ACL_RS06350

Uniprot: A9NHP8
Description: spermidine/putrescine ABC transporter ATP-binding protein
EC number: 3.6.3.31
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: ATP + H(2)O + polyamine(Out) = ADP + phosphate + polyamine(In). {ECO:0000256|HAMAP-Rule:MF_01726, ECO:0000256|SAAS:SAAS00035109}.
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. {ECO:0000256|HAMAP-Rule:MF_01726, ECO:0000256|SAAS:SAAS00035100}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding: NP_BIND 35 42 ATP. {ECO:0000256|HAMAP-Rule:MF_01726}.
Site:
Gene names (primary): potA
Gene names (synonym):
Mass: 41,755
Subunit structure [CC]: SUBUNIT: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). {ECO:0000256|HAMAP-Rule:MF_01726, ECO:0000256|SAAS:SAAS00035106}.
Gene ontology (GO): ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP binding [GO:0005524]; putrescine-importing ATPase activity [GO:0015594]; spermidine-importing ATPase activity [GO:0015595]
Gene ontology IDs: GO:0005524; GO:0015594; GO:0015595; GO:0043190
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. {ECO:0000256|HAMAP-Rule:MF_01726, ECO:0000256|SAAS:SAAS00548279}.; SIMILARITY: Contains 1 ABC transporter domain. {ECO:0000256|HAMAP-Rule:MF_01726, ECO:0000256|RuleBase:RU363033}.
Protein families: ABC transporter superfamily, Spermidine/putrescine importer (TC 3.A.1.11.1) family
Coiled coil:
Domain [FT]: DOMAIN 3 254 ABC transporter. {ECO:0000259|PROSITE:PS50893}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NHP8
MEROPS:
EnsemblBacteria KO: ABX81878
UniPathway: K11072
CDD:
Gene3D:
HAMAP: 3.40.50.300
InterPro:
PANTHER: IPR003593;IPR017879;IPR003439;IPR017871;IPR008995;IPR027417;IPR013611
PIRSF:
PRINTS:
PROSITE:
Pfam: PS00211;PS50893;PS51305
ProDom: PF00005;PF08402
SMART:
SUPFAM: SM00382
TIGRFAMs: SSF50331;SSF52540

1341213-1342335(+)

>nucleotide sequence
TTGAATCATAACGTGCTCATAGAGTTATCACACGTTGAAAAGAAATTTGAAGACGATCTC
ATCGTTAATGACTTAAGTCTTAAAATATATGAAAATGAGTTTGTTACACTACTTGGCCCA
TCTGGCTGTGGTAAAACAACAACACTTCGTATGATTGGCGGATTTGAAAAACCTGATAAG
GGGCATATAATAATAAATGGTAAAATATTTAATGATTTACCACCTTATGCCAGACCAATA
AATACTGTATTCCAAAAATATGCATTGTTTCCACATTTAAATGTGTTTGATAACGTTGCT
TTTGGATTAAAAAATAGGAACACAAAATATTTGTTGAAGTTCTTTAACATCGATTCATCC
TTGTCAAAAAAAGAACAATCAAACTTGATTCAAACAGGCATCGAAAAAGCAGTCAAAGAA
GCTCTAGCTTTAGTTAAGTTAGGCGGCTTTGAAAATAGAAAAATCACTCAAATGAGTGGT
GGACAACAACAACGTGTTGCACTTGCTAGAGCACTTGTCAACAAACCTCAAATTCTTCTA
CTTGATGAACCACTTGCAGCACTTGACTTAAAACTACGTCAAAACATGCAATATGAACTT
AAAGAGATGCAAAGAAAATTAGGTATTACCTTTATCTTTGTAACCCATGACCAAGAAGAA
GCTATGACAATGAGCGATAGAATTGTTGTCATGAAAGATGGCGTCATCCAACAACTTGAC
ACCCCTAAACAAATTTATAATGAGCCGGTAAATCGCTATGTAGCTACTTTTATTGGTGAA
TCAAACATCATTGATGGTGTATATAAGTCAAATAAAACAGTTACATTCTTAGGTGTAGAT
TTTGAGTGTGGACCTTATCCATTTAAAGATAACGAAAAAGTTGATGTCGTCATTAGACCT
GAAGACTTTGACGTTGTAAGTTTAGATCAAGCTAAACTTACAGGTACTGTTGTATCTTCT
ATCTTTAAAGGTGTGCATAATGAATTAGACGTTATGGTAGGAGATTATAAGTTAATGGTA
AACACCTACGAGACATATCAAGCAGGTGATACCATTGGATTAAAAATAGATCCTTATGAA
ATCCACTTAATGCCGGTATCAAATAATGAAGAAACCATTTAG

>protein sequence
LNHNVLIELSHVEKKFEDDLIVNDLSLKIYENEFVTLLGPSGCGKTTTLRMIGGFEKPDK
GHIIINGKIFNDLPPYARPINTVFQKYALFPHLNVFDNVAFGLKNRNTKYLLKFFNIDSS
LSKKEQSNLIQTGIEKAVKEALALVKLGGFENRKITQMSGGQQQRVALARALVNKPQILL
LDEPLAALDLKLRQNMQYELKEMQRKLGITFIFVTHDQEEAMTMSDRIVVMKDGVIQQLD
TPKQIYNEPVNRYVATFIGESNIIDGVYKSNKTVTFLGVDFECGPYPFKDNEKVDVVIRP
EDFDVVSLDQAKLTGTVVSSIFKGVHNELDVMVGDYKLMVNTYETYQAGDTIGLKIDPYE
IHLMPVSNNEETI