ACL_RS04855


  Uniprot: A9NGW2
Description: ATP synthase subunit beta
EC number: 3.6.3.14
Annotation score: 3 out of 5
Miscellaneous [CC]: 
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out). {ECO:0000255|HAMAP-Rule:MF_01347}.
Cofactor: 
Enzyme regulation: 
Function [CC]: FUNCTION: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. {ECO:0000255|HAMAP-Rule:MF_01347}.
Pathway: 
Active site: 
Binding site: 
Calcium binding: 
DNA binding: 
Metal binding: 
Nucleotide binding: NP_BIND 149 156 ATP. {ECO:0000255|HAMAP-Rule:MF_01347}.
Site: 
Gene names (primary): atpD
Gene names (synonym): 
Mass: 50,459
Subunit structure [CC]: SUBUNIT: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains. {ECO:0000255|HAMAP-Rule:MF_01347}.
Gene ontology (GO): plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP hydrolysis coupled proton transport [GO:0015991]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]
Gene ontology IDs: GO:0005524; GO:0005886; GO:0015991; GO:0042777; GO:0045261; GO:0046933
Chain: CHAIN 1 460 ATP synthase subunit beta. /FTId=PRO_0000339467.
Signal peptide: 
Domain [CC]: 
Sequence similarities: SIMILARITY: Belongs to the ATPase alpha/beta chains family. {ECO:0000255|HAMAP-Rule:MF_01347}.
Protein families: ATPase alpha/beta chains family
Coiled coil: 
Domain [FT]: 
Motif: 
Region: 
EMBL: CP000896
ProteinModelPortal: 
MEROPS: 
EnsemblBacteria KO: ABX81592
UniPathway: K02112
CDD: 
Gene3D: 
HAMAP: 1.10.1140.10;3.40.50.300
InterPro: MF_01347
PANTHER: IPR003593;IPR020003;IPR005722;IPR000793;IPR000194;IPR004100;IPR024034;IPR027417
PIRSF: 
PRINTS: 
PROSITE: 
Pfam: PS00152
ProDom: PF00006;PF02874
SMART: 
SUPFAM: SM00382
TIGRFAMs: SSF47917;SSF50615;SSF52540
1005328-1006711(-)

>nucleotide sequence
TCATAGTTTTTTAGCCTTAGCAATTGCATCATCAATCGTACCAACAAGTAAGAATGCTTC
TTCAGGTAAATCATCATGTTTACCTTGTAAGATTTCTTTAAATCCCCGAATGGTTTCTCT
AATTGGGACGAAACTACCAGTTTGACCGGTAAATCTTTCAGCGACGTGCATATTTTGACT
TAAGAAGTTTTGAATACGTCTTGCACGGTGTACAACTAATTTGTCATCATCACTTAATTC
ATCCATACCTAGGATGGCAATAATATCTAAGAGTTCATGATATCTTTGTAGCATACGTTG
TACTTCACGTGCAGTGTCATAATGTTCTTGGCCTACAACAGAAGGTGTAAGTGCTCTAGA
TGTGGACCCAAGCGGATCAATTGCTGGATATATGCCATCCTCAGTTAGTTTTCTACTTAA
GGCTGTAGTCGCATCAAGATGCGAAAAAACTGTTGCTGGAGCAGGGTCTGTGTAGTCATC
TGCTGGTACATAGACGGCTTGAATGGAGGTAATAGATCCGTATCTGGTTGATGTAATACG
TTCTTGAAGTTTACCCATTTCCGTTGCTAGTGTTGGTTGATAACCAACAGCAGATGGCAT
TCTTCCAAGTAGGGCTGATATTTCAGAACCTGCTTGAATGTATCTATAAATGTTATCAAT
AAATAGCAAGACGTTTTGTTTTTCACCATCTCTAAAATACTCCGCAAGGGTAAGTCCTGT
TAAAGCAACCCTTAATCTTGCACCCGGTGGTTCATTCATTTGACCAAAGACCAGTGCAGT
TTTATCTAAAACACCAGAGTCTTTCATCTCATGATAGAGTTCATGACCTTCACGGACACG
TTCACCAACCCCTGTAAAGACAGAAATACCACCATGGTTTTTGGCAACGTTATGTATCAT
TTCTTGAATTAATACGGTTTTACCAACACCGGCACCACCAAATAAACCAATTTTACCACC
TTTAATATATGGGGCAATTAAGTCTATGACTTTGATACCTGTTTCTAAAATTTCAGTTTC
TCCGCCTAAATCATGGAAATCAGGAGGTAACTTATGGATTGGCATGTATCTTTTTGTATC
TACTTCATCTAGACCATCCATTGGTTTACCTAAAACGTTTAACATGCGCCCTAATACTTT
TTTACCTACTGGTACTTTAATTGGAGATAGTGTACCGATAACTTCCATACCACGAGCTAA
CCCATCGGTTGCTTCAAGTGAGATTGTACGAACCATATGATTTCCTAAGTGGGAAGCCAC
TTCTAGTGTTCTTGTTTCAGTTTCACTTAATCTAACCTCAAGTGCATCGTTGATATTCGG
AAGTTCATCCATAAAAGAAACATCCACAACAGGTCCTATGATCGCTACAATTTTTCCTTT
CAT


>protein sequence
MKGKIVAIIGPVVDVSFMDELPNINDALEVRLSETETRTLEVASHLGNHMVRTISLEATD
GLARGMEVIGTLSPIKVPVGKKVLGRMLNVLGKPMDGLDEVDTKRYMPIHKLPPDFHDLG
GETEILETGIKVIDLIAPYIKGGKIGLFGGAGVGKTVLIQEMIHNVAKNHGGISVFTGVG
ERVREGHELYHEMKDSGVLDKTALVFGQMNEPPGARLRVALTGLTLAEYFRDGEKQNVLL
FIDNIYRYIQAGSEISALLGRMPSAVGYQPTLATEMGKLQERITSTRYGSITSIQAVYVP
ADDYTDPAPATVFSHLDATTALSRKLTEDGIYPAIDPLGSTSRALTPSVVGQEHYDTARE
VQRMLQRYHELLDIIAILGMDELSDDDKLVVHRARRIQNFLSQNMHVAERFTGQTGSFVP
IRETIRGFKEILQGKHDDLPEEAFLLVGTIDDAIAKAKKLW






















© Fisunov Lab of Proteomics, 2016.