ACL_RS03915

Uniprot: A9NGC4
Description: aspartate kinase
EC number: 2.7.2.4
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: ATP + L-aspartate = ADP + 4-phospho-L-aspartate. {ECO:0000256|RuleBase:RU003448}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): lysC
Gene names (synonym):
Mass: 43,750
Subunit structure [CC]:
Gene ontology (GO): amino acid binding [GO:0016597]; aspartate kinase activity [GO:0004072]; lysine biosynthetic process via diaminopimelate [GO:0009089]
Gene ontology IDs: GO:0004072; GO:0009089; GO:0016597
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the aspartokinase family. {ECO:0000256|RuleBase:RU003448}.
Protein families: Aspartokinase family
Coiled coil:
Domain [FT]: DOMAIN 262 345 ACT. {ECO:0000259|PROSITE:PS51671}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NGC4
MEROPS:
EnsemblBacteria KO: ABX81404
UniPathway: K00928
CDD:
Gene3D:
HAMAP: 3.40.1160.10
InterPro:
PANTHER: IPR002912;IPR001048;IPR005260;IPR001341;IPR018042
PIRSF:
PRINTS: PIRSF000726
PROSITE:
Pfam: PS51671;PS00324
ProDom: PF00696
SMART:
SUPFAM:
TIGRFAMs: SSF53633

824609-825812(-)

>nucleotide sequence
CTAAACATTGAAGTGTTTAGCTAATACTTCAACGACTTTATTCTTATATTTATTATCAAA
TGTATAGGAAATAGATATTTCAGATGTTGTAACTAACTTCACTTCTAAATCATTTTCTGC
AAATAATTCAAATACTTCTGCAGCAATACCAGATTGGGAGCGCATCGCACTACCTACAAT
AGATACCTTTACAACTTCATTTACTTTTAATACTTGAATGGTTGGGTTTTTAGCTTCAAA
TTTATCAAGTACTTCGTTGACTGCATCTAAATCATCAGCATGGGCCGTAAATGCAATATT
AATGGTACCACCCACACTAGGGTTTTGGTTAATAACGTCAATATTAACTTCGTTTAGTGC
TAAATCTTTAAACAGTTCTGCAGTAATCTTAGTTGAATAAGGTATACGGCGAATTGAAAC
CATAACTACTTTTTCTGTAACAGCAATACCAGTAATTTTTTTATCTTCCATGTTTTGTTT
GTACTCCTTAATGTAAGTCCCTTCTAAAGGGTTTTTAAGTGATGTGACATAGACTGTTAC
ACCATAGTTTTGAGCAATATCAATGCTTCTAGGTTCCATGATATTCGCACCTAAAAATGC
CATTTCTTTCATTTCTTCATAATCTATTTGGGTTAATTTTTGAGCATCCGGATAAATCCT
AGGATCCACACCATAAATGCCTGAAACATCTGTATAAATTTCACAAATAGCACCAAGTTT
AGCTGCTAGAGCAATTGCTGTTGTATCTGATCCACCACGACCTAAAGTAGTGACTTCACC
TGCTTCATTAAAACCTTGAAAACCTGCGACAATGACAATATTACCTGCCTGAATATGCGC
TTCAACACGTCTTGTATCAATACTTGATATTTTATTTTTAGTATGAGTACCCTTGGTTAA
AATCCCTGCTTTTTCTCCAGTTAAAGCAATCGATTTATAACCCATATCATTTAACATAAT
AGAAAGTAACGCGATTGATACAACCTCACCAGTTGATATGAGTAAATCCACATCACGCTT
ATTTGGATATTTTGTAATATCTTTGGCCATTTTAATTAAACTATTTGTAGTTTTTCCCAT
GGCTGATAATACAACAACGAGTTCATTATAGGTGTTTTTCTTTTCAATAATCGTTTGGGC
AACTTCTTTCATTAAATCTAGGTTTTGAACACTAGAACCACCAAACTTTAAAACTGCTCT
CAT

>protein sequence
MRAVLKFGGSSVQNLDLMKEVAQTIIEKKNTYNELVVVLSAMGKTTNSLIKMAKDITKYP
NKRDVDLLISTGEVVSIALLSIMLNDMGYKSIALTGEKAGILTKGTHTKNKISSIDTRRV
EAHIQAGNIVIVAGFQGFNEAGEVTTLGRGGSDTTAIALAAKLGAICEIYTDVSGIYGVD
PRIYPDAQKLTQIDYEEMKEMAFLGANIMEPRSIDIAQNYGVTVYVTSLKNPLEGTYIKE
YKQNMEDKKITGIAVTEKVVMVSIRRIPYSTKITAELFKDLALNEVNIDVINQNPSVGGT
INIAFTAHADDLDAVNEVLDKFEAKNPTIQVLKVNEVVKVSIVGSAMRSQSGIAAEVFEL
FAENDLEVKLVTTSEISISYTFDNKYKNKVVEVLAKHFNV