ACL_RS03970

Uniprot: A9NGD5
Description: mevalonate kinase
EC number: 2.7.1.36
Annotation score: 1 out of 5
Miscellaneous [CC]:
Protein existence: Predicted
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): mvaK1
Gene names (synonym):
Mass: 34,329
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; ATP binding [GO:0005524]; mevalonate kinase activity [GO:0004496]; isoprenoid biosynthetic process [GO:0008299]
Gene ontology IDs: GO:0004496; GO:0005524; GO:0005737; GO:0008299
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities:
Protein families:
Coiled coil:
Domain [FT]: DOMAIN 88 154 GHMP_kinases_N. {ECO:0000259|Pfam:PF00288}.; DOMAIN 222 299 GHMP_kinases_C. {ECO:0000259|Pfam:PF08544}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NGD5
MEROPS:
EnsemblBacteria KO: ABX81415
UniPathway: K00869
CDD:
Gene3D:
HAMAP: 3.30.230.10;3.30.70.890
InterPro:
PANTHER: IPR013750;IPR006204;IPR006205;IPR006206;IPR020568;IPR014721
PIRSF: PTHR10457
PRINTS:
PROSITE: PR00959
Pfam:
ProDom: PF08544;PF00288
SMART:
SUPFAM:
TIGRFAMs: SSF54211;SSF55060

836868-837810(-)

>nucleotide sequence
TCATAATACGATTTCCTTTAAGTCATAAAGCCAAGTGTTTACTGCCCCTGCATTCTTTAG
TGCATCTGCAATACGTATACCTTGATCTTCATTTTGTGCGAGTGCAATCATGCAACCACC
CTTACCACCACCGGTAAGTTTAGCACCTAAAGCACCGTTTAATAGTGATACTTCTACTAA
TTTTTCAAGTAAGTCATCTGATACTTTAATACTTCTAAGCAACTGATGAGCCTCAGTCAT
AGCAAGACCAAGTCGAATAATTTCATTAGTCTCTAAATATGTTCTAACTTCATTTGTAAG
TTCTTCTAATCTATCCATAATTGGAGATACAATCGTTGGGTTATCCGTCCATAGTTGTTT
TACTTCTTGTACTGCTTCTTTAGTTAAACCTTTTTTACCGGTATCAGCAACTACTATAAC
TGCATCCATTTTTAGTGGAATTAACGTCTTACCTAAATCCTTTTGATAAAATACAGCTTG
TCCAAATGCAATCGTAATCGCGTCTAATCCAGATGGATTAACGTGATGTATTTGTTCGGC
TACATCGACAAAATAATTTAGACGTTCTTGGCTTAATTCTACTTTGAAAGCATCAAAAAG
CGATCTAACAATCGCTATCGAAACAGATGCGGATGAACCTAAACCACGTTGTGGTGGTAA
TGAGGATTCAATTTGAATATGTATACCATGAAATGGTTGTTTTAAATATACTAAGACAAT
ATATATAAGTTGTTTTATACCGTAAAGTGTGTCCGGAGCATCATCTAAATAACCTTTATG
ATAAAAAGAATCGATTGTAATTTTATCATTTGTTTTAAAGACTTTTGAGCTAATTTGTGC
TTGTTTAAAGGGTAGTGCAATTGCGGGTTTTCCATAAACTACTGAGTGTTCACCCATTAA
TATGATCTTTCCGCTTGCGACACCATGTCCAAAATCTATCAT

>protein sequence
MIDFGHGVASGKIILMGEHSVVYGKPAIALPFKQAQISSKVFKTNDKITIDSFYHKGYLD
DAPDTLYGIKQLIYIVLVYLKQPFHGIHIQIESSLPPQRGLGSSASVSIAIVRSLFDAFK
VELSQERLNYFVDVAEQIHHVNPSGLDAITIAFGQAVFYQKDLGKTLIPLKMDAVIVVAD
TGKKGLTKEAVQEVKQLWTDNPTIVSPIMDRLEELTNEVRTYLETNEIIRLGLAMTEAHQ
LLRSIKVSDDLLEKLVEVSLLNGALGAKLTGGGKGGCMIALAQNEDQGIRIADALKNAGA
VNTWLYDLKEIVLW