ACL_RS02990

Uniprot: A9NFT7
Description: methionine adenosyltransferase
EC number: 2.5.1.6
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): metK2
Gene names (synonym):
Mass: 41,592
Subunit structure [CC]: SUBUNIT: Homotetramer. {ECO:0000256|RuleBase:RU000542}.
Gene ontology (GO): cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; S-adenosylmethionine biosynthetic process [GO:0006556]
Gene ontology IDs: GO:0004478; GO:0005524; GO:0005737; GO:0006556; GO:0046872
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the AdoMet synthase family. {ECO:0000256|RuleBase:RU004462}.
Protein families: AdoMet synthase family
Coiled coil:
Domain [FT]: DOMAIN 3 78 S-AdoMet_synt_N. {ECO:0000259|Pfam:PF00438}.; DOMAIN 104 219 S-AdoMet_synt_M. {ECO:0000259|Pfam:PF02772}.; DOMAIN 221 360 S-AdoMet_synt_C. {ECO:0000259|Pfam:PF02773}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NFT7
MEROPS:
EnsemblBacteria KO: ABX81217
UniPathway: K00789
CDD:
Gene3D:
HAMAP:
InterPro:
PANTHER: IPR022631;IPR022630;IPR022629;IPR022628;IPR002133;IPR022636
PIRSF: PTHR11964
PRINTS: PIRSF000497
PROSITE:
Pfam: PS00376;PS00377
ProDom: PF02773;PF02772;PF00438
SMART:
SUPFAM:
TIGRFAMs: SSF55973

631893-633042(+)

>nucleotide sequence
ATGAAAATTATAACAAGTGAATCTGTCTTTAAAGGACACCCAGATAAAATATGTGACCAA
ATCAGTGATGCAATCTTAGATGCACATTTAGAGCAAGACAGAAATGCAAGAGTAGCAGTA
GAAACAGCTATCAAAGATGATGTTGTTTTTATCTTTGGTGAGGTCACATCCAAAGCTTCA
GTGAATTATAAAGAAGTCGCACTAACCACATTAAAAGAAATCGGATATGATGATCCATTC
GATGTGATTGAAAAGATATCCAAACAGTCCGATGATATTGCACTTGGTGTAAATCATACG
AACGATCATGAACAAGGTGCAGGTGATCAAGGCTTAATGTTTGGCTACGCTTGCAAAGAA
ACGCCAGAATTTATGCCTTTACCGATTGTGGTGGCACATGACATTGCAAGAAGCATTGAC
GAGCTTAGAAAGGCAAAGTATGGCCACGTGTTTGGTCCAGATGGTAAGTGTCAAGTTTCT
GTAGTCTACGAGAATGATGAACCGATTGCTTATGAAACAATCGTAGTGTCTGCGCAAACA
AAGCATGGCATTCAATTAGATTATGCTAAAGAGATAATTTTAAATGAAGTATTGAAACTA
CTGATAGGTGAAGACCTTTCACACATTCAAGTCTTAATCAATCCAACAGGTGCTTTTGTC
GTTGGTGGACCATATGGAGATTCTGGATTAACTGGTAGAAAGATTATTGTTGATACCTAT
GGTGGTTATGCTAAACATGGCGGTGGCGCATTCTCTGGCAAGGATGTGAGCAAGGTAGAC
CGCAGTGCGGCTTACTATGCCAGATTCGTAGCAAAAGCCCTTGTAGCGGCAAATTTAGCG
AACAGGTGCGAAGTTAGTGTGTCCTATTCCATCGGTGTAGCAAACCCTGTAAGTGTATCC
GTTGATACCTTTGGAACAGGTGTTACTTCTGATGATGTTTTATTAAAGTTAATTAAAGAG
AACTTCAACTTTACACCGTCAAGTATTATCAAAGAACTAAACCTGGACAAAGTGAAGTTT
AAACCGTTAGCATCTTATGGACATATAGGTCGTGTTGATCTTGATGTTGCATGGGAAAAA
GTAGATGCAAAAGCTAAACAATTAAGTGAATCTTATGAGCAAACCAAAAGAACTGCACAG
GTTCTATAA

>protein sequence
MKIITSESVFKGHPDKICDQISDAILDAHLEQDRNARVAVETAIKDDVVFIFGEVTSKAS
VNYKEVALTTLKEIGYDDPFDVIEKISKQSDDIALGVNHTNDHEQGAGDQGLMFGYACKE
TPEFMPLPIVVAHDIARSIDELRKAKYGHVFGPDGKCQVSVVYENDEPIAYETIVVSAQT
KHGIQLDYAKEIILNEVLKLLIGEDLSHIQVLINPTGAFVVGGPYGDSGLTGRKIIVDTY
GGYAKHGGGAFSGKDVSKVDRSAAYYARFVAKALVAANLANRCEVSVSYSIGVANPVSVS
VDTFGTGVTSDDVLLKLIKENFNFTPSSIIKELNLDKVKFKPLASYGHIGRVDLDVAWEK
VDAKAKQLSESYEQTKRTAQVL