ACL_RS03230

Uniprot: A9NFY3
Description: RNA pseudouridine synthase
EC number: 5.4.99.-
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): rsuA1
Gene names (synonym):
Mass: 26,933
Subunit structure [CC]:
Gene ontology (GO): pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; pseudouridine synthesis [GO:0001522]
Gene ontology IDs: GO:0001522; GO:0003723; GO:0009982
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the pseudouridine synthase RsuA family. {ECO:0000256|RuleBase:RU003887, ECO:0000256|SAAS:SAAS00545889}.; SIMILARITY: Contains S4 RNA-binding domain. {ECO:0000256|SAAS:SAAS00568442}.
Protein families: Pseudouridine synthase RsuA family
Coiled coil:
Domain [FT]: DOMAIN 1 66 S4 RNA-binding. {ECO:0000259|PROSITE:PS50889}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NFY3
MEROPS:
EnsemblBacteria KO: ABX81263
UniPathway: K06183
CDD:
Gene3D:
HAMAP: 3.10.290.10
InterPro:
PANTHER: IPR020103;IPR000748;IPR018496;IPR006145;IPR002942
PIRSF:
PRINTS:
PROSITE:
Pfam: PS01149;PS50889
ProDom: PF00849;PF01479
SMART:
SUPFAM: SM00363
TIGRFAMs: SSF55120

674652-675363(-)

>nucleotide sequence
CTAATGGTTAATTTTATCGTTTAATTCTTTTAATTCGTCACTTGTTAGATAACGCCAATA
ACCAACTGGTAAATCACCTAAGGTTAAGTGCATAATTCTAACACGTTCAAGCGATTCAAC
ACGGTAACCTAAACTATCTGCCATACGTCTAATTTGACGGTTTAATCCTTGTCTAATGGT
AAGACTGAAAGTTCTTTCATCTAATGGTTTTAAAATAGATGGCATGGTCATTTGTTTTTC
ATGAGCAACTGGATTATAGATTTCTACACCAGATGTCATTGTTTCAATGAAGTAGTCATC
ATAAGGTTTATTTAATGTGACATGATATTCTTTATCATGTCCATTTTCTACTCTTAATAT
TTTATTGACGATACTACCATCATTGGTAAGTAGAATAAGACCATGTGAGTCTTTATCTAA
TCTACCAACAGGAAATATTTTTTCTTTAAAATTCATGAAAGTGATCATATTACCAGAAAT
TGCTGTATTTGTAGTAGAAACAATACCTACAGGTTTATTAAGTAGAATATAGAATTTTTC
TTCTAAGGGTTCGATGATGTTGTTATCTAAGGTAACGACATCATTTTTTGTTATTTGCAT
GCCTAACACGGCTGTTACGCCGTTGACCTTAATGCGTCCGTGCTCAATTAAACTGTCAGC
ACCACGACGAGATGCAACCCCAGTTTTAGAGATGTAAAGGTTTAAGCGCAT

>protein sequence
MRLNLYISKTGVASRRGADSLIEHGRIKVNGVTAVLGMQITKNDVVTLDNNIIEPLEEKF
YILLNKPVGIVSTTNTAISGNMITFMNFKEKIFPVGRLDKDSHGLILLTNDGSIVNKILR
VENGHDKEYHVTLNKPYDDYFIETMTSGVEIYNPVAHEKQMTMPSILKPLDERTFSLTIR
QGLNRQIRRMADSLGYRVESLERVRIMHLTLGDLPVGYWRYLTSDELKELNDKINH