ACL_RS02525

Uniprot: A9NFJ2
Description: short-chain dehydrogenase
EC number: 1.1.1.100
Annotation score: 1 out of 5
Miscellaneous [CC]:
Protein existence: Evidence at protein level
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site: BINDING 18 18 NAD; via amide nitrogen. {ECO:0000213|PDB:4NBT}.; BINDING 37 37 NAD. {ECO:0000213|PDB:4NBT}.; BINDING 81 81 NAD; via carbonyl oxygen. {ECO:0000213|PDB:4NBT}.; BINDING 146 146 NAD. {ECO:0000213|PDB:4NBT}.; BINDING 150 150 NAD. {ECO:0000213|PDB:4NBT}.
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding: NP_BIND 54 55 NAD. {ECO:0000213|PDB:4NBT}.; NP_BIND 178 183 NAD. {ECO:0000213|PDB:4NBT}.
Site:
Gene names (primary): fabG2
Gene names (synonym):
Mass: 25,509
Subunit structure [CC]:
Gene ontology (GO): 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; nucleotide binding [GO:0000166]
Gene ontology IDs: GO:0000166; GO:0004316; GO:0102132
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities:
Protein families:
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NFJ2
MEROPS:
EnsemblBacteria KO: ABX81122
UniPathway: K00059
CDD:
Gene3D:
HAMAP: 3.40.50.720
InterPro:
PANTHER: IPR016040;IPR020904;IPR002347
PIRSF:
PRINTS:
PROSITE: PR00081;PR00080
Pfam: PS00061
ProDom:
SMART:
SUPFAM:
TIGRFAMs: SSF51735

528130-528853(+)

>nucleotide sequence
ATGAAAAAACTAGAAGGTAAAGTTGCAGTTATTACAGGTGGTGCAAAAGGTTTAGGACAA
GCAATCGCTTTAGCTTATGCTGAAGAAGGTGCAAAAGTAATCGCAGGTGATTTAGGTGAT
CTAACTTATTCACATCCAAATGTTGAAGGCATGTATTTAAACGTTACTGATGTAACAGGC
GTTGAAAAATTCTACCAATCAGTGATTGACAAATATGGTAAAATCGATATTTTAGTAAAT
AATGCTGGTATCACTAAAGATGCTATGACAAGAAAAATGACTGAAGCACAATGGGATGCA
GTTATTGATGTGAACTTAAAAGGTGTATTTAACTTAACTAGATTAGTTGGACCTCAAATG
CAAACTAATGGTTATGGTTCAATTATCAATATTTCATCAGTAGTTGGTGTATTTGGTAAT
ATTGGACAAGCAAACTACGCTGCTACTAAAGCAGGTGTTATTGGTTTAACAATGACTTGG
GCTAAAGAATTTGCGCTTAAAGGTGCAAACGTGCGTGTAAACGCAATCGCTCCAGGATAT
ATCATGACAGATATTTTAAAAACAGTACCACAAGATTTACTAGATAAATTTGCAGCTTTA
ACCATGTTAAATCGTTTAGGTCAACCAGAAGAAATCGCAAAAGTAGCATTATTCCTAGCA
AGTGATGATGCATCTTACGTAACTGGTCAAACGATTAACGTTAACGGCGGCATGAGACTA
TAA

>protein sequence
MKKLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGDLTYSHPNVEGMYLNVTDVTG
VEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGVFNLTRLVGPQM
QTNGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVRVNAIAPGY
IMTDILKTVPQDLLDKFAALTMLNRLGQPEEIAKVALFLASDDASYVTGQTINVNGGMRL