ACL_RS05360

Uniprot: A9NH64
Description: modification methylase
EC number: 2.1.1.72
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N-6-methyladenine in DNA. {ECO:0000256|RuleBase:RU361257}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site: BINDING 7 7 S-adenosyl-L-methionine. {ECO:0000256|PIRSR:PIRSR000398-1}.; BINDING 11 11 S-adenosyl-L-methionine; via amide nitrogen. {ECO:0000256|PIRSR:PIRSR000398-1}.; BINDING 52 52 S-adenosyl-L-methionine. {ECO:0000256|PIRSR:PIRSR000398-1}.; BINDING 186 186 S-adenosyl-L-methionine. {ECO:0000256|PIRSR:PIRSR000398-1}.
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary):
Gene names (synonym):
Mass: 32,436
Subunit structure [CC]:
Gene ontology (GO): nucleic acid binding [GO:0003676]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]
Gene ontology IDs: GO:0003676; GO:0009007
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family. {ECO:0000256|RuleBase:RU361257}.
Protein families: N(4)/N(6)-methyltransferase family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NH64
MEROPS:
EnsemblBacteria KO: ABX81694
UniPathway: K06223
CDD:
Gene3D:
HAMAP: 1.10.1020.10;3.40.50.150
InterPro:
PANTHER: IPR023095;IPR002052;IPR012263;IPR012327;IPR029063
PIRSF:
PRINTS: PIRSF000398
PROSITE: PR00505
Pfam: PS00092
ProDom: PF02086
SMART:
SUPFAM:
TIGRFAMs: SSF53335

1117974-1118802(-)

>nucleotide sequence
TTATTCATAGTTAATGATAATGACTTCTTCTACATTTCCACGACCATTTGGATTTGAATT
TACAACACGCTTTGCAGGGACAACATGTATCTTGTAATCTTTATAAAGATTTCTAATAAA
GTCTGTATTATGATTACTTAACATCACTTTCACACCACGCTTATCCAATGCTTTAAATGT
TTCAAATAATCGTATTTGATCTTCTTTATTAAAATCGCCTTGAGCATAGGATGTAAAGGA
ATTTTTATCTTCCCAAGGATCATATGGTGGATCAAAGTACACAAAGTCATCTTTTTTAGC
ATCCTTAACTACTTCTTCAAAATCTAGATTGTTTATATAGACCTCATTAGATCTTAAGTA
GTAATGAATGCTTGTTATGTTATCTAAATCATAAAGTTTTACCTTATCTCTTTTTCCTGA
AGGTACATTATAAAATCCTTTTTTATTGACTCTATATAAACCATTAAATCCTGCTTTATT
TAAGTAAATTACTCTTGCGGCTTTTTCAAATGGTTCAAGTGCACTATACCCTTCTAATCT
GTCCATCTCTCTAACTTCATAATAATATGTTTCATTATGATTCTTTTCATGATGATCTAA
CTTTAAAAGTAATTTCTTAAATTGTTCATTATCTTGTAGAGATATGTAAACAGATATTAA
ATCCTTGTTTACATCATTGATATAGGCTACATTAGGAGCAAACTCAAACAAGACTGCACC
AGCACCAACAAATGGCTCATAATATGCATTAAAGTGATAAGGCATAAGTTCTTTGATATG
ACTTAACATTTGTCTTTTCCCACCAACCCATTTTAATACCGGTAACAT

>protein sequence
MLPVLKWVGGKRQMLSHIKELMPYHFNAYYEPFVGAGAVLFEFAPNVAYINDVNKDLISV
YISLQDNEQFKKLLLKLDHHEKNHNETYYYEVREMDRLEGYSALEPFEKAARVIYLNKAG
FNGLYRVNKKGFYNVPSGKRDKVKLYDLDNITSIHYYLRSNEVYINNLDFEEVVKDAKKD
DFVYFDPPYDPWEDKNSFTSYAQGDFNKEDQIRLFETFKALDKRGVKVMLSNHNTDFIRN
LYKDYKIHVVPAKRVVNSNPNGRGNVEEVIIINYE