNEVINKQFENPSDLSETIVDKLFEIYLKDEFVDTTLSFTEGEVNVFLFV
GVNGVGKTTTIGKLAKQYKDQGKKVLMVAGDTFRAGAIEQLYEWSKRAKVDFYQKDAGSD
PSSVIFEALEKAKKETYDLVLVDTAGRLQNKVNLMNELSKMKRVIEKALPSQPAETLLVI
DATTGQNGMNQAKVFNEATDLTGIVLTKLDGTAKGGIVLAIRHLYNLPIKYVGLGEKIDD
LVPFDIEDYIYNLFKGFF