ACL_RS02205

Uniprot: A9NFD0
Description: 23S rRNA (uracil-5-)-methyltransferase RumA
EC number: 2.1.1.35
Annotation score: 1 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): trmA
Gene names (synonym):
Mass: 49,346
Subunit structure [CC]:
Gene ontology (GO): 4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity [GO:0030697]
Gene ontology IDs: GO:0003723; GO:0030697; GO:0046872; GO:0051539
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. {ECO:0000256|SAAS:SAAS00561307}.
Protein families: Class I-like SAM-binding methyltransferase superfamily, RNA M5U methyltransferase family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NFD0
MEROPS:
EnsemblBacteria KO: ABX81060
UniPathway:
CDD:
Gene3D:
HAMAP: 2.40.50.140;3.40.50.150
InterPro:
PANTHER: IPR001566;IPR030390;IPR012340;IPR029063;IPR010280
PIRSF:
PRINTS:
PROSITE:
Pfam: PS51687;PS01230
ProDom: PF05958
SMART:
SUPFAM:
TIGRFAMs: SSF50249;SSF53335

461882-463136(+)

>nucleotide sequence
ATGAGATTAAAAGTAAAAACAAATGATCTTGATTACCAAGGTCAAGGTGTAACAAGAATA
GATGATAAAGTAACCTTTATAAAAGGTATGTTTGATGATGAAGTAGGCATCATAGAAATC
ACAAAATCAAAAAAGAATTTCCAACAAGCAAAACTTGTAGAACTTATTCAAAAAAATAAA
CAACGTGTATCTGAAAACTCTTTTGACTATGCACCGTTTTTTGGTCTATCCTTAAAAGCA
GAATGCCTATGGCAACAAAAGATTACTAAAGAAACGATTAAAAAAATAACCAATTTAGAT
GTTGAAGTAGAAGATACTATCACAGATGGTAAGAAACTAAACTACAGAAATAAAATCACT
TTACATGTGAAACATATTGGTGGTTCATTAAAGATTGGTACCTATGAAGAAAACTCTAAT
TATCTTGAACCGATTGAAACACATCATCTTGCACTACCTGTCATAAATGATAAAATTACA
GTTTTAAATAAATGGCTCAAAACCTTTAAATTAGAAACGAATGATATTAAAAACTTTACC
CTTAGAACAAACGGTAAAGATGTGATGCTTATCATTGGTATAAAACTTAAGTTTGAAGGT
ACAGAAAGCATCATAGATGAACTTAAAAAGCACTTTGAATCCATCTACCTAAATATTGAA
AAAAGAAGTTTTGAAAACCTATCAGATGAATCGATTCATGTTTATGGTCTAGAGACCTTA
AAGATGACATTTAATCACTTATCATTTGAAATAGGACCTGAAAGTTTCTTCCAGGTAAAT
AAAGATGTAGCAATTTTAATGTATGATGAAATTAAGAAACTTACCCAAAATCACACAGTC
ATTGATGCCTATGCTGGTATGGCAAGTATTGGTCAATATATTGATGCTAAAAAGGTATAC
GCAATTGAATCTAATCTAGATTCAATTATTCAAGCTAAGAAGATATTAAAGGTAAATCAA
GTAGACCATGTAGAGTTGATTCATGGACAAGTAGAAGAAAAACTAGAAGCATACATTAAA
CATGCAGATGCTATAGTGTTTGATCCACCAAGAAGTGGATTAACGGAAAGTATTATTGAA
CTAGTAAAACTCAATCAGATTAAGACGATTGTATATGTGTCTTGTGATTTAAAATCACTA
GCAAGAGATATCAATGGCTTAAAAGATTTATATGATATTAAAAAAATCATTCCAGTTAGA
ATGTTTCCGTCCACAATTCATATGGAAACAATTACCTTGCTTTCGTTAAAATAG

>protein sequence
MRLKVKTNDLDYQGQGVTRIDDKVTFIKGMFDDEVGIIEITKSKKNFQQAKLVELIQKNK
QRVSENSFDYAPFFGLSLKAECLWQQKITKETIKKITNLDVEVEDTITDGKKLNYRNKIT
LHVKHIGGSLKIGTYEENSNYLEPIETHHLALPVINDKITVLNKWLKTFKLETNDIKNFT
LRTNGKDVMLIIGIKLKFEGTESIIDELKKHFESIYLNIEKRSFENLSDESIHVYGLETL
KMTFNHLSFEIGPESFFQVNKDVAILMYDEIKKLTQNHTVIDAYAGMASIGQYIDAKKVY
AIESNLDSIIQAKKILKVNQVDHVELIHGQVEEKLEAYIKHADAIVFDPPRSGLTESIIE
LVKLNQIKTIVYVSCDLKSLARDINGLKDLYDIKKIIPVRMFPSTIHMETITLLSLK