ACL_RS06175

Uniprot: A9NHL6
Description: molecular chaperone GroEL
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. {ECO:0000255|HAMAP-Rule:MF_00600}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): groL
Gene names (synonym): groEL
Mass: 58,267
Subunit structure [CC]: SUBUNIT: Oligomer of 14 subunits composed of two stacked rings of 7 subunits. {ECO:0000255|HAMAP-Rule:MF_00600}.
Gene ontology (GO): cytoplasm [GO:0005737]; ATP binding [GO:0005524]; protein refolding [GO:0042026]
Gene ontology IDs: GO:0005524; GO:0005737; GO:0042026
Chain: CHAIN 1 536 60 kDa chaperonin. /FTId=PRO_1000082460.
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the chaperonin (HSP60) family. {ECO:0000255|HAMAP-Rule:MF_00600}.
Protein families: Chaperonin (HSP60) family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NHL6
MEROPS:
EnsemblBacteria KO: ABX81846
UniPathway: K04077
CDD:
Gene3D:
HAMAP: 1.10.560.10;3.50.7.10
InterPro: MF_00600
PANTHER: IPR001844;IPR002423;IPR027409;IPR027413
PIRSF:
PRINTS:
PROSITE: PR00298
Pfam:
ProDom: PF00118
SMART:
SUPFAM:
TIGRFAMs: SSF52029

1297616-1299227(-)

>nucleotide sequence
TTAATACATTGGTTGTGTAGGTATATTTTGGTCTTTATCTTTAATTTCCACAACTGCTGC
TTCAGAAGTGATCATTAATGCTCCAATACTTGATGCATTAAGAATTGCATTTCTTGTAAC
TTTAGTTGGGTCAATGATACCTTCTTTCAGCATATTAACCCACTTACCTTCTTTAGCATC
AAACCCATAGTTTTTATTTTGTTTTCTTTGTTCTGTTAATATATCTTGGCCATCAAAACC
AGCATTTTCAGCTATTTGATAAAGTGGTTCCGATAATGAATCTAAGACAGCAAGTATGCC
TTTATATATATCTATATGGCTATCTTTAAGTGTTTCTTTCAGTTCAGTTTGTATATCTAC
TAAAACGGAACCACCACCAGCAACAATACCTTCTAAAATTGCAGCCTTTGTTGCATTAAG
CGCATCTTCTATTCTTAATTTCTTTTCTTTTAATTCTGCTTCAGTAGCTGCACCTACTTT
GATGATTGCAACACCTCCAGCAAGTTTTGCAAGTCTTTCTTGTAGGCGTTTTTTATCATA
ATCTGATGTAGATGAATTAATTTGTGCTTCAATTTCCAAAATACGCTTGTCAATAGCATC
TTTAGTGCCATGACCACCGATAAGTGTTGTTGTATCTTTTTTAACAACAGCTTTTTGGAC
CAGTCCAAGATCTTCTAATTTAATTTCTTGAAGCTTCATCTGTAAATCTTTTGCATAGAA
GGTTGCACCAGTTAATATTGCAATATCATTTAACATGTCTTTTTGGTTATCACCAAAGCC
AGGAGCTTTGGTTGCAACGACATTAAACGTACCTCTAAGTTTGTTTAGAATCAGTGTAGA
TGTCACTTCATTTTCTATATCATCAGCGATAATTAATAGTGGCTTATTTGCTTTAACAAC
TTGCTCTAATATCGGTAAGATATCTTGAATTGTAGATATCTTTTGATCAGTTACAAGTAC
ATGTGGATTTTCTAATTCAACTGTCATTGTTTCTCGATCACTTACAAAGTAAGGTGATAT
ATACCCCTTATCATATTGCATACCTTCAACAACTTCCAGTTCTGTTTCAAAACCTTTAGA
CTCATCAACTGAAATCACACCATTTTTTGAAACCTTATCCATCGCTTCGGCAATTATTTT
ACCGATTTCTCTAGAGGATGCACTAATGCTTGCTACATTTTCTATATCTTCACTAGTTTC
AACCGGTCTAGATTTTTCTAATAACTTTTGTGAAACTTCTTTACCAGCACGTAAAATACC
TTCTCTAACTAAGACTGGATTTGCACCATTATCCACAGCTTTAAATCCCTTATGGATAAT
GGATTGTGCAAGTAGTGTTGCAGTTGTTGTACCATCACCAGCAACATCATTTGTTTTAGA
TGCAACTTCATATAATAATTTTGCTCCCATATTTTCATATGGATCTTTTAATTCAATCTC
TTTTGCAATGGATACACCATCATTTGTAATCAGTGGAGAACCGTATCCTTTGTCCAAGAC
TACATTTCTTCCTTTTGGCCCAAGGGTGATTTTTACTGTATTAGCAAGTAAATCTACCCC
TTTTAGTAAAGATTGTTTAGCATCTTTACCATAACGAATTTCTTTACTCAT

>protein sequence
MSKEIRYGKDAKQSLLKGVDLLANTVKITLGPKGRNVVLDKGYGSPLITNDGVSIAKEIE
LKDPYENMGAKLLYEVASKTNDVAGDGTTTATLLAQSIIHKGFKAVDNGANPVLVREGIL
RAGKEVSQKLLEKSRPVETSEDIENVASISASSREIGKIIAEAMDKVSKNGVISVDESKG
FETELEVVEGMQYDKGYISPYFVSDRETMTVELENPHVLVTDQKISTIQDILPILEQVVK
ANKPLLIIADDIENEVTSTLILNKLRGTFNVVATKAPGFGDNQKDMLNDIAILTGATFYA
KDLQMKLQEIKLEDLGLVQKAVVKKDTTTLIGGHGTKDAIDKRILEIEAQINSSTSDYDK
KRLQERLAKLAGGVAIIKVGAATEAELKEKKLRIEDALNATKAAILEGIVAGGGSVLVDI
QTELKETLKDSHIDIYKGILAVLDSLSEPLYQIAENAGFDGQDILTEQRKQNKNYGFDAK
EGKWVNMLKEGIIDPTKVTRNAILNASSIGALMITSEAAVVEIKDKDQNIPTQPMY