ACL_RS02650

Uniprot: A9NFL6
Description: glycogen phosphorylase
EC number: 2.4.1.1
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: ((1->4)-alpha-D-glucosyl)(n) + phosphate = ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate. {ECO:0000256|RuleBase:RU000587}.
Cofactor: COFACTOR: Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; Evidence={ECO:0000256|RuleBase:RU000587};
Enzyme regulation:
Function [CC]: FUNCTION: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. {ECO:0000256|RuleBase:RU000587}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): glgP
Gene names (synonym):
Mass: 91,863
Subunit structure [CC]:
Gene ontology (GO): glycogen phosphorylase activity [GO:0008184]; pyridoxal phosphate binding [GO:0030170]; carbohydrate metabolic process [GO:0005975]
Gene ontology IDs: GO:0005975; GO:0008184; GO:0030170
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the glycogen phosphorylase family. {ECO:0000256|RuleBase:RU004179}.
Protein families: Glycogen phosphorylase family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NFL6
MEROPS:
EnsemblBacteria KO: ABX81146
UniPathway: K00688
CDD:
Gene3D:
HAMAP:
InterPro:
PANTHER: IPR011833;IPR000811
PIRSF: PTHR11468
PRINTS: PIRSF000460
PROSITE:
Pfam: PS00102
ProDom: PF00343
SMART:
SUPFAM:
TIGRFAMs:

558850-561229(+)

>nucleotide sequence
ATGGACAACGTATTTATTAACAAAGAGATTTTTAAGGGTGCATATATACTCATGCTAAAG
AATCTATTCAATAAAAGAATAGAAACAGCAACATTATATGAAAAGTATGCAGCATTAGCT
TCATTACTTGATAAACAACTAGAGAATGACTACGAAGCAACTACGGAATATGTAGAGAAA
AACAATCTAAAGAAAACTATTTATTTTTCAATGGAGTTCTTAATGGGTCGTTTGATCACA
TCTAACCTCATGAACTCAGGTTATGCGGATGTTGTAAAAGCAGCATTTGATGATTTTGGA
TATGATTTAAATGAAATTGAACTTGCAGAAACAGATGCAGGACTTGGTAATGGAGGATTA
GGTCGATTAGCGGCTTGTTTCCTTGATTCAGCAGCATCATTATCATTACCTTTTTATGGT
AATTCACTAAGATATAAAAAAGGATTCTTTGTTCAAAGATTCGAAAACGACAAACAAAGA
GAATATCCAGACCCTTGGTTAGATAAACCATTTTATTGGGAAGAAAGAAAAGAACAAGAA
GCTATCCACATTCCATATTTTGGTTATGTAAAAGATACTAAATTAATTGATCCTGTATGG
GTTAAAGCTGTACCTTATGATGTTAAAGTTGTTGGTGCTGGTAATGGTGTAATTACGCAT
CTTAGATTATGGTCAGCTGAAAAGAGTGAATTACATCCATATCATGATGAAGAATATCTA
AAAATGGTTTCTAAAATCACTGAATCATTATACCCAGATGACTCTACTGAAGCGGGGAAA
ACATTAAGATTACAACAACAATACCTATTCTCAGCAGCAGGTATTAAATCAGTTATTTTA
GAGCATAAACGTTTAGGTCGTGATATTAAAGACTTACATAAATATTATGTATTCCAAGTA
AATGACACCCACCCAACATTAATTATTCCTGAATTAATGCGTATCTTAATGGATGAAGAA
AACTTAGGTTATGATGAATCATGGGATATTGTGACACAATCAGTAGCATATACAAACCAT
ACAATTTTATCTGAAGCATTAGAAAAATGGAATATTAAGATCTTTAGAAACTTATTACCT
AGAGCATTTGAGATCGTTCAAGAAATGAACCGTCGTTTCAAAATTGTTTTAGAAGAAGCT
AAAGTACCACAAGAAAAAATATATCAAATGCAATTAATTGGTGCTAACAATGTACGTATG
GCAAATATTTGTATCTACGGATCGTTTTCAGTGAACGGTGTTGCTGCATTACATACTGAT
ATTTTAAAGAACATTGAACTTAATGACTTCTATAAATTATATCCATCTAAATTTAATAAT
AAGACTAACGGCATTACCCACCGTAGATGGTTATTACATATCAACCATGAATTAACTGAT
ATACTTGATAACTTATTAGGCAGCAAAGCATGGCATAAAGACTTAAGTTTAATTAAAGGA
CTAGAACAATTTAAAGATGATCTAAAAGTCCAAAAAATGATTAAAGACATGAAGTTATCT
AAGAAACGTGCACTCATTCAAAAGATCAAAAAAGATACAGGTATACTTCTTGATGAAAAT
GCTATTTTTGACATTCAAATCAAACGTCTACACGAGTATAAACGTCAATTACTAAATATC
TTGAATATTATTTATACATATCAAAGACTAAAAACAGACATGGAATTCAAAAAGAATTTC
CATCCACAAAACTTTATCTTTGGTGCTAAAGCAGCACCTTCATATGTGATGGCTAAAGGT
ATTATTGAATTAATTAATAAAACGAGCCATGTCATAAATAATGATACCGATACAAACAAG
TTACTTAAAGTTGTCTTTGTAGAAAACTATAATGTAACTTATGCTGAATACTTATTTCCA
GCTGCAGATTTATCTGAACAAATTTCTACTGCATCTAAAGAAGCAAGTGGAACAGGTAAT
ATGAAGTTCATGCTAAATGGTGCTGTAACCATTGGTACAATGGACGGTGCAAACGTAGAA
ATTGTTAAAGAAGCAGGTATGGAAAATAACATCATCTTTGGTTTATCCTCAGATGAGGTA
AATAGCATCTATAAAAACAACGGATACAAACCTAGACAAATTTATGATGAGGATCCAAGA
TTACAATCTATATTTGATTTTATTAGAGGATTAACGATTAATCCGACACACTTTGACTTT
ATCTTACAAAACCTATTAACATCTGACTACTTCCTAGTATTAAAGGATTTTGATAGTTAC
GTTAAAGCACAAGAAAGAGCAAATCAATTATATAAAGACCAAAAACAATGGTGGCATATG
GTTATCATGAATATTGCAAATGCTGGCTTCTTTACATCTGATCGTACGATTGCACAATAC
AATCAAGACATCTGGCAACTAGAAGAAATCAAAAAATAA

>protein sequence
MDNVFINKEIFKGAYILMLKNLFNKRIETATLYEKYAALASLLDKQLENDYEATTEYVEK
NNLKKTIYFSMEFLMGRLITSNLMNSGYADVVKAAFDDFGYDLNEIELAETDAGLGNGGL
GRLAACFLDSAASLSLPFYGNSLRYKKGFFVQRFENDKQREYPDPWLDKPFYWEERKEQE
AIHIPYFGYVKDTKLIDPVWVKAVPYDVKVVGAGNGVITHLRLWSAEKSELHPYHDEEYL
KMVSKITESLYPDDSTEAGKTLRLQQQYLFSAAGIKSVILEHKRLGRDIKDLHKYYVFQV
NDTHPTLIIPELMRILMDEENLGYDESWDIVTQSVAYTNHTILSEALEKWNIKIFRNLLP
RAFEIVQEMNRRFKIVLEEAKVPQEKIYQMQLIGANNVRMANICIYGSFSVNGVAALHTD
ILKNIELNDFYKLYPSKFNNKTNGITHRRWLLHINHELTDILDNLLGSKAWHKDLSLIKG
LEQFKDDLKVQKMIKDMKLSKKRALIQKIKKDTGILLDENAIFDIQIKRLHEYKRQLLNI
LNIIYTYQRLKTDMEFKKNFHPQNFIFGAKAAPSYVMAKGIIELINKTSHVINNDTDTNK
LLKVVFVENYNVTYAEYLFPAADLSEQISTASKEASGTGNMKFMLNGAVTIGTMDGANVE
IVKEAGMENNIIFGLSSDEVNSIYKNNGYKPRQIYDEDPRLQSIFDFIRGLTINPTHFDF
ILQNLLTSDYFLVLKDFDSYVKAQERANQLYKDQKQWWHMVIMNIANAGFFTSDRTIAQY
NQDIWQLEEIKK