ACL_RS04170

Uniprot: A9NGH7
Description: translation initiation factor IF-3
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. {ECO:0000256|HAMAP-Rule:MF_00080}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): infC
Gene names (synonym):
Mass: 20,624
Subunit structure [CC]: SUBUNIT: Monomer. {ECO:0000256|HAMAP-Rule:MF_00080}.
Gene ontology (GO): cytoplasm [GO:0005737]; translation initiation factor activity [GO:0003743]
Gene ontology IDs: GO:0003743; GO:0005737
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the IF-3 family. {ECO:0000256|HAMAP-Rule:MF_00080, ECO:0000256|SAAS:SAAS00544369}.
Protein families: IF-3 family
Coiled coil:
Domain [FT]: DOMAIN 12 81 IF3_N. {ECO:0000259|Pfam:PF05198}.; DOMAIN 89 172 IF3_C. {ECO:0000259|Pfam:PF00707}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NGH7
MEROPS:
EnsemblBacteria KO: ABX81457
UniPathway: K02520
CDD:
Gene3D:
HAMAP: 3.10.20.80;3.30.110.10
InterPro: MF_00080
PANTHER: IPR001288;IPR019815;IPR019814
PIRSF: PTHR10938
PRINTS:
PROSITE:
Pfam:
ProDom: PF00707;PF05198
SMART:
SUPFAM:
TIGRFAMs: SSF54364;SSF55200

875586-876126(-)

>nucleotide sequence
TTATCCTCTTTCATCTTTCTTTGCAGGTGCAATAATTGCTATAATCTGCATACCTTCTAG
TTTAGGTTGTGATTCTACAACAACACCTTGTAGTAATTCAACAAATTTGTTAACTTGCTC
GAATCCGATGTCCTTGTGAGTAATCATACGTCCTCTAAAACGTAATGATACTTTTAATTT
GTCACCACCATTAATAAACTTTTGAGCATTTCTTAATTTGGTGTCAAAGTCATGTTTATC
AATTGTAGGTGATAACTTGATTTCTTTTAGCTTAACGATTTGTTGATTTTTCTTCATTTC
TTTAAGCTTCTTTTGTTGGTCATAACGATGTTTTGAATAATCTAATAGTTTTGCAACCAT
TGGCTTTGCATTTTCAGGTGATACAACTAAAATGTCGATATCTCTTTCTCTTGCAATCTC
TAATGCTTGTCTACGATCAAACGTTCCAAGTCTTTGACCTTCTTCATCAATAATTAAGAA
TTGTCCGTTTGGCAATGTCTCATTTACTAAGTCTGAGTTTTGTTTGGGTTTGAAGCCCAT

>protein sequence
MGFKPKQNSDLVNETLPNGQFLIIDEEGQRLGTFDRRQALEIARERDIDILVVSPENAKP
MVAKLLDYSKHRYDQQKKLKEMKKNQQIVKLKEIKLSPTIDKHDFDTKLRNAQKFINGGD
KLKVSLRFRGRMITHKDIGFEQVNKFVELLQGVVVESQPKLEGMQIIAIIAPAKKDERG