ACL_RS04360
| Uniprot: A9NGL5
Description: hypothetical protein EC number: Annotation score: 2 out of 5 Miscellaneous [CC]: Protein existence: Inferred from homology Catalytic activity: Cofactor: Enzyme regulation: Function [CC]: FUNCTION: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. {ECO:0000256|HAMAP-Rule:MF_00149, ECO:0000256|SAAS:SAAS00315683}. Pathway: Active site: Binding site: Calcium binding: DNA binding: Metal binding: Nucleotide binding: Site: Gene names (primary): mutL Gene names (synonym): Mass: 65,031 Subunit structure [CC]: Gene ontology (GO): ATP binding [GO:0005524]; mismatched DNA binding [GO:0030983]; mismatch repair [GO:0006298] Gene ontology IDs: GO:0005524; GO:0006298; GO:0030983 Chain: Signal peptide: Domain [CC]: Sequence similarities: SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family. {ECO:0000256|HAMAP-Rule:MF_00149, ECO:0000256|SAAS:SAAS00554811}. Protein families: DNA mismatch repair MutL/HexB family Coiled coil: Domain [FT]: DOMAIN 209 327 DNA_mis_repair. {ECO:0000259|SMART:SM01340}.; DOMAIN 389 526 MutL_C. {ECO:0000259|SMART:SM00853}. Motif: Region: EMBL: CP000896 ProteinModelPortal: A9NGL5 MEROPS: EnsemblBacteria KO: ABX81495 UniPathway: K03572 CDD: Gene3D: HAMAP: 3.30.230.10;3.30.565.10 InterPro: MF_00149 PANTHER: IPR013507;IPR014762;IPR002099;IPR020667;IPR003594;IPR014790;IPR020568;IPR014721 PIRSF: PRINTS: PROSITE: Pfam: PS00058 ProDom: PF01119;PF08676 SMART: SUPFAM: SM01340;SM00853 TIGRFAMs: SSF54211;SSF55874 |
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910416-912126(-) >nucleotide sequence ACGTCCATGTGGGCAGGTATACGGATTTTTACACTGTCTTAAATCATTTTCTATTTTTTT TATTTCTTGTAGGGATAGTTGTCGGTTTGCTTTAATTGCACCTTTACATGCAATATCTTT AGCTAGTTGGTTTCTTAAGATCTTTAGATCAATTTTGCCATTATCTTGAAGCTGATCTAC TAAAGCATGCACTGCTTTATCAAGTTCATTTTCACGTAACCATGTAGGATGTTTTACAAC ACTAGCATTCTCAAATTCAAAGCCAATATGTTTTAATAAATGACGATGTGTATGTAAAAT TAATGCATCTTGTTCAGTGATATGTAGATCTTTAGCAACTAAGAGTTCATAGTAATCACT CTTTAAGGCACCAACTTTATCTTCATAATATTCATAGCGAATACGTTCTGCAGCAGCATG TTGATCCATTAGGAAGAGTCCTTCATCATTTTGATACAGTAAGTAAGTACCTGAAAGTGT TCCAATATACTCTAAATGTGGTAGTTTTTCAGTTTCTACAATCAGTGATTCAACTACTGG TGCCTCATTAAGTTCAAATAACTGTTCTGGTAAATCTTCTTGTTTAACAAAATCAAAGAT GTCAATAATGGTTGGTTTAAATAAGTCTTTTCTAACTTCGGTAATTGCTTGCCTAATTGG CATATTACCAGATTCTAAGGTTTTTCTTATCTCTGGTGCTAGTTGATATGCAAACATACG CTCGTTAGCAAGTTTAGCCTCCATCTTTTGAGGATGGACATTCACATCCACTAAACTTGG ATCTAGCGTAATATATAGTAAGCACAATGGATATTTGTTTGTCATTAAAAATGTTTGATA ACCATCAATAATACTTTGACTAATGACATAGTTTTTAATATATCTTTGATTAATAAAGAT GTTGATGTCACTTCGTTTAGAACGAACAAATTTAGGATCTACTAAATAGGCATCTACTTT AATTTTACCTAGATATGTAGATAATACTTTCATACCTTCAGTTATCTTTTTACCATAGAT TGCTTCTATGAGTTGATTCATTTGGTTATTGCCCAATGTAGATTTTACTAATTTATTATC CATATAAAGTTTAAAACTAATCGTTGGATGTGAAAGTGCTAGTTTGTCAACTATTTCAGT GATTGCATTTTTTTCTGCGTATTCAGATTTCATGTACTTAAAGCGTGCCGGCGTATTATA AAAGAGTTCTTTAACAATAATTTTAGTGCCCTTATTTAATACTGCAACACCTTCATCAAC AACCTTAGAATTTTCTAACTTTAAAAAGTATCCGTCGCCAGCATCTGTTCTAGACATAAT CTCAATTTTAGATACAGATAAAATAGAAGGGAGTGCCTCACCTCTAAAACCTAGGGATCT GATATCATTTAAATCTGATATTTTAAATATCTTTGATGTAGCATGTCTAAGAAAAGCTTT ATGAAGGTTTTCTCTAGTCATACCACTTCCATCATCGGTAACGCTGATGGATTCAAGTCC CATATTATGAACTTCTATACTTATGTTTTTGGCTTCTGCATCAATTGCATTTTCAACTAA TTCTTTGATGACTGATGCAGGACGTTCAACGACTTCACCAGCTGCAATTGTATTGGCAAG CGCCATATCCATAATGGCTATATTTTTCAT >protein sequence GSGMTRENLHKAFLRHATSKIFKISDLNDIRSLGFRGEALPSILSVSKIEIMSRTDAGDG YFLKLENSKVVDEGVAVLNKGTKIIVKELFYNTPARFKYMKSEYAEKNAITEIVDKLALS HPTISFKLYMDNKLVKSTLGNNQMNQLIEAIYGKKITEGMKVLSTYLGKIKVDAYLVDPK FVRSKRSDINIFINQRYIKNYVISQSIIDGYQTFLMTNKYPLCLLYITLDPSLVDVNVHP QKMEAKLANERMFAYQLAPEIRKTLESGNMPIRQAITEVRKDLFKPTIIDIFDFVKQEDL PEQLFELNEAPVVESLIVETEKLPHLEYIGTLSGTYLLYQNDEGLFLMDQHAAAERIRYE YYEDKVGALKSDYYELLVAKDLHITEQDALILHTHRHLLKHIGFEFENASVVKHPTWLRE NELDKAVHALVDQLQDNGKIDLKILRNQLAKDIACKGAIKANRQLSLQEIKKIENDLRQC KNPYTCPHGRPVLIKLSNQDIEKMFKRIVW |
© Fisunov Lab of Proteomics, 2016.