ACL_RS05690

Uniprot: A9NHB9
Description: di-trans,poly-cis-decaprenylcistransferase
EC number: 2.5.1.-
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor: COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-Rule:MF_01139}; ; Note=Binds 2 magnesium ions per subunit. {ECO:0000256|HAMAP-Rule:MF_01139}
Enzyme regulation:
Function [CC]: FUNCTION: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. {ECO:0000256|HAMAP-Rule:MF_01139}.
Pathway:
Active site: ACT_SITE 15 15 {ECO:0000256|HAMAP-Rule:MF_01139}.; ACT_SITE 63 63 Proton acceptor. {ECO:0000256|HAMAP-Rule:MF_01139}.
Binding site: BINDING 20 20 Substrate. {ECO:0000256|HAMAP-Rule:MF_01139}.; BINDING 28 28 Substrate. {ECO:0000256|HAMAP-Rule:MF_01139}.; BINDING 32 32 Substrate. {ECO:0000256|HAMAP-Rule:MF_01139}.; BINDING 64 64 Substrate. {ECO:0000256|HAMAP-Rule:MF_01139}.; BINDING 66 66 Substrate. {ECO:0000256|HAMAP-Rule:MF_01139}.; BINDING 170 170 Substrate. {ECO:0000256|HAMAP-Rule:MF_01139}.
Calcium binding:
DNA binding:
Metal binding: METAL 15 15 Magnesium. {ECO:0000256|HAMAP-Rule:MF_01139}.; METAL 189 189 Magnesium. {ECO:0000256|HAMAP-Rule:MF_01139}.
Nucleotide binding:
Site:
Gene names (primary): uppS
Gene names (synonym):
Mass: 25,964
Subunit structure [CC]: SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01139}.
Gene ontology (GO): magnesium ion binding [GO:0000287]; prenyltransferase activity [GO:0004659]
Gene ontology IDs: GO:0000287; GO:0004659
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the UPP synthase family. {ECO:0000256|HAMAP-Rule:MF_01139}.
Protein families: UPP synthase family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NHB9
MEROPS:
EnsemblBacteria KO: ABX81749
UniPathway: K00806
CDD:
Gene3D: cd00475
HAMAP: 3.40.1180.10
InterPro: MF_01139
PANTHER: IPR001441;IPR018520
PIRSF: PTHR10291
PRINTS:
PROSITE:
Pfam: PS01066
ProDom: PF01255
SMART:
SUPFAM:
TIGRFAMs: SSF64005

1208042-1208711(-)

>nucleotide sequence
TTATAATCCCCCAAAACGTCTTTGTCGTTTTGAATACTCTTTGAGTGCCCTATCAAAATG
TTTGATTTTAAATGCTGGCCAGTATCTTTTTGTAAAATATAATTCCGCGTATGCTATTTG
CCATAGTAAGAAGTTAGATAACCTTTGTTCTCCACCTGTGCGAATTAATAGATCTACTGG
TCTATTTACCATCAAATGTTGTTCTAGATGTGCTTCATCTATAACATCCATTTGTTTGAT
GGCAGTAATGAGTTCATCATAACTACCGTAATCAATACATACATTAATTGTCATACCTGT
AAAATCTTTTGTTTCATCTTCCAGACTATCCATTAATTCTAAAATATCTTTGGATAATCT
ATCTTTTCTTCCTTTAAAACGAATACGGATATTTGCTTGACAGATTCTAGCTTTATTTTT
ACCTACAACTTCGATTGGTTTAGTCATTAAATATTCGACTTCATCCTGTGGTCTTTTCCA
GTTTTCAGTTGAAAAAGCATAAACAGTGAGTTCTTCTATACCTCTTTTATTTGCATGTTC
GGCAATTTTAGCCAGATTTAGGCCACCTTGATAGTGACCTGCTGATCTTGGTAGATGTAA
TCTTTTAGCCCACCTGCCATTGCCATCTAAAATAATGGCGACGTGTTTTGGTAGATTTTG
AATTTTCAT

>protein sequence
MKIQNLPKHVAIILDGNGRWAKRLHLPRSAGHYQGGLNLAKIAEHANKRGIEELTVYAFS
TENWKRPQDEVEYLMTKPIEVVGKNKARICQANIRIRFKGRKDRLSKDILELMDSLEDET
KDFTGMTINVCIDYGSYDELITAIKQMDVIDEAHLEQHLMVNRPVDLLIRTGGEQRLSNF
LLWQIAYAELYFTKRYWPAFKIKHFDRALKEYSKRQRRFGGL