ACL_RS05740

Uniprot: A9NHC9
Description: integrase/recombinase, XerD-like protein
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site: ACT_SITE 147 147 {ECO:0000256|HAMAP-Rule:MF_01808}.; ACT_SITE 171 171 {ECO:0000256|HAMAP-Rule:MF_01808}.; ACT_SITE 245 245 {ECO:0000256|HAMAP-Rule:MF_01808}.; ACT_SITE 248 248 {ECO:0000256|HAMAP-Rule:MF_01808}.; ACT_SITE 271 271 {ECO:0000256|HAMAP-Rule:MF_01808}.; ACT_SITE 280 280 O-(3'-phospho-DNA)-tyrosine intermediate. {ECO:0000256|HAMAP-Rule:MF_01808}.
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): xerC
Gene names (synonym):
Mass: 35,608
Subunit structure [CC]: SUBUNIT: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD. {ECO:0000256|HAMAP-Rule:MF_01808, ECO:0000256|SAAS:SAAS00608017}.
Gene ontology (GO): cytoplasm [GO:0005737]; DNA binding [GO:0003677]; tyrosine-based site-specific recombinase activity [GO:0009037]; cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; transposition, DNA-mediated [GO:0006313]
Gene ontology IDs: GO:0003677; GO:0005737; GO:0006313; GO:0007049; GO:0007059; GO:0009037; GO:0051301
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the 'phage' integrase family. XerC subfamily. {ECO:0000256|SAAS:SAAS00608022}.
Protein families: 'phage' integrase family, XerC subfamily
Coiled coil:
Domain [FT]: DOMAIN 5 86 Integrase_SAM-like_N. {ECO:0000259|Pfam:PF02899}.; DOMAIN 112 285 Phage_integrase. {ECO:0000259|Pfam:PF00589}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NHC9
MEROPS:
EnsemblBacteria KO: ABX81759
UniPathway: K03733
CDD:
Gene3D:
HAMAP: 1.10.150.130;1.10.443.10
InterPro: MF_01808
PANTHER: IPR011010;IPR013762;IPR002104;IPR023109;IPR004107;IPR023009
PIRSF:
PRINTS:
PROSITE:
Pfam:
ProDom: PF02899;PF00589
SMART:
SUPFAM:
TIGRFAMs: SSF56349

1214988-1215909(-)

>nucleotide sequence
TCACTTAGTTTTCTCATTATGTTGATTCCTTGGATGCGTCTGCATGTATTTTTCTTTTAA
TTGTTCTTTTGAAACATGTGTATAAATTTGAGTGGATTTTAAATGCTCATGACCTAAGAG
TTCTTGTACAACTCTTAAATCTGCGCCATGATTTAGCATCGTAGTTGCGAAAGCATGTCT
TAACATATGCGGATGTATCGCATAGGTTTCACCACTATCTTTAATCATTTGATTTAAGAT
AACTCTTAAACCTCTTACAGTAAGTGGTCCACCTTTATAATTAATAAACAGTTTTTGTTG
ATTGGTATCATCACCCTTAGAAAGTAGGGTGACTCTTACAAACGATAGATAATGTCTAAT
TTCTTCAATTAACTTCTCATGTAATATGATATATCTATCTTTCTTACCCTTACCATGGAT
AAGTATTTGACCACTCGATAAATAAATATCTTTAATTTCTAAATTGATGAGTTCACTTGC
ACGAACACCACAACTATATAGTAAATCTAAAATGACTAGATTTCTATAGCCTAAGGGCTT
GGATGTGTCAATGGAATCAAATAGATAATTAATTGCCTCTTCATCAATAATATGGGGTAG
TGTTTTAGCTACTTTAGGCGCTTTGATGTCACTAAAGATATTTTCTTCTATAAGTTCTTT
AAATATTAAATAATTATAAAAGTTCTTTAAACTAGATAGTTTTCTAGCGATTGTTTTTTT
CTTAAAGTCTTGGTTATCTAAATAAGATATATAGTTACGTGCTAAACGAGGTCGTCTAGC
ACCTAATAAATCTTTGGCTAGTCCCTCTTTAATTAAAAAGTCTTCAAACCCTTTGACATC
GTTGATGTAACTTATAGCTGTGTGTTCACTAAAGTTCTTTTCAATGATGAGGTAATCTTT
GTAATCAGAGATAATATCCAT

>protein sequence
MDIISDYKDYLIIEKNFSEHTAISYINDVKGFEDFLIKEGLAKDLLGARRPRLARNYISY
LDNQDFKKKTIARKLSSLKNFYNYLIFKELIEENIFSDIKAPKVAKTLPHIIDEEAINYL
FDSIDTSKPLGYRNLVILDLLYSCGVRASELINLEIKDIYLSSGQILIHGKGKKDRYIIL
HEKLIEEIRHYLSFVRVTLLSKGDDTNQQKLFINYKGGPLTVRGLRVILNQMIKDSGETY
AIHPHMLRHAFATTMLNHGADLRVVQELLGHEHLKSTQIYTHVSKEQLKEKYMQTHPRNQ
HNEKTKW