ACL_RS05130

Uniprot: A9NH17
Description: phosphoglucosamine mutase
EC number: 5.4.2.10
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. {ECO:0000256|SAAS:SAAS00358409}.
Cofactor: COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|SAAS:SAAS00609101};
Enzyme regulation:
Function [CC]: FUNCTION: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. {ECO:0000256|SAAS:SAAS00551243}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): glmM
Gene names (synonym):
Mass: 48,102
Subunit structure [CC]:
Gene ontology (GO): magnesium ion binding [GO:0000287]; phosphoglucosamine mutase activity [GO:0008966]; carbohydrate metabolic process [GO:0005975]
Gene ontology IDs: GO:0000287; GO:0005975; GO:0008966
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the phosphohexose mutase family. {ECO:0000256|RuleBase:RU004326, ECO:0000256|SAAS:SAAS00551227}.
Protein families: Phosphohexose mutase family
Coiled coil:
Domain [FT]: DOMAIN 4 129 PGM_PMM_I. {ECO:0000259|Pfam:PF02878}.; DOMAIN 158 243 PGM_PMM_II. {ECO:0000259|Pfam:PF02879}.; DOMAIN 247 355 PGM_PMM_III. {ECO:0000259|Pfam:PF02880}.; DOMAIN 364 411 PGM_PMM_IV. {ECO:0000259|Pfam:PF00408}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NH17
MEROPS:
EnsemblBacteria KO: ABX81647
UniPathway: K03431
CDD:
Gene3D: cd05802
HAMAP: 3.30.310.50;3.40.120.10
InterPro:
PANTHER: IPR005844;IPR016055;IPR005845;IPR005846;IPR005843;IPR016066;IPR005841;IPR006352
PIRSF:
PRINTS:
PROSITE: PR00509
Pfam: PS00710
ProDom: PF02878;PF02879;PF02880;PF00408
SMART:
SUPFAM:
TIGRFAMs: SSF53738;SSF55957

1065149-1066460(-)

>nucleotide sequence
TTACAATCTCCCCAGATTTTGTATCTTAGTTACAAGTAGTCCCATGTACTTATCGAGTTC
TAAGATATCTTGACAACTTATTGTAACACGAACTAAAGGTTCTGTACCACTAGGACGTAC
TAATAATAAAGAATCTTCTGATAGATTTCTTCTAACTTCTTCTACTAGTTTAATTATTTC
GGGATGTTTGAGTACTTCTTTATCAACATTTTTGATGTTGACCATTTTTTGAGGATACAT
TTCTACTTCCTTTGTATAATCTTTTAGTGATGTTTTATGTTCTTCTAAGATCTTTAGTAT
ATAAACACCTGCAAATAAACCATCACCTGAAGGCAGTAAGTCATTTATGATGATATGTCC
TGAATTTTCTCCACCTATGCTTAAATCGTGATTCATAATTTCTTCAGATACATATTTATC
TCCTACTGGAGTTTGAAGTACTTTGATACCTAATGTTTTAAATGCTTTAAGCATACCAGG
ATTACTCATTTGAGTTAAGACTACTGTATCTTTTTTAAGTTTTCCTTTAGATTTTAAGTA
CTTAGCTATGATGTAGACAATGTAGTCTCCATCAAATGTAGTACCATCCTTGTCTACAAC
TAAAAGACGATCCCCATCACCATCAAAAGATAGTCCAATGTCTGAACCGTTACTTTTAAC
TGCATTAATGATAGATTCTAAGTGAGTTGATCCTACATTTAAGTTAATGTTTAACCCATC
TGGCCTGTTACCTATTTGATAGGTATGTGATGCAAAAGACTCTATTACTTTTTTAGAAAT
AAGATAGTTAGCTCCATTTGCAGAATCATAGGTTATTTTCATAGATGTTTTAGGAATATT
TAAATCTTGATAGACATTTATATAAATATCTTCTACATCATGTGTTATTTCTATTGAACC
TAGTTTCGTTGAAGATAAAACCTCATTATCATCAATGTAGGTTTCTAAATTAAGTTCTTC
TTCATCAAGCATTTTATAACCTGATTTAATGACTTTAATACCATTATCAGTATATGGGTT
ATGAGATGCAGTGATCATAACTCCTATGATATCTTTCACTTTAGAGTAATAAGCAATCAT
AGGTGTTGAAACAACACCTGCAATTTTTACATTTACTCCAGCTAGTGCTGCACCGTATGC
AACACCATATGCAAGCATGTTTGAAGATAGTCTAGTATCTTGACCAATGATGATTTCACT
AGGACTAAACTTTTTAGCTATGGCTTGACCTAATTTAAACGCTAGTTTTGAATTTAATTT
TTCAAAAGCGATACCGCGTATCCCATCGGTACCAAAATAATTATTTTTCAT

>protein sequence
MKNNYFGTDGIRGIAFEKLNSKLAFKLGQAIAKKFSPSEIIIGQDTRLSSNMLAYGVAYG
AALAGVNVKIAGVVSTPMIAYYSKVKDIIGVMITASHNPYTDNGIKVIKSGYKMLDEEEL
NLETYIDDNEVLSSTKLGSIEITHDVEDIYINVYQDLNIPKTSMKITYDSANGANYLISK
KVIESFASHTYQIGNRPDGLNINLNVGSTHLESIINAVKSNGSDIGLSFDGDGDRLLVVD
KDGTTFDGDYIVYIIAKYLKSKGKLKKDTVVLTQMSNPGMLKAFKTLGIKVLQTPVGDKY
VSEEIMNHDLSIGGENSGHIIINDLLPSGDGLFAGVYILKILEEHKTSLKDYTKEVEMYP
QKMVNIKNVDKEVLKHPEIIKLVEEVRRNLSEDSLLLVRPSGTEPLVRVTISCQDILELD
KYMGLLVTKIQNLGRL