ACL_RS03435

Uniprot: A9NG26
Description: dihydrofolate reductase
EC number: 1.5.1.3
Annotation score: 1 out of 5
Miscellaneous [CC]:
Protein existence: Predicted
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): folA
Gene names (synonym):
Mass: 18,291
Subunit structure [CC]:
Gene ontology (GO): dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; nucleotide biosynthetic process [GO:0009165]
Gene ontology IDs: GO:0004146; GO:0006545; GO:0009165; GO:0050661
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities:
Protein families:
Coiled coil:
Domain [FT]: DOMAIN 1 156 DHFR (dihydrofolate reductase). {ECO:0000259|PROSITE:PS51330}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NG26
MEROPS:
EnsemblBacteria KO: ABX81306
UniPathway: K00287
CDD:
Gene3D: cd00209
HAMAP: 3.40.430.10
InterPro:
PANTHER: IPR012259;IPR024072;IPR001796
PIRSF:
PRINTS:
PROSITE: PR00070
Pfam: PS51330
ProDom: PF00186
SMART:
SUPFAM:
TIGRFAMs: SSF53597

723354-723825(-)

>nucleotide sequence
TCAAATCTCTTTCTTATATGTTGCAAATATTAAACTAGGTGCTAACTTTTTATCAACTAA
TTTGTAGCTAGATAAGTCAAAATGGTTGAAGTATACATTACCTTTATGAATGTCTAGTAC
GTGGGTGATTAATAAATAATCAACATAAGGTAAGGTTAGGTTATAAATAACTTTACCACC
AATGATCCATAGTTCATCTTTATAGTTTTTAACAAAATCCACTACATCTGTGATGCATTC
TGCATCATCATAAGCCGTATCAATGAGGTTAGCTACATAAATTTTACCGTATGGAAAAGG
TTTATCTTTATAATAACCTTTCAGTGATTTATAAGTTAAATCACCCATTAATACAGTTTT
ACCTTTAGTTTTTTCTTTAAAATACGCCAAGTCTTCTTTATAGTGCCAAGCAAGCTTATT
ATCTTGACCTATAAGCCAATTGACATCCATTGCCCAAATTGCGTAAATCAT

>protein sequence
MIYAIWAMDVNWLIGQDNKLAWHYKEDLAYFKEKTKGKTVLMGDLTYKSLKGYYKDKPFP
YGKIYVANLIDTAYDDAECITDVVDFVKNYKDELWIIGGKVIYNLTLPYVDYLLITHVLD
IHKGNVYFNHFDLSSYKLVDKKLAPSLIFATYKKEIW