ACL_RS03800

Uniprot: A9NGA1
Description: 2,5-diketo-D-gluconic acid reductase
EC number:
Annotation score: 1 out of 5
Miscellaneous [CC]:
Protein existence: Predicted
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site: ACT_SITE 53 53 Proton donor. {ECO:0000256|PIRSR:PIRSR000097-1}.
Binding site: BINDING 111 111 Substrate. {ECO:0000256|PIRSR:PIRSR000097-2}.
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site: SITE 78 78 Lowers pKa of active site Tyr. {ECO:0000256|PIRSR:PIRSR000097-3}.
Gene names (primary):
Gene names (synonym):
Mass: 30,804
Subunit structure [CC]:
Gene ontology (GO): oxidoreductase activity [GO:0016491]
Gene ontology IDs: GO:0016491
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities:
Protein families:
Coiled coil:
Domain [FT]: DOMAIN 18 268 Aldo_ket_red. {ECO:0000259|Pfam:PF00248}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NGA1
MEROPS:
EnsemblBacteria KO: ABX81381
UniPathway:
CDD:
Gene3D: cd06660
HAMAP: 3.20.20.100
InterPro:
PANTHER: IPR001395;IPR018170;IPR020471;IPR023210
PIRSF: PTHR11732
PRINTS: PIRSF000097
PROSITE: PR00069
Pfam: PS00798;PS00062
ProDom: PF00248
SMART:
SUPFAM:
TIGRFAMs: SSF51430

801647-802466(+)

>nucleotide sequence
ATGAAAGTTATTAATCAGCATTACACATTAAGCAATGGGGTCAAAATACCAAAAATTGGA
CTAGGTACTTGGCAGGTAAAAGATGGTGATGAGGCATATAATTCTGTCTTAATTGCCCTT
AAAAATGGCTATCGTCATATTGATACTGCAGAAGGCTATCGGAATGAAGCATCTGTTGGA
CGCGCCATTAAAGATTCAGGCATTCCTCGTGATGAAATATTTGTCACCTCTAAACTAGAA
TCACATATTAAAACGTATGAAGGTGCACTTGAAGCATTTGACAAGACACTAAAAGCCCTT
GATTTTGAATATTTAGATTTATTCTTAATTCATGCACCTTGGCCATGGGATGAAGTTGGT
AAAGAATGTCATGAAGGTAATGTATTAGCTTATAAAGCCATGGAAAAACTATATAAAGAT
GGAAAAATTAGAGCAATCGGAATATCTAATTTTGAACCAGTTGACATAGAAAATATCATT
ACTCATTGTGAAATTGTTCCACATGTGAATCAAATTGCTTACTTTATTGGACTAGATCAA
TCAAAAACTATTGAAAGTTGTAATAAGCATAATATATTTGTTGAAGCCTACTCTCCTTTA
GGTACAGGCCGTTTATTATCTAATGAAGTTATAGTTCAAATGGCAGAAAAATATCAAGTA
TCACCCGCACAAATCTGTATCCGTTACTGCTTACAAAAAGGCACTGCACCATTACCAAAA
TCAACACATGAAGAACGTATTATTATGAATACAAAAGTGGATTTTGAAATTAGTACTGAT
GATATGAATGTCTTAGATCACGTCAAGAAGAATTTCTAA

>protein sequence
MKVINQHYTLSNGVKIPKIGLGTWQVKDGDEAYNSVLIALKNGYRHIDTAEGYRNEASVG
RAIKDSGIPRDEIFVTSKLESHIKTYEGALEAFDKTLKALDFEYLDLFLIHAPWPWDEVG
KECHEGNVLAYKAMEKLYKDGKIRAIGISNFEPVDIENIITHCEIVPHVNQIAYFIGLDQ
SKTIESCNKHNIFVEAYSPLGTGRLLSNEVIVQMAEKYQVSPAQICIRYCLQKGTAPLPK
STHEERIIMNTKVDFEISTDDMNVLDHVKKNF