ACL_RS03965

Uniprot: A9NGD4
Description: diphosphomevalonate decarboxylase
EC number: 4.1.1.33
Annotation score: 1 out of 5
Miscellaneous [CC]:
Protein existence: Predicted
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): mvaD
Gene names (synonym):
Mass: 35,172
Subunit structure [CC]:
Gene ontology (GO): cytosol [GO:0005829]; ATP binding [GO:0005524]; diphosphomevalonate decarboxylase activity [GO:0004163]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]
Gene ontology IDs: GO:0004163; GO:0005524; GO:0005829; GO:0019287
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities:
Protein families:
Coiled coil:
Domain [FT]: DOMAIN 90 147 GHMP_kinases_N. {ECO:0000259|Pfam:PF00288}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NGD4
MEROPS:
EnsemblBacteria KO: ABX81414
UniPathway: K01597
CDD:
Gene3D:
HAMAP: 3.30.230.10;3.30.70.890
InterPro:
PANTHER: IPR013750;IPR006204;IPR005935;IPR029765;IPR020568;IPR014721
PIRSF: PTHR10977
PRINTS: PIRSF015950
PROSITE:
Pfam:
ProDom: PF00288
SMART:
SUPFAM:
TIGRFAMs: SSF54211;SSF55060

835924-836872(-)

>nucleotide sequence
TCATAAGGAACTTACCCCCATTCCTGTATAACTTACTATAACCTTAGATAATTTTTCATA
TCTAGCTTTTATGGTTTCTACATACTCTTTTTTTGTTAAAATTTTTACATTTGCACCTGC
ATCCATTGTGTAGTATACAGGTATACCTTCATTACGTATTTTTTCAGTTAAATCCATGAC
TTTAAATGATTGATCTGTTAGATAAGAAACACCAGTTTCTTGGATAATATAATGCATTAA
ACTTGCGTGAGATTCTGCAATAGACCCCATCTTGTCAAAATCATTTTCTATTATGGCTTC
TTTCATATCATTTAATGCATCTTGTGTGCTTAATATCCATAACTCTTTTAAGTCTGGATA
TTCGTTTAATCTGTTCATTGCATCGGTACTATTAACTTTTTTAGGAGTTTCATCAATTAA
GCATACAATTACTGCTAAATCATCCATGTGAGTTAAATGTTCTGCATAAGAAGACATATG
ATCATGGCCTTCATGCCATAAAACTAGACCACCATAGATAGAACGTGATGCAGAGCCACT
GCCTAATCTTGCGAGTGATGAAAGTTCTTTAGAATCTAAATTTAGTCCATATGCTTTAGT
TGCAGCATATGCAAGTGCTGCAAATGCTGATGAAGAGGATGCTAATCCTGCTTTTTTAGG
TACAAAGTTATAAGAGGTTATCTTTGCATAAAAAGGAATACTATATAACTTTCTTAATTT
ATCCATATATTTAGTGACTCTTAAATACTCTCCACCAGTTATGATTTCATCATCTATGAG
TAAAATATCCGCTGTAAGTGTTGGATCATATGTAACTGTGGTTTTTGTATAAAAGGCATC
TAAAGTTAGACTTATAGAGGATGTTAGTGGTAAATTCCATTCTATGTCCTTTTTTCCCCA
GTATTTAATAAGTGCTATATTTACGTTTGCTATTGCTGTGTGTGTCAT

>protein sequence
MTHTAIANVNIALIKYWGKKDIEWNLPLTSSISLTLDAFYTKTTVTYDPTLTADILLIDD
EIITGGEYLRVTKYMDKLRKLYSIPFYAKITSYNFVPKKAGLASSSSAFAALAYAATKAY
GLNLDSKELSSLARLGSGSASRSIYGGLVLWHEGHDHMSSYAEHLTHMDDLAVIVCLIDE
TPKKVNSTDAMNRLNEYPDLKELWILSTQDALNDMKEAIIENDFDKMGSIAESHASLMHY
IIQETGVSYLTDQSFKVMDLTEKIRNEGIPVYYTMDAGANVKILTKKEYVETIKARYEKL
SKVIVSYTGMGVSSLW