ACL_RS03515

Uniprot: A9NG42
Description: cell division protein FtsZ
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. {ECO:0000256|HAMAP-Rule:MF_00909, ECO:0000256|RuleBase:RU000631}.
Pathway:
Active site:
Binding site: BINDING 140 140 GTP. {ECO:0000256|HAMAP-Rule:MF_00909}.; BINDING 144 144 GTP. {ECO:0000256|HAMAP-Rule:MF_00909}.; BINDING 188 188 GTP. {ECO:0000256|HAMAP-Rule:MF_00909}.
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding: NP_BIND 109 111 GTP. {ECO:0000256|HAMAP-Rule:MF_00909}.
Site:
Gene names (primary): ftsZ
Gene names (synonym):
Mass: 39,970
Subunit structure [CC]:
Gene ontology (GO): cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]
Gene ontology IDs: GO:0003924; GO:0005525; GO:0005737; GO:0032153; GO:0043093; GO:0051258
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the FtsZ family. {ECO:0000256|HAMAP-Rule:MF_00909, ECO:0000256|RuleBase:RU000631}.
Protein families: FtsZ family
Coiled coil:
Domain [FT]: DOMAIN 14 206 Tubulin. {ECO:0000259|SMART:SM00864}.; DOMAIN 208 324 Tubulin_C. {ECO:0000259|SMART:SM00865}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NG42
MEROPS:
EnsemblBacteria KO: ABX81322
UniPathway: K03531
CDD:
Gene3D:
HAMAP: 3.30.1330.20;3.40.50.1440
InterPro: MF_00909
PANTHER: IPR000158;IPR020805;IPR024757;IPR008280;IPR018316;IPR003008
PIRSF:
PRINTS:
PROSITE: PR00423
Pfam: PS01134;PS01135
ProDom: PF12327;PF00091
SMART:
SUPFAM: SM00864;SM00865
TIGRFAMs: SSF52490;SSF55307

737886-739008(-)

>nucleotide sequence
TTATTTTCTATGTAGCCAAGAAGGTAATGTACGCTTCTTAGTATCTTCACCAGATGCTTC
CTTATTATTTAAAGGCTCTAATCCAGTATCTGTTATTTTTACTTGTTGTGTGCTGTTGTT
TCTAAAGATGTCACCAGCAATCTTTTCAACTTCATTGCCTTTAGCACGAAGTTCATAACC
GGTTGCAACGATTGTAACAATCATTTCATCTTCTAAGTCAACACTGACTGTATGTCCGTA
AATAACGTTTAAATCGGACTCAGTTGCATTTCTAATTTCAGTTAATGCTGCTTCAATTTC
AAATAATGTCACTTCAGCCCCAGAAGAGATATTTACGATCGCATCTGTTGCACCATCAAT
GGATACTTCTAATAATTTGGAATGGATTGCTTTTCTAGCTGCTTCAATCGCACGGTTTTC
ACCACTAGCCATACCAATACCCATTAAGGCTGTACCTTTATTTTCCATCACAGTTCTAAC
GTCAGCAAAGTCAACATTGATCATACCAGGAACTGCAATAATTTCAGCAATACCTTGTAC
ACCTTGACGTAATACTTTATCAGATTCTCTAAATGCATCTAGTAATTGCATATCTCTATC
AGCAATTGAGAATAATCTTTCATTTGGTATCACAATTAAAGTGTCAACATTTGGTTTTAA
CTCTTCAAGTCCAGTAATTGCATGTTGCATACGAAGTGGACCTTCAAATACGAATGGTTT
TGTTACGATACCGATTGTAAGAACGCCAAGTTCTTTAGCAATACGTGCAACCACAGGTGC
TGCACCAGTACCAGTTCCACCACCCATACCAGCAGTAATAAAAACCATATCTGCATCAGA
TAGTACTTCTCTAATATCATCCTCAGATTCGAGTGCTGCTTGCTTACCAATAGCTGGTTT
AGCGCCTGCACCTAATCCTCGAGTCAACTTCTTACCTAATTGAATACGCTCATCTGCTTT
GGATACTTTAAGTACCTGAGCATCCGTATTCATCGCTACATATGAAACCCCTCTAACATC
ATTTTCAATCATGCGGTTTACTGCAGAGTTGCCTCCACCACCGACACCGATGACCTTGAT
AACGGGCTTTTGATTAAATTCATCGTTAAATCCAAAAACCAT

>protein sequence
MVFGFNDEFNQKPVIKVIGVGGGGNSAVNRMIENDVRGVSYVAMNTDAQVLKVSKADERI
QLGKKLTRGLGAGAKPAIGKQAALESEDDIREVLSDADMVFITAGMGGGTGTGAAPVVAR
IAKELGVLTIGIVTKPFVFEGPLRMQHAITGLEELKPNVDTLIVIPNERLFSIADRDMQL
LDAFRESDKVLRQGVQGIAEIIAVPGMINVDFADVRTVMENKGTALMGIGMASGENRAIE
AARKAIHSKLLEVSIDGATDAIVNISSGAEVTLFEIEAALTEIRNATESDLNVIYGHTVS
VDLEDEMIVTIVATGYELRAKGNEVEKIAGDIFRNNSTQQVKITDTGLEPLNNKEASGED
TKKRTLPSWLHRK