ACL_RS02310

Uniprot: A9NFF1
Description: malonyl CoA-ACP transacylase
EC number: 2.3.1.39
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: Malonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier-protein]. {ECO:0000256|PIRNR:PIRNR000446}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site: ACT_SITE 88 88 {ECO:0000256|PIRSR:PIRSR000446-1}.; ACT_SITE 198 198 {ECO:0000256|PIRSR:PIRSR000446-1}.
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): fabD
Gene names (synonym):
Mass: 33,909
Subunit structure [CC]:
Gene ontology (GO): [acyl-carrier-protein] S-malonyltransferase activity [GO:0004314]; metabolic process [GO:0008152]
Gene ontology IDs: GO:0004314; GO:0008152
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the fabD family. {ECO:0000256|PIRNR:PIRNR000446}.
Protein families: FabD family
Coiled coil:
Domain [FT]: DOMAIN 6 297 PKS_AT. {ECO:0000259|SMART:SM00827}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NFF1
MEROPS:
EnsemblBacteria KO: ABX81081
UniPathway: K00645
CDD:
Gene3D:
HAMAP: 3.40.366.10
InterPro:
PANTHER: IPR001227;IPR014043;IPR016035;IPR024925;IPR016036;IPR020801
PIRSF:
PRINTS: PIRSF000446
PROSITE:
Pfam:
ProDom: PF00698
SMART:
SUPFAM: SM00827
TIGRFAMs: SSF52151;SSF55048

487530-488451(+)

>nucleotide sequence
ATGAAAACAGCGATTTTATTTTCTGGTCAAGGTGCTCAATACGTCAACATGGGACTAGAT
TTCATTGAAAATGTTCCAGAGTTAAAGCATAAACTAGAGTCATACGCAGCTATTTTAGAT
TTAGACATCTTATCTCATTTAAAAGATGAAACCAAAATAAATGATACAAGATATACACAA
CCATTAATGGTTGTAGTAGAAATGTTAATCCATGATTACTTAGTATCACAAGGGTTAAAG
ATTGATGGATATGCAGGCTTTTCATTAGGTGAGTTTGCTGGTCTATATGCTGCGGGATTT
TATGAAGCAGAAAACATCTTAAAGATAATTAATATGCGAGCAAAACTTATGCAAGAGGCA
TCTACCCTAAACCCTGGCGCCATGGCAGCTATCTTATCCCTTAGTGATGATGTTGTTGAG
GCAATTTGTAAGGAAGTGTCAACACCAAATGATTTAGTAGTTGCAGCAAACTATAATAGT
GATGGTCAACTTGTTATCTCTGGATCTAAAAAAGCAGTACAGTTAGCTGTAGATTTAGCT
AAAGAAAAAGGTGCTAGAAGAGCGATGATGCTAAATGTATCAGGAGCCTTCCATTCACCT
TATATGAAAGATGCAGGCTCAAGTTTAAAACTTTATGCAGAAAATTTTAAACTTCATGAT
GCTCATAAAGTACTTTATGCCAATACAACAGCAATGCCATTAAAAAAAGAAGATGTTTTA
AATGAAATCTATGAGCAAATAGCAAATCCAGTATATTTCAAACAAACGATTCAACACATG
GTTAAAGATGGATTTGAAAGATTTATTGAAGTCGGTCCAGGTCAAGTACTTTCAAGTTTA
GTTAAAAAAATTAGTCCTGAAAGCAAAATATATAATGTATCCAAATTTGAGGATATAAAA
AATTTAGAGGAGATTTTATAA

>protein sequence
MKTAILFSGQGAQYVNMGLDFIENVPELKHKLESYAAILDLDILSHLKDETKINDTRYTQ
PLMVVVEMLIHDYLVSQGLKIDGYAGFSLGEFAGLYAAGFYEAENILKIINMRAKLMQEA
STLNPGAMAAILSLSDDVVEAICKEVSTPNDLVVAANYNSDGQLVISGSKKAVQLAVDLA
KEKGARRAMMLNVSGAFHSPYMKDAGSSLKLYAENFKLHDAHKVLYANTTAMPLKKEDVL
NEIYEQIANPVYFKQTIQHMVKDGFERFIEVGPGQVLSSLVKKISPESKIYNVSKFEDIK
NLEEIL