ACL_RS04400

Uniprot: A9NGM3
Description: DNA recombination/repair protein RecA
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage. {ECO:0000255|HAMAP-Rule:MF_00268}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding: NP_BIND 66 73 ATP. {ECO:0000255|HAMAP-Rule:MF_00268}.
Site:
Gene names (primary): recA
Gene names (synonym):
Mass: 35,516
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA-dependent ATPase activity [GO:0008094]; single-stranded DNA binding [GO:0003697]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]
Gene ontology IDs: GO:0003684; GO:0003697; GO:0005524; GO:0005737; GO:0006281; GO:0006310; GO:0008094; GO:0009432
Chain: CHAIN 1 331 Protein RecA. /FTId=PRO_1000078659.
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the RecA family. {ECO:0000255|HAMAP-Rule:MF_00268}.
Protein families: RecA family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NGM3
MEROPS:
EnsemblBacteria KO: ABX81503
UniPathway: K03553
CDD:
Gene3D: cd00983
HAMAP: 3.30.250.10;3.40.50.300
InterPro: MF_00268
PANTHER: IPR003593;IPR013765;IPR020584;IPR027417;IPR020588;IPR023400;IPR020587
PIRSF: PTHR22942:SF1
PRINTS:
PROSITE: PR00142
Pfam: PS00321;PS50162;PS50163
ProDom: PF00154
SMART:
SUPFAM: SM00382
TIGRFAMs: SSF52540;SSF54752

923963-924959(-)

>nucleotide sequence
CTATTTTGTTAATTTAAAATGCGTTCTAACCTTTTTTTCTAACTCGTTTAGAAGTTCTGG
TTTATCTTCTAAATATTGTTTTGCATTGTCACGACCTTGGCCAAGTTTTTCTTCACCAAT
GTTATACCATGCACCACTTTTATTAACTAAATTAAGTTCTACTGAAAGGTCAAGTACTTC
ACCACTTCTAGAAATACCAGTACCATACATAATATCAATAGATGCTGTTTTTAGTGGTGG
TGCCACTTTAGATTTAACAACTTTCACATTTGATTTAATACCTATCATCTCACTACCTTG
TTTAATCGCTTCAGCACGTCTAATTTCTAATCTCACTGATGAGAAGAATTTAAGTGCACG
ACCACCCGGGGTTGTTTCTGGGTTACCAAACATCACGCCAACTTTTTCTCTAATTTGATT
GATGAAAATTGCTACAACATTTGATTTTGAGATAACGCCTGACATTTTGCGCATAGCCTG
TGACATCATTCTTGCTTGTAAGCCTACATGGTTTGCAGACATATCACCAGCAATTTCAGC
TTCTGGTACTAAAGCCGCTACAGAGTCTATGACGATCATATCAATAGATCCACTCTTAAT
TAGAGCCTCAGCTATATCAAGTGCTTGTTCACCTGTATCTGGTTGAGATAACACTAAATT
ATCTATATCCACACCTAGTGCTTTTGCATAATTTGGATCAAGTGCGTGCTCAGCATCGAT
AAACGCTACTGTACCACCTTGCTTTTGTGCACTTGCCATAGCATGTAAAGTAAGTGTTGT
CTTACCACTTGACTCAGGTCCATAAACTTCAATAATTCTTCCTCTAGGATAACCACCAAT
ACCTAATGCTATATCTAATGCTATAGAACCAGATGGAATTGCTTCTATTGAATGGTCAGC
ACCATCACCTAATTTCATAATCGACCCTTTACCAAATTGTTTTTCAATTTGTTTAAGGGC
TAATTCTAGTGCTTGTTGTTTTTTATTATCGCTCAT

>protein sequence
MSDNKKQQALELALKQIEKQFGKGSIMKLGDGADHSIEAIPSGSIALDIALGIGGYPRGR
IIEVYGPESSGKTTLTLHAMASAQKQGGTVAFIDAEHALDPNYAKALGVDIDNLVLSQPD
TGEQALDIAEALIKSGSIDMIVIDSVAALVPEAEIAGDMSANHVGLQARMMSQAMRKMSG
VISKSNVVAIFINQIREKVGVMFGNPETTPGGRALKFFSSVRLEIRRAEAIKQGSEMIGI
KSNVKVVKSKVAPPLKTASIDIMYGTGISRSGEVLDLSVELNLVNKSGAWYNIGEEKLGQ
GRDNAKQYLEDKPELLNELEKKVRTHFKLTK