ACL_RS04340

Uniprot: A9NGL1
Description: elongation factor P
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. {ECO:0000255|HAMAP-Rule:MF_00141}.
Pathway: PATHWAY: Protein biosynthesis; polypeptide chain elongation. {ECO:0000255|HAMAP-Rule:MF_00141}.
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): efp
Gene names (synonym):
Mass: 20,998
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; translation elongation factor activity [GO:0003746]
Gene ontology IDs: GO:0003746; GO:0005737
Chain: CHAIN 1 185 Elongation factor P. /FTId=PRO_1000076501.
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the elongation factor P family. {ECO:0000255|HAMAP-Rule:MF_00141}.
Protein families: Elongation factor P family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NGL1
MEROPS:
EnsemblBacteria KO: ABX81491
UniPathway: K02356
CDD:
Gene3D:
HAMAP: 2.30.30.30;2.40.50.140
InterPro: MF_00141
PANTHER: IPR015365;IPR012340;IPR014722;IPR020599;IPR013185;IPR001059;IPR013852;IPR011768;IPR008991
PIRSF:
PRINTS: PIRSF005901
PROSITE:
Pfam: PS01275
ProDom: PF01132;PF08207;PF09285
SMART:
SUPFAM: SM01185;SM00841
TIGRFAMs: SSF50104;SSF50249

908065-908623(-)

>nucleotide sequence
TTACGCTCTTGAAACGTAAGTACCTTCAGTTGTATTCACGATGATCTTTTCACCAGTTTC
AATGAACATTGGTACTTTAACTAAGTATCCAGACGCCAAATAAGCATCTTTCATTGCGTT
AGTTTTTGTATCACCTTTAACACCAGGTACAGTTTCTTTAACTTCTAATACTAATTTTTC
AGGTAAGTTTACACCAATAATTTCTGTTCCGTAAAAGTTGATTTCAACTTCTAAACTTTC
ATATAAGAAATTAAGTTCGTATTCGATTTGAGATTTGTCCACTTCGATTTGTTCATAAGT
TTCCATATTCATGAATACGTGTGTGTCACCTGATGCATATAAGTATTGCATTTTAATGCG
GTCGATAATCGCACGTTCAACTTTATCGCCAGATTTGAAAGTTATTTCTTGAATGTTTTT
TGTACGTAAATTACGTAATCTTGTATTAATTAGCGCTCCACTTCTAGCTGTTTTAGAATG
TAGGAAGTCTAATATTACATAGATTTGGCCGTCAACTTCGATTGTTAAGCCTGTTTTAAA
ATCACTTGTAGATACCAT

>protein sequence
MVSTSDFKTGLTIEVDGQIYVILDFLHSKTARSGALINTRLRNLRTKNIQEITFKSGDKV
ERAIIDRIKMQYLYASGDTHVFMNMETYEQIEVDKSQIEYELNFLYESLEVEINFYGTEI
IGVNLPEKLVLEVKETVPGVKGDTKTNAMKDAYLASGYLVKVPMFIETGEKIIVNTTEGT
YVSRA