ACL_RS04885

Uniprot: A9NGW8
Description: F-type H+-transporting ATPase subunit A
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. {ECO:0000256|HAMAP-Rule:MF_01393}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): atpB
Gene names (synonym):
Mass: 25,638
Subunit structure [CC]: SUBUNIT: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains. {ECO:0000256|HAMAP-Rule:MF_01393}.
Gene ontology (GO): integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, coupling factor F(o) [GO:0045263]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]
Gene ontology IDs: GO:0005886; GO:0016021; GO:0042777; GO:0045263; GO:0046933
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the ATPase A chain family. {ECO:0000256|HAMAP-Rule:MF_01393}.
Protein families: ATPase A chain family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NGW8
MEROPS:
EnsemblBacteria KO: ABX81598
UniPathway: K02108
CDD:
Gene3D:
HAMAP: 1.20.120.220
InterPro: MF_01393
PANTHER: IPR000568;IPR023011
PIRSF: PTHR11410
PRINTS:
PROSITE: PR00123
Pfam: PS00449
ProDom: PF00119
SMART:
SUPFAM:
TIGRFAMs: SSF81336

1010402-1011104(-)

>nucleotide sequence
TCATATGCCTCCTTTGATTTCTAAATCACTTTCTTCTATTTTATTTGATGAAAATACTGT
TGTAAGTAATACAAACACGATGGTTTGAATCACTCCAAATCCTATATCGAATATCGCATG
TGCTACTGGTCCTGCAATCACAGTTGCTGGTCCTGATACCGCATATATTAGTGTAAGTAC
TGCTGCTCCGGATGCGATGTTACCAAATAGTCGCATCGTCATGGAGATTAACGGGGTTAA
GTCACTTAATATATTTAAGGGAATCATGACTGGTGAAAACCACCACATAGGTCCCATTAA
AGTCTTAAAGTGCTTGAGTCCTTTTGATCTTAATCCAACTGACTGTATTGTTATAACACT
TACAATTGCAAATGCTAATGTGACCGTTGCATATTTTGTTGGTGTATCTAATAAGAATAG
TCCAGATATGTTGGATAAAAATATAAAGATAGCAAGGCTTAGTATAATCGGTGCAAGCAT
CTTCCAGTGTTTACCAATGTTATTTTTAGCATAGTTGTTCATAAACTGAACAAATGTAAT
TATACCTGTCATAACTTTGCCTGGATTATCACCAATCTTTAATTTGCTGACTTTATGCCT
GATAATTAGTGAACATATCAGTACAACAAGAACAATGATGAAACTTGACCATATGTAGTA
GGGAATAGTTAATAAATATCTAATCACTTGTTCTATCATCAT

>protein sequence
MMIEQVIRYLLTIPYYIWSSFIIVLVVLICSLIIRHKVSKLKIGDNPGKVMTGIITFVQF
MNNYAKNNIGKHWKMLAPIILSLAIFIFLSNISGLFLLDTPTKYATVTLAFAIVSVITIQ
SVGLRSKGLKHFKTLMGPMWWFSPVMIPLNILSDLTPLISMTMRLFGNIASGAAVLTLIY
AVSGPATVIAGPVAHAIFDIGFGVIQTIVFVLLTTVFSSNKIEESDLEIKGGIW