ACL_RS03490

Uniprot: A9NG37
Description: 5'/3'-nucleotidase SurE
EC number: 3.1.3.5
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate. {ECO:0000256|HAMAP-Rule:MF_00060, ECO:0000256|SAAS:SAAS00165042}.
Cofactor: COFACTOR: Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; Evidence={ECO:0000256|HAMAP-Rule:MF_00060}; ; Note=Binds 1 divalent metal cation per subunit. {ECO:0000256|HAMAP-Rule:MF_00060}
Enzyme regulation:
Function [CC]: FUNCTION: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. {ECO:0000256|HAMAP-Rule:MF_00060}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding: METAL 8 8 Divalent metal cation. {ECO:0000256|HAMAP-Rule:MF_00060}.; METAL 9 9 Divalent metal cation. {ECO:0000256|HAMAP-Rule:MF_00060}.; METAL 39 39 Divalent metal cation. {ECO:0000256|HAMAP-Rule:MF_00060}.; METAL 95 95 Divalent metal cation. {ECO:0000256|HAMAP-Rule:MF_00060}.
Nucleotide binding:
Site:
Gene names (primary): surE
Gene names (synonym):
Mass: 26,868
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
Gene ontology IDs: GO:0000166; GO:0005737; GO:0008253; GO:0046872
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the SurE nucleotidase family. {ECO:0000256|HAMAP-Rule:MF_00060, ECO:0000256|SAAS:SAAS00534723}.
Protein families: SurE nucleotidase family
Coiled coil:
Domain [FT]: DOMAIN 3 183 SurE. {ECO:0000259|Pfam:PF01975}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: ABX81317
UniPathway: K03787
CDD:
Gene3D:
HAMAP: 3.40.1210.10
InterPro: MF_00060
PANTHER: IPR030048;IPR002828
PIRSF:
PRINTS:
PROSITE:
Pfam:
ProDom: PF01975
SMART:
SUPFAM:
TIGRFAMs: SSF64167

732185-732917(-)

>nucleotide sequence
TTATGAATTAAATAACTTTTCAATCTTTTTATAATCTGTTCTATCCATTTTTAATGGGGT
TATTGAAACATAACCTTCATTAAATGCAGTCATATCAGCATCTTCATCTTCTTTAACAAA
GATATTAGATCCTAATATTCTATATGTATTTGGTTTATCCGTTTTAATGAATTCAGAGTG
TTGAATTCTTAAACCCATTTTAGTAATACGTGTACCAAGTACTTTTTTAAAGGATGCATG
TGGATAGTTAATATTTAATATATCTGTTTCTAAATATAATTTATTTTCAATGATTTCATC
TAATAATTTGATGGTTTCATCAAATATATAAGGTAATTTGATGTCAGGTGCTGAAAAAGC
TATTGCATTTAACCCCATAATAGAAGCTTCAAAAGCTGCAGCTACTGTACCAGAGTATTG
AACATCAATGGCTAAATTGACACCATCATTAATGCCTGATACGACAAGATCAAATTCTTG
TTCAAAGACTTTCACGCCTAATCTAACACAGTCTGCAGGTGTTCCATCAACAACGATTGT
TCTTACACTGCCCAATACTGGTTCAATCTCCTCAACTTCAATATAACCTGTATAGGTAAT
GGATGCTGATTTTGCAGATTGTTGAACTTTTGGTGCTGAGACATAGACACTTCCGTGATA
GCTTGCTGCCTTTGTTAATATATGTAAACCTTCTGCATCAATTCCATCATCATTGACTAC
TAAAATGTTCAT

>protein sequence
MNILVVNDDGIDAEGLHILTKAASYHGSVYVSAPKVQQSAKSASITYTGYIEVEEIEPVL
GSVRTIVVDGTPADCVRLGVKVFEQEFDLVVSGINDGVNLAIDVQYSGTVAAAFEASIMG
LNAIAFSAPDIKLPYIFDETIKLLDEIIENKLYLETDILNINYPHASFKKVLGTRITKMG
LRIQHSEFIKTDKPNTYRILGSNIFVKEDEDADMTAFNEGYVSITPLKMDRTDYKKIEKL
FNS