ACL_RS04070

Uniprot: A9NGF7
Description: aspartate--tRNA ligase
EC number: 6.1.1.12
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): aspS
Gene names (synonym):
Mass: 65,275
Subunit structure [CC]: SUBUNIT: Homodimer. {ECO:0000256|SAAS:SAAS00385220}.
Gene ontology (GO): cytoplasm [GO:0005737]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; tRNA aminoacylation for protein translation [GO:0006418]
Gene ontology IDs: GO:0003676; GO:0004815; GO:0005524; GO:0005737; GO:0006418
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family. {ECO:0000256|SAAS:SAAS00571505}.
Protein families: Class-II aminoacyl-tRNA synthetase family
Coiled coil:
Domain [FT]: DOMAIN 142 537 AA_TRNA_LIGASE_II. {ECO:0000259|PROSITE:PS50862}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NGF7
MEROPS:
EnsemblBacteria KO: ABX81437
UniPathway: K01876
CDD:
Gene3D:
HAMAP: 2.40.50.140;3.30.1360.30
InterPro:
PANTHER: IPR004364;IPR018150;IPR006195;IPR004524;IPR002312;IPR004115;IPR029351;IPR012340;IPR004365
PIRSF: PTHR22594;PTHR22594:SF5
PRINTS:
PROSITE: PR01042
Pfam: PS50862
ProDom: PF02938;PF00152;PF01336
SMART:
SUPFAM:
TIGRFAMs: SSF50249;SSF55261

856109-857816(-)

>nucleotide sequence
TCATTTAATCACCTTCAAACCTAAGTCTTCTAATTGAAGTTTATCAATTGGACTTGGAGA
TTCCATCATAATATCTCTTGCAGATTGTGTCTTAGGAAACGCAATAACGTCTCTAATATT
ATCTGTCTTAGTTGCAAGCATTACAATTCTATCTAATCCAAATGCAATACCACCATGTGG
CGGTGTTCCATATTTTAATGCATCAATGAAAAATCCAAATTTATTTCTGATTTCTTCTTG
CGTAAATCCTAATTTTTCAAACATTTCATTTTGAACTTCTTGGTTATAAATACGCATGGA
TCCACCACCAACTTCATAACCATTCCATACAAGGTCATAAGCTTTAGCTAATGTATCTTT
TGGATTGTTTCTGAAATCTTCTAAATCTTTAGGTGCTGTAAACGGATGGTGTCTAGCATA
TAATCTTTGATCTTCTTCACTATATTCAAATAGCGGGAAGTCAACAATCCATACTAAACT
TTCTAAAGTTTCATCGATATAACCTAAATCTTTAGCTAATTCTTTTCTTAAGGCACCACA
TGCATTGGTTGCACCTTCATAAGTACCTGGCACAATAAATAATGTGTAACCATCAGCAAC
TACATTTTCATCAAAGAATTTAGACACTGAACCACTTAATTGACCACCTTCATGTTTCAC
ATATGCTAGTGTATCTCCATGGTTTTTCTTAACAATTTCTGTTAATTTATCGAAGTATTT
ACGTGTAAATAATGCATTATTTGGTAAGGTAAAGCCTCTTAAAGACGCTTTAGACTCAAA
TAATGGTACATGATAAGTGCTTAGTTTATCAGTTAAGTCTTCAATTTTTAATTCATATCT
TAAGTCTGGTTTATCAGATCCGTACATATCAAAAGCATCTTGATATGTTAGTCGTGCTAT
TGGCAGTTTTAGTTCTTTACCTAAGATGTCTTTAAACATATTTGACATCATTTCTTCACC
AAGCTTCATAATATCTTCTTGAGTAATAAATGATGCTTCAATGTCAATTTGAGTAAACTC
TAATTGACGGTCAGCTCTTAAGTCTTCATCTCTAAAACATCTAGCAAATTGGAAGTATTT
TTCAAAGCCAGATACCATATATAATTGTTTAAACATTTGAGGAGATTGTGCAAGTGCATA
ACCTTCACCATGATAAAGTCTTGAAGGTACAATAAACTCCTTAGCACCTTCTGGTGTTGT
TTTCACTAAGTATGGTGTTTCTAATTCTAAAAAGTTATTATTAAGTAAAGAATTTCTAAT
ACTTTGAGTGATTTTACTTCTTTGTAATAAATAGTTTTTAGATGTTGGTTTTCTTAAATC
TAAATAGCGATATTTTAATCGAACTTCTTCAGAGATATTATCTTGTTCTGAAATAGTAAT
CGGTGTTGTCATTGCTGTATTTAAAATATTGAGTTCAGTAACGTCAATTTCAATATCACC
TGTTGTCATGAATTTATTTTTAGATTCACGTTCAATAACAATACCTTTAACTTCAACGAC
ATATTCTGATCTTACTTGACTTGCACGCTCATAGAGTGCAGTATTTGGTCTTACAACTAA
TTGAGTAATACCATATTGGTCTCTTAGGTCCATAAAGATAAGTCCGCCTAAGTTTCTAAC
CTTAGAAACCCATCCTTTTAAAAAGACGGTTTCATTTAAATTTTTAATTGTTAATTCATT
ATTATGATGGCTATATGTACTCATAAT

>protein sequence
IMSTYSHHNNELTIKNLNETVFLKGWVSKVRNLGGLIFMDLRDQYGITQLVVRPNTALYE
RASQVRSEYVVEVKGIVIERESKNKFMTTGDIEIDVTELNILNTAMTTPITISEQDNISE
EVRLKYRYLDLRKPTSKNYLLQRSKITQSIRNSLLNNNFLELETPYLVKTTPEGAKEFIV
PSRLYHGEGYALAQSPQMFKQLYMVSGFEKYFQFARCFRDEDLRADRQLEFTQIDIEASF
ITQEDIMKLGEEMMSNMFKDILGKELKLPIARLTYQDAFDMYGSDKPDLRYELKIEDLTD
KLSTYHVPLFESKASLRGFTLPNNALFTRKYFDKLTEIVKKNHGDTLAYVKHEGGQLSGS
VSKFFDENVVADGYTLFIVPGTYEGATNACGALRKELAKDLGYIDETLESLVWIVDFPLF
EYSEEDQRLYARHHPFTAPKDLEDFRNNPKDTLAKAYDLVWNGYEVGGGSMRIYNQEVQN
EMFEKLGFTQEEIRNKFGFFIDALKYGTPPHGGIAFGLDRIVMLATKTDNIRDVIAFPKT
QSARDIMMESPSPIDKLQLEDLGLKVIKW