ACL_RS03710

Uniprot: A9NG83
Description: peptidyl-prolyl cis-trans isomerase
EC number: 5.2.1.8
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: Peptidylproline (omega=180) = peptidylproline (omega=0). {ECO:0000256|RuleBase:RU363019}.
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. {ECO:0000256|RuleBase:RU363019}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary):
Gene names (synonym):
Mass: 24,268
Subunit structure [CC]:
Gene ontology (GO): peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]
Gene ontology IDs: GO:0003755; GO:0006457
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the cyclophilin-type PPIase family. {ECO:0000256|RuleBase:RU363019}.; SIMILARITY: Contains 1 PPIase cyclophilin-type domain. {ECO:0000256|RuleBase:RU363019}.
Protein families: Cyclophilin-type PPIase family
Coiled coil:
Domain [FT]: DOMAIN 54 202 PPIase cyclophilin-type. {ECO:0000259|PROSITE:PS50072}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NG83
MEROPS:
EnsemblBacteria KO: ABX81363
UniPathway: K03768
CDD:
Gene3D:
HAMAP: 2.40.100.10
InterPro:
PANTHER: IPR029000;IPR024936;IPR020892;IPR002130
PIRSF: PTHR11071
PRINTS:
PROSITE: PR00153
Pfam: PS00170;PS50072
ProDom: PF00160
SMART:
SUPFAM:
TIGRFAMs: SSF50891

788449-789103(-)

>nucleotide sequence
TTACTTACTATAATATATTACAGGACTTGGTTCATAGTTCTTTAAATCCACTTCAATAGA
TTCAATCACTACCTTGGTTAAAGGTGCATCATTGGAATTCGTACTTAGACTCTCAATTTG
GTTTAAGATAGTAAAACCGCTTATAATACCACCAAAGGATGCATATGCGCCATCTAAATG
TGGTGAGGTGGATGTCATCATAAAAAACTGTGATGTTGCACTATTTTTATCACTAGTTCT
TGCCATGGAAAGCACACCATAAGTATGTTTTAGGTTGTTTAAAAACCCATTAGAAGTAAA
CTCACCACGAATTGGTAATTTTGAGTCCTTAACCATACCGCCTTGAACCATAAAATCTTT
GATAATTCTATGAAAACTGCTATCACTAAACTGATCATCTAATATATAGTCAATAAAATT
ATTGACGGTATTTGGTGCAACATCATGAAATAACTGTGCTGTAATAATGCCATAATCTTT
GACTTTAATAGTGATTATAGGGTTTTCATCATTTAAATAATTAAAGTACGCCAAATCCTC
TAATTTAACATCTACTTCTTCGCCTTTATCAGTTTCATCAGGTGTTTTACTTTCACATCC
TACAACTATAAAAACACTAAATAATACAAGAATTGATAATATTAATTTCCTCAT

>protein sequence
MRKLILSILVLFSVFIVVGCESKTPDETDKGEEVDVKLEDLAYFNYLNDENPIITIKVKD
YGIITAQLFHDVAPNTVNNFIDYILDDQFSDSSFHRIIKDFMVQGGMVKDSKLPIRGEFT
SNGFLNNLKHTYGVLSMARTSDKNSATSQFFMMTSTSPHLDGAYASFGGIISGFTILNQI
ESLSTNSNDAPLTKVVIESIEVDLKNYEPSPVIYYSK