ACL_RS06395

Uniprot: A9NHQ7
Description: anaerobic ribonucleoside-triphosphate reductase activating protein
EC number: 1.97.1.-
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. {ECO:0000256|PIRNR:PIRNR000368}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): nrdG
Gene names (synonym):
Mass: 19,451
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; [formate-C-acetyltransferase]-activating enzyme activity [GO:0043365]
Gene ontology IDs: GO:0005737; GO:0043365; GO:0051539
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the organic radical-activating enzymes family. {ECO:0000256|PIRNR:PIRNR000368}.
Protein families: Organic radical-activating enzymes family
Coiled coil:
Domain [FT]: DOMAIN 28 105 Radical_SAM. {ECO:0000259|Pfam:PF04055}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NHQ7
MEROPS:
EnsemblBacteria KO: ABX81887
UniPathway: K04068
CDD:
Gene3D:
HAMAP: 3.20.20.70
InterPro:
PANTHER: IPR013785;IPR012837;IPR001989;IPR007197
PIRSF:
PRINTS: PIRSF000368
PROSITE:
Pfam: PS01087
ProDom: PF04055
SMART:
SUPFAM:
TIGRFAMs:

1349570-1350089(-)

>nucleotide sequence
TTATGAATCAGGAATAATTACAAGCTCCTGAGTCAGATTTGTTTTCTTTAAATCTATAAT
GCGTTGATTTGAACTACCACGCCACAATAGATTTAAATTTTTGAGTTGCTGTATAAACGG
ACCATCAATTAAAATATCTGCCTCTTTTAGAATTTCATGAATGAATGGACAATCCTTCTT
CTTTAGTGTCTCATAGGTGTTACCACTATAGATATTGACATCTAAACCATCTTCATGTGC
CATTTTGATTAATTCTAATACAGGCTCTGGTTGTAAGAAGGGCTCTCCACCACTAATGGT
TATGCCATGTAGTAGTGGATTTCTCTTCCATTTTTTCCTAATCTCAGTGAGCTCAATGAG
TTTACCTTCATCAAGTGCATGTGTTGATGGATTATGGCAACCAGGACATCTTAAATTGCA
GCCTTGGGTAAATACAACAAATCTTAAACCAAATCCATCCACAATAGAATCACTAATGAA
GTCATTTACGCGTAACTTAAGAGTGGAAGTGTTTGACAC

>protein sequence
VSNTSTLKLRVNDFISDSIVDGFGLRFVVFTQGCNLRCPGCHNPSTHALDEGKLIELTEI
RKKWKRNPLLHGITISGGEPFLQPEPVLELIKMAHEDGLDVNIYSGNTYETLKKKDCPFI
HEILKEADILIDGPFIQQLKNLNLLWRGSSNQRIIDLKKTNLTQELVIIPDS