ACL_RS03380

Uniprot: A9NG15
Description: site-specific tyrosine recombinase XerD
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site: ACT_SITE 147 147 {ECO:0000256|HAMAP-Rule:MF_01808}.; ACT_SITE 171 171 {ECO:0000256|HAMAP-Rule:MF_01808}.; ACT_SITE 242 242 {ECO:0000256|HAMAP-Rule:MF_01808}.; ACT_SITE 245 245 {ECO:0000256|HAMAP-Rule:MF_01808}.; ACT_SITE 268 268 {ECO:0000256|HAMAP-Rule:MF_01808}.; ACT_SITE 277 277 O-(3'-phospho-DNA)-tyrosine intermediate. {ECO:0000256|HAMAP-Rule:MF_01808}.
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): xerD
Gene names (synonym): xerC
Mass: 34,641
Subunit structure [CC]: SUBUNIT: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD. {ECO:0000256|HAMAP-Rule:MF_01808, ECO:0000256|SAAS:SAAS00608017}.
Gene ontology (GO): cytoplasm [GO:0005737]; DNA binding [GO:0003677]; tyrosine-based site-specific recombinase activity [GO:0009037]; cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; transposition, DNA-mediated [GO:0006313]
Gene ontology IDs: GO:0003677; GO:0005737; GO:0006313; GO:0007049; GO:0007059; GO:0009037; GO:0051301
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities:
Protein families:
Coiled coil:
Domain [FT]: DOMAIN 5 89 Integrase_SAM-like_N. {ECO:0000259|Pfam:PF02899}.; DOMAIN 111 281 Phage_integrase. {ECO:0000259|Pfam:PF00589}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NG15
MEROPS:
EnsemblBacteria KO: ABX81295
UniPathway: K04763
CDD:
Gene3D:
HAMAP: 1.10.150.130;1.10.443.10
InterPro: MF_01808
PANTHER: IPR011010;IPR013762;IPR002104;IPR023109;IPR004107;IPR011932;IPR023009
PIRSF:
PRINTS:
PROSITE:
Pfam:
ProDom: PF02899;PF00589
SMART:
SUPFAM:
TIGRFAMs: SSF56349

713247-714153(+)

>nucleotide sequence
ATGACCTATTTAATCAAAGATTTTTCTTATTATTTGAATAATGAATTGGGTTTATCCAAG
AATACCATTGATGCATATATGAGAGATTTAAAGGACTATGAATCTTTCTTAGATAAATAT
CATAAATTAAAAGATGTAGATAACATTCAATCAAAGCACATTGAAGGTTATCTTAAAAGT
ATTAAGAAAAAGGGATTATCTGCTAAAACGATATCTAGAAAACTCACCTCAATTAAATCA
TTTCATAAGTTTTTACTGATGGAAAAAGAAGTGGATGAAGATGTTACGCATAAAATTGCT
AGACCTAAAATAGAAAAAACTTTACCTACAGTATTAAGTGTAGATGAGGTAATTAGTATA
TTAGAAGTCATAGATAAGTCCACGACATTGGGTTTAAGAAATATGGCATTGCTAGAACTT
ATATACGGTTCTGGACTGCGTGTTTCTGAATTACTTAATATAAAATTAAAGGATATCCAT
ATGCAACAAAGCTATGTTATTGTCACTGGTAAAGGGTCAAAAGAACGTATGGTACCTATA
TCGGATATGGCAATTATAGCAATTAGAAATTATTTAGTTAAGGCTAGAGATGATTTGATT
AAGGAAAAAACAGATTATTTATTTATTAATAATCAAGGTAAAACACTTTCACGTGTAGGC
TTTTTTAAAGTCTTAAAAAAGCTTGCAAGCGAAGCAAATTTAGACCCTGAAAAAGTGTCA
CCACATACCTTAAGGCATTCATTTGCAACACACCTTTTAGAGAATGGAATGGATTTAAGA
AGTCTTCAAAACCTACTTGGCCATGAAGATATATCGACTACACAAATCTATACACACATC
TCACAATCAAGATTAAAACAAGTTTATAACAAAACTCATCCAAGAGCAAAGGAGAATAAC
AAATGA

>protein sequence
MTYLIKDFSYYLNNELGLSKNTIDAYMRDLKDYESFLDKYHKLKDVDNIQSKHIEGYLKS
IKKKGLSAKTISRKLTSIKSFHKFLLMEKEVDEDVTHKIARPKIEKTLPTVLSVDEVISI
LEVIDKSTTLGLRNMALLELIYGSGLRVSELLNIKLKDIHMQQSYVIVTGKGSKERMVPI
SDMAIIAIRNYLVKARDDLIKEKTDYLFINNQGKTLSRVGFFKVLKKLASEANLDPEKVS
PHTLRHSFATHLLENGMDLRSLQNLLGHEDISTTQIYTHISQSRLKQVYNKTHPRAKENN
KW