ACL_RS04365

Uniprot: A9NGL6
Description: DNA mismatch repair protein MutS
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. {ECO:0000255|HAMAP-Rule:MF_00096}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding: NP_BIND 596 603 ATP. {ECO:0000255|HAMAP-Rule:MF_00096}.
Site:
Gene names (primary): mutS
Gene names (synonym):
Mass: 96,294
Subunit structure [CC]:
Gene ontology (GO): ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; mismatched DNA binding [GO:0030983]; mismatch repair [GO:0006298]
Gene ontology IDs: GO:0003684; GO:0005524; GO:0006298; GO:0030983
Chain: CHAIN 1 841 DNA mismatch repair protein MutS. /FTId=PRO_1000075550.
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the DNA mismatch repair MutS family. {ECO:0000255|HAMAP-Rule:MF_00096}.
Protein families: DNA mismatch repair MutS family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: ABX81496
UniPathway: K03555
CDD:
Gene3D:
HAMAP: 3.30.420.110;3.40.1170.10;3.40.50.300
InterPro: MF_00096
PANTHER: IPR005748;IPR007695;IPR000432;IPR007861;IPR007696;IPR016151;IPR007860;IPR027417
PIRSF:
PRINTS:
PROSITE:
Pfam: PS00486
ProDom: PF01624;PF05192;PF05190;PF00488
SMART:
SUPFAM: SM00534;SM00533
TIGRFAMs: SSF48334;SSF52540;SSF53150;SSF55271

912136-914662(-)

>nucleotide sequence
TTATTTTTTTTCTTTACTTAAACTTTGTAGATATTTTAATTTAATCAAAGCATCAAGCGG
TGTCATTTGATTAATATCCAAGTCATTGATGTGATTTAATAAATCCTGAATATCATGCGG
AATGATTTGTCCAAGTTCTACTTTTTCTTCAAACATAAATAGATTATGATCAATGCCTTT
TCCATCTTTTTCTAATTTTTTAAGTAAGTATTTAGCACGTTTAATCACCGGATCCGGTAG
ATGTGCTAGGGCTGCTACTTGAATACCATAGGATTTATCTGATGAACCAAGTTCAACTTG
GTGTAGGAATACCATATGGTCTTTTTGTTCGATAGCTTTAACGTGTAAGTTAGTTATAAG
ATCATGTTTTTCTGATAATTTAGTCAGTTCATGATAGTGTGTTGAAAACATCATTTGAGC
TTTGATTTGGGTATGTACATACTCAATCATCGCCTGAGCAAGTGCAAGTCCATCATAGGT
TGCAGTACCTCGTCCTATTTCATCAAATAAAATAAGAGAGTTTTCTGTTGCATAAGTGAG
TGCATCATTTGCCTCAACCATCTCAACCATAAATGTAGACTTACCACCTGAGATATCATC
ACTTGAACCAATACGTGTAAATATTGCATCATATATTGGTAAATTTGCAGATGTAGCGGG
TACAAACATACCAGTTTGAGCCATAACAGTAATGACTGCAAACATACGCATATAAGTCGA
TTTACCACTCATGTTTGGTCCAGTTAAAATAAATATTTCACTTGGTTTCATGTGAATATG
GTTTTTAATGAACTCAACATGTTGTTCCACAACTGGGTGACGTCCATTTTCTATATCTAC
AATGCGGTTATGATTGAGTTTTGGTCTAACATATTTATACATTTCTGCTACTTTTGATAA
ACTGATATATTTATCAACTGATGCAATAATTTGACTTAATAATTGAAGTTCATGTGTATA
CGTTTTAGCAGTTTCTTTAATTTGATTAAATATTTCATACTCTAGTTTATCTGCTCTATC
TTTAGAGGATAAAATCTTATTTTCTGCATTCTTTAAATCTTCTGTAATATAACGTTCTGC
ATTAGCTAGTGTTTGTTTTCTAATATAACCAAATTCCTCTTGAATGAGTGGAATATTTCC
TTTAGATACTTCAATAAAATATCCAAATACACGGTTATAACCTACCTTTAAGTTCTTAAT
TCCGGTACGTTCTTTTTCCTCATTTTCAAACTTTTCTAACCATAAGTCACCGTTTTTAGC
AATACTTCTAAATTCATCTAAAGTTTCATCATATCCATCTTTGATGATGCCACCTTCTTT
AACAGTTAGGGGTGGTTCATTTTCAATCGATGCATCAAGTAATTGAAATAAAGTTTCAAA
AACATCTACCTTATCATTCATTTCATCAATAAGTGGATTATCAAATGAATCTAAAACTTC
TTTAAACTCTGGAATAAGACTAAGTGTTGTTTTAAGTTGAACTAAATCTCTAGCGTGTGT
TTGGTTACTTGAAACACGTCCTACTAATCTATTTAAGTCATAAACTTGTTCTAGTATAGA
TTCAAGTTTATTTCTTGGTTCAAATTGTGTAAAAGCTTCAATATAATCATATCTTTTTTC
TAGTAATTCTTTATCCTTTAAAGGATGTGTTAATTCATATCTTAGTAATCTAGAACCCAT
TGCAGTGGAAGTTTTATCAATCCACTGAATCAAGGTAGAATTGATATTTCCTGTTAAGGA
TTCTGTTAACTCTAAGTGATTTAAGACCTGGTGATCAAGTCTCATATATTGATCAACAAT
GACACTTTCAAAAGGCATTAAGTGAGATAAATCAAGTTTAGATTCTTTTTCTAAGTAATT
AATTAATAAAGAACCAGCTTCTTTGAGATGCTTTTCTTTTAAATTTCTTACAATTCTAGT
ATTTTGAACTTCTTGATTCGTATAAATGGATACTAAAATACTTTCTTGTTTAAAAAAGTT
TAATAAATAAATGTCCGAAGTGTTTGTTAAAACGATTTCTTTGAGTTTTAAATTAGATAC
TTCATCAGTTAAAGCTTGTTTGGTTAGACCATTTAAGATAAATGTATCACCCGTTGAAAT
ATCTGCATAACTTAATATATATCCATATTCTGATAAAGATACTGAACCGATAAAGTTATA
TTCATTTTTGGGTAGAATATCATCATCAATAATCATACCAGGAGTAATGAGTTGAACAAC
TTCACGTTCAACTAAACCCTTACCGGGTTCTGATGTTTGTTCAACAATTGCGATTTTAAA
GCCTTTAGTAATTAGTTTTTGAATGTATACTTTCGCTGCATGATGCGGTACACCACACAT
TGGAACAGTTTGACCTGCTTCCTTTTTAGTAAGCGTTATTTCTAGAACCTTGGATGCAGT
AATCGCGTCATCAAAAAACATTTCATAGAAATCACCAAGTCTAAAAAAGACTATCGCATC
TGCGTAGTCTTCTTTAATTTTTAAGTATTGTTGCATCATAGGTGTGTATTTAGAAATATC
TGACAT

>protein sequence
MSDISKYTPMMQQYLKIKEDYADAIVFFRLGDFYEMFFDDAITASKVLEITLTKKEAGQT
VPMCGVPHHAAKVYIQKLITKGFKIAIVEQTSEPGKGLVEREVVQLITPGMIIDDDILPK
NEYNFIGSVSLSEYGYILSYADISTGDTFILNGLTKQALTDEVSNLKLKEIVLTNTSDIY
LLNFFKQESILVSIYTNQEVQNTRIVRNLKEKHLKEAGSLLINYLEKESKLDLSHLMPFE
SVIVDQYMRLDHQVLNHLELTESLTGNINSTLIQWIDKTSTAMGSRLLRYELTHPLKDKE
LLEKRYDYIEAFTQFEPRNKLESILEQVYDLNRLVGRVSSNQTHARDLVQLKTTLSLIPE
FKEVLDSFDNPLIDEMNDKVDVFETLFQLLDASIENEPPLTVKEGGIIKDGYDETLDEFR
SIAKNGDLWLEKFENEEKERTGIKNLKVGYNRVFGYFIEVSKGNIPLIQEEFGYIRKQTL
ANAERYITEDLKNAENKILSSKDRADKLEYEIFNQIKETAKTYTHELQLLSQIIASVDKY
ISLSKVAEMYKYVRPKLNHNRIVDIENGRHPVVEQHVEFIKNHIHMKPSEIFILTGPNMS
GKSTYMRMFAVITVMAQTGMFVPATSANLPIYDAIFTRIGSSDDISGGKSTFMVEMVEAN
DALTYATENSLILFDEIGRGTATYDGLALAQAMIEYVHTQIKAQMMFSTHYHELTKLSEK
HDLITNLHVKAIEQKDHMVFLHQVELGSSDKSYGIQVAALAHLPDPVIKRAKYLLKKLEK
DGKGIDHNLFMFEEKVELGQIIPHDIQDLLNHINDLDINQMTPLDALIKLKYLQSLSKEK
K