ACL_RS06690

Uniprot: A9NHW4
Description: glutamine--tRNA ligase
EC number: 6.1.1.18
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). {ECO:0000256|SAAS:SAAS00023079}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): glnS
Gene names (synonym):
Mass: 62,879
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; glutaminyl-tRNA aminoacylation [GO:0006425]
Gene ontology IDs: GO:0004819; GO:0005524; GO:0005737; GO:0006425
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family. {ECO:0000256|RuleBase:RU363037, ECO:0000256|SAAS:SAAS00571432}.
Protein families: Class-I aminoacyl-tRNA synthetase family
Coiled coil:
Domain [FT]: DOMAIN 24 332 tRNA-synt_1c. {ECO:0000259|Pfam:PF00749}.; DOMAIN 335 521 tRNA-synt_1c_C. {ECO:0000259|Pfam:PF03950}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NHW4
MEROPS:
EnsemblBacteria KO: ABX81944
UniPathway: K01886
CDD:
Gene3D:
HAMAP: 1.10.1160.10;2.40.240.10;3.40.50.620
InterPro:
PANTHER: IPR001412;IPR004514;IPR000924;IPR020061;IPR020058;IPR020059;IPR020056;IPR011035;IPR014729
PIRSF:
PRINTS:
PROSITE: PR00987
Pfam: PS00178
ProDom: PF00749;PF03950
SMART:
SUPFAM:
TIGRFAMs: SSF50715

1417402-1419031(-)

>nucleotide sequence
TTATTTATAACTTTTCTTAAGCGCTACAATTTCATTAAATATGTATTTATTATCGTTATT
GTAGTAACAGTTGAAATATCCATTTCTAATGAATTGGAATTTTTCTTCATGTAATACATC
TTTTAAGCTACCTTCAATAAAACCTTGTTTTACTGCTAAGGATTCTGTGTTAAATCTTTC
TTCTAATGGTAGTGAACTATCATTTTTAAGTAGTTGACCAAAGAAGTTAAAAGTTGCAGG
AATTGCTGTTGTTGCTTCTACAAAATGAATGGTCCCATCAGGTTTTCTTTCACTAAAACC
AGAACCTGATAATGTCGCTACATCATAAGTTGCAAGTATTTCTGTAATATTACCTTCACT
ATCTTTAACTACATCATTTGCTTGAATAAAGTATGTATGGAATAATCTAACTTCTCTACC
TAAAGATAGACGTTTGTACTTCTTATCAGGTCTTTCTTCTAAGAAGTCTTCTCTATCAAT
ATAGATGTGTTTAGAAAATGCTATTTTTCTGCTACCTAGTGATTCATTTTCACTGTGGAA
CGGTACATCAAAATATTCAATTTTGTCTTCTGGATAGTTTGTAATTGTAACTTTAATCGG
ATCAATGACTGCAAATGCACGTTTAGCACGCATATTCAAATCATCTCTAACAAATGATTC
AAGCATGTCCAGTTCGACTTCACTATTTACTTTACCTAATCCAGTTGCCAAAATAAACGC
TCTAATAGCTTCTTTGGTATAACCTTTTTTACGTAAACCAGAAAGTGTTGGCATTCTAGG
ATCATCCCAACCAGTTACTAGTTTAGAATCTACAAGTTGTTTTAAATATCTTTTTGACAT
GACTGTATTTTCAATACCTAAACGTCCAAACTCGATTTGTCTAGGAACTAAAGGCATTTC
AGTTTCTTTAACAACCCAGTCATATAATGGTCTATGGTCTTCAAACTCTAAAGAACATAA
AGAGTGTGTAATACCCTCAATGGCATCCTCAATCGGATGAGCATAGTCATACATAGGATA
AATCTTCCATTTATCTTTAGTATTATGATGTGTTGCAAAATTGATTCTGTATAAAACAGG
ATCACGCATATTCATGTTTGAACTTGTCATATCAATTTTTGCACGAAGTACTTTGGAACC
TTCTGGATATTTTCCTTCTTCCATTTCTTCAAATAATTTCAAGTTTTCTTCAACAGTTCT
ATTTCTATAAGGAGACTCAATACCCGGTGTGACAACATCGCCTCTTGTTTTAGATATTTC
TTCAGCAGTTTGATCATCTACGTAAGCTAAACCTTTTTTAATTAGTAACTTAGCACGTTC
AAACATTTCTGTAAAATAATCACTTGCAAAATAAATAGCTGAAGGTTCATAACCTAACCA
TCTAACATCACGTTCGATTGCTTCTACATATATCGAATCTTCCTTAGATGGATTCGTATC
ATCATATCTAAGATTTGTTTTTCCGTTAAACACTTTAGCGAGTTCAAAGTTAGTAATAAT
TGCTCTAGCATGACCAATATGTAAAAAACCATTTGGTTCTGGCGGAAAGCGTGTGATAAT
CTCTTTATGTTTGCCCGTTTCTAAATCATTTTCCATAATTGTTTTTATAAAATTTGATTG
ATTTTCCAT

>protein sequence
MENQSNFIKTIMENDLETGKHKEIITRFPPEPNGFLHIGHARAIITNFELAKVFNGKTNL
RYDDTNPSKEDSIYVEAIERDVRWLGYEPSAIYFASDYFTEMFERAKLLIKKGLAYVDDQ
TAEEISKTRGDVVTPGIESPYRNRTVEENLKLFEEMEEGKYPEGSKVLRAKIDMTSSNMN
MRDPVLYRINFATHHNTKDKWKIYPMYDYAHPIEDAIEGITHSLCSLEFEDHRPLYDWVV
KETEMPLVPRQIEFGRLGIENTVMSKRYLKQLVDSKLVTGWDDPRMPTLSGLRKKGYTKE
AIRAFILATGLGKVNSEVELDMLESFVRDDLNMRAKRAFAVIDPIKVTITNYPEDKIEYF
DVPFHSENESLGSRKIAFSKHIYIDREDFLEERPDKKYKRLSLGREVRLFHTYFIQANDV
VKDSEGNITEILATYDVATLSGSGFSERKPDGTIHFVEATTAIPATFNFFGQLLKNDSSL
PLEERFNTESLAVKQGFIEGSLKDVLHEEKFQFIRNGYFNCYYNNDNKYIFNEIVALKKS
YK