ACL_RS03960

Uniprot: A9NGD3
Description: phosphomevalonate kinase
EC number: 2.7.4.2
Annotation score: 1 out of 5
Miscellaneous [CC]:
Protein existence: Predicted
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): mvaK2
Gene names (synonym):
Mass: 39,325
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphomevalonate kinase activity [GO:0004631]; phosphotransferase activity, alcohol group as acceptor [GO:0016773]
Gene ontology IDs: GO:0004631; GO:0005524; GO:0005737; GO:0016773
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities:
Protein families:
Coiled coil:
Domain [FT]: DOMAIN 107 165 GHMP_kinases_N. {ECO:0000259|Pfam:PF00288}.; DOMAIN 270 331 GHMP_kinases_C. {ECO:0000259|Pfam:PF08544}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NGD3
MEROPS:
EnsemblBacteria KO: ABX81413
UniPathway: K00938
CDD:
Gene3D:
HAMAP: 3.30.230.10;3.30.70.890
InterPro:
PANTHER: IPR013750;IPR006204;IPR006206;IPR005917;IPR020568;IPR014721
PIRSF:
PRINTS:
PROSITE: PR00959
Pfam:
ProDom: PF08544;PF00288
SMART:
SUPFAM:
TIGRFAMs: SSF54211;SSF55060

834887-835928(-)

>nucleotide sequence
TTACTCATCGTAATCCCATACCTTTATGTCAAGTGCAATTAATCCATTTTTAATCCATGC
ATCTTGAAGCGTTCTTTTATCTGTTTCATTTTTTGTAAGTGCTATACCACAGTCTCCATA
CCCTGCACCACTAGTTTTAGCTGAATAGCCATAATCACTAGCAATTTGAATCATCTTTTT
AAATGGTTCTGATTCAATAATAATACCTGCATTTTCTTCTAATTCATTCAGTTTTTGACG
GTATAAATCAATCATGTACTTTATTGTATAATAATCTGACCTTATAAACGCTTCTTTAAA
TTGATTGACAATGATTTTAGTTTTTGTTAAAAAGTTTGCATACCAATTACTCCCACTAAA
ATTTGTCATTTTATCAGTGTATGCTTTGGTAGATTGTGATACACCTGAAAAGCAGACAGC
CAACTTGATAGATCCTTTTCGTAGTTTTTCTATTTTAAGCAGTGGCCAAGTCATCTCCAT
GACTTCTGAAATATGACCTTTTCTATTTAATATCCAAATAAGATCATATCTTTGGTAAAA
TACCCAACCACCATAAATGGATGCAGCTAATTCTCCACCAGATGTAATATCAGAAATTTC
TATTTGAGCTAGTACACTTAATTTAAATAAGTCCAATTTTGAGATTTCAATACCATGGAA
ATTTAAAATACCCTTAATAACAGCGACTATAACGGCACCTGATGAACCTAAACCATATTT
AATGTTATCCTTGCTTGTAAGTTCGGAAAACAGTTGAATACTATAACTTTTAGGTGTGAT
ATGTTTATATTTCATATATTTATGAGCAATGTAAACAGCGGCTTTTGCATGTGTTAATGT
ATCATAAACAAAGACAGGCAATTGATCTGATAACATCCATCTAAAATGCCCCATTTCAGA
TGAAAATTGGTAATCAGAATCTTCTTTAACCCGAACGTGTATAAACTTATCAACAGCTAC
TATCACTGCTTCATTACCAGGTTTAATAACTGAATATTCCCCAATAATGAATAGTTTTCC
AGGTATTTTTAGTGATATCAT

>protein sequence
MISLKIPGKLFIIGEYSVIKPGNEAVIVAVDKFIHVRVKEDSDYQFSSEMGHFRWMLSDQ
LPVFVYDTLTHAKAAVYIAHKYMKYKHITPKSYSIQLFSELTSKDNIKYGLGSSGAVIVA
VIKGILNFHGIEISKLDLFKLSVLAQIEISDITSGGELAASIYGGWVFYQRYDLIWILNR
KGHISEVMEMTWPLLKIEKLRKGSIKLAVCFSGVSQSTKAYTDKMTNFSGSNWYANFLTK
TKIIVNQFKEAFIRSDYYTIKYMIDLYRQKLNELEENAGIIIESEPFKKMIQIASDYGYS
AKTSGAGYGDCGIALTKNETDKRTLQDAWIKNGLIALDIKVWDYDE