ACL_RS02015

Uniprot: A9NF94
Description: methylglyoxal synthase
EC number: 4.2.3.3
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: Glycerone phosphate = methylglyoxal + phosphate. {ECO:0000255|HAMAP-Rule:MF_00549}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site: ACT_SITE 60 60 {ECO:0000255|HAMAP-Rule:MF_00549}.
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): mgsA
Gene names (synonym):
Mass: 13,604
Subunit structure [CC]:
Gene ontology (GO): methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]
Gene ontology IDs: GO:0008929; GO:0019242
Chain: CHAIN 1 122 Methylglyoxal synthase. /FTId=PRO_1000081949.
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the methylglyoxal synthase family. {ECO:0000255|HAMAP-Rule:MF_00549}.
Protein families: Methylglyoxal synthase family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NF94
MEROPS:
EnsemblBacteria KO: ABX81024
UniPathway: K01734
CDD:
Gene3D:
HAMAP: 3.40.50.1380
InterPro: MF_00549
PANTHER: IPR004363;IPR018148;IPR011607
PIRSF:
PRINTS: PIRSF006614
PROSITE:
Pfam: PS01335
ProDom: PF02142
SMART:
SUPFAM: SM00851
TIGRFAMs: SSF52335

423884-424253(+)

>nucleotide sequence
ATGAGAATAGCACTTATCGCACACGATAAAAAGAAAGATTTAATGATTCAATTTACTAAA
GATCATGAAGACTATTTATCAAACCATACATTATACGCAACCGGGACAACTGGTACACGT
ATTATGGAACACACAAAACTTAAAGTTAATTTAAAGAAATCAGGTCCACTCGGTGGTGAC
CAAGAAATTGGTTCAATGATCGCTAATGGTAAACTCGATTTAGTATTTTTCTTTAGAGAC
CCATTAACTGCTCAACCACATGAACCTGATGTATCTGCACTATTAAGACTTTGTGATGTT
TATGATGTTCCACTAGCAACAAACAATGCTGCTGCGGACTTGTTTATCAAACACTTAAAA
GGGAAGTAA

>protein sequence
MRIALIAHDKKKDLMIQFTKDHEDYLSNHTLYATGTTGTRIMEHTKLKVNLKKSGPLGGD
QEIGSMIANGKLDLVFFFRDPLTAQPHEPDVSALLRLCDVYDVPLATNNAAADLFIKHLK
GK