ACL_RS02520

Uniprot: A9NFJ1
Description: 3-ketoacyl-CoA thiolase
EC number: 2.3.1.9
Annotation score: 1 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site: ACT_SITE 88 88 Acyl-thioester intermediate. {ECO:0000256|PIRSR:PIRSR000429-1}.; ACT_SITE 357 357 Proton acceptor. {ECO:0000256|PIRSR:PIRSR000429-1}.; ACT_SITE 388 388 Proton acceptor. {ECO:0000256|PIRSR:PIRSR000429-1}.
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): atoB
Gene names (synonym):
Mass: 42,954
Subunit structure [CC]:
Gene ontology (GO): acetyl-CoA C-acetyltransferase activity [GO:0003985]; metabolic process [GO:0008152]
Gene ontology IDs: GO:0003985; GO:0008152
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the thiolase family. {ECO:0000256|RuleBase:RU003557}.
Protein families: Thiolase family
Coiled coil:
Domain [FT]: DOMAIN 4 262 Thiolase_N. {ECO:0000259|Pfam:PF00108}.; DOMAIN 270 400 Thiolase_C. {ECO:0000259|Pfam:PF02803}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NFJ1
MEROPS:
EnsemblBacteria KO: ABX81121
UniPathway: K00626
CDD:
Gene3D:
HAMAP: 3.40.47.10
InterPro:
PANTHER: IPR002155;IPR016039;IPR020615;IPR020610;IPR020617;IPR020613;IPR020616
PIRSF:
PRINTS: PIRSF000429
PROSITE:
Pfam: PS00098;PS00737;PS00099
ProDom: PF02803;PF00108
SMART:
SUPFAM:
TIGRFAMs: SSF53901

526904-528116(+)

>nucleotide sequence
ATGAATAAAGTTTTTGTTGTAGCTGCTAAGAGAAGTGCCATTGGATCTTACTTAGGTACA
TTGTCACAAATCAGTCCAGCAGATTTTGGTTCTCAAGTTTTAAAACAAACATTGGAACTT
AATGACATCAAACCAGAGTGGGTTGATGAAGTTATTATTGGTAATGTACTACCAGCAGGT
CAAAAACAAGGGTTACCAAGACAAATCTCTATCAAAGCAGGTATTTCTCCAGAAGTACCA
GCGTATGGTGTAAATATGATTTGTGGTTCTGGTATGAAATCAGTTATCACAGGTGTTGCA
AACATTAAAGCTGGTTTTGCAAACTTAGTTGTTGCAGGTGGTGTGGAATCTATGTCACAA
GCTCCATATTTAGTACCAGGCACTGTTAGAAACGGTGTAAAAATGGGTAATTTAGAATTG
GTTGACTACATGGTTACAGATGGTCTTTCAGATGCGTTTGAAGGCTATCACATGGGTATT
ACTGCTGAAAACATCGTAGAAAAACATAAATTTACTCGTGAAATGCAAGATGATTTTGCA
TATCACTCACAAGTTAAAGCAAAACAAGCTCAAGAAAAAGGCTTATTTGATAAAGAAATC
GTTCCAGTAAAAATTCAATCTAGAAAAGCTGAAATTGTGTTTGATAAAGATGAATATATC
AATTACACGACTACTAGAGAAAAAATTGCTCAATTACGTCCAGCATTCAAAAAAGATGGA
ACAGTCACTGCAGCAAGTTCATCAGGTATTAATGATGGTGCAAGTTTTATGGTCTTAGCA
AGTGAAGCATTTGTAAAAGAACATAATTTAAAACCATTAGCTGAAATTGTTGGTGTTGGT
CAAGCTGGTGTTGAACCAAGCGTTATGGGTTTAGGACCTGTACCTGCAATTAAAAATTCA
TTAAAACAAGCGAACCTTAAGATTAGTGATATTGATACATTTGAATTAAACGAAGCATTT
GCAGCACAAGCATTAGGTGTTGTACGTGAACTTTCTGAAGATTTAGGTATTAAAGAATCA
GCAATCTTAGATAAAACAAATCCAAATGGTGGTGCGATCGCGTTAGGTCACCCAGTTGGA
GCATCAGGTAATAGAATCATGGTTACACTATTACATAATATGTTAAGAAATGAAAACCAT
AATATTGGTTTAGCAAGTCTATGTATCGGTGGCGGTATGGGAACATCTGTCATCTTTAAA
AAAGTTAAATAA

>protein sequence
MNKVFVVAAKRSAIGSYLGTLSQISPADFGSQVLKQTLELNDIKPEWVDEVIIGNVLPAG
QKQGLPRQISIKAGISPEVPAYGVNMICGSGMKSVITGVANIKAGFANLVVAGGVESMSQ
APYLVPGTVRNGVKMGNLELVDYMVTDGLSDAFEGYHMGITAENIVEKHKFTREMQDDFA
YHSQVKAKQAQEKGLFDKEIVPVKIQSRKAEIVFDKDEYINYTTTREKIAQLRPAFKKDG
TVTAASSSGINDGASFMVLASEAFVKEHNLKPLAEIVGVGQAGVEPSVMGLGPVPAIKNS
LKQANLKISDIDTFELNEAFAAQALGVVRELSEDLGIKESAILDKTNPNGGAIALGHPVG
ASGNRIMVTLLHNMLRNENHNIGLASLCIGGGMGTSVIFKKVK