ACL_RS06900

Uniprot: A9NE26
Description: fructose-1,6-bisphosphate aldolase, class II
EC number: 1.1.-.-
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor: COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000256|SAAS:SAAS00613810};
Enzyme regulation:
Function [CC]:
Pathway:
Active site: ACT_SITE 84 84 Proton donor. {ECO:0000256|PIRSR:PIRSR001359-1}.
Binding site: BINDING 178 178 Dihydroxyacetone phosphate; via amide nitrogen. {ECO:0000256|PIRSR:PIRSR001359-2}.
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary):
Gene names (synonym):
Mass: 30,410
Subunit structure [CC]:
Gene ontology (GO): fructose-bisphosphate aldolase activity [GO:0004332]; oxidoreductase activity [GO:0016491]; zinc ion binding [GO:0008270]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; glycolytic process [GO:0006096]
Gene ontology IDs: GO:0004332; GO:0006096; GO:0008270; GO:0016491; GO:0030388
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the class II fructose-bisphosphate aldolase family. {ECO:0000256|SAAS:SAAS00591215}.
Protein families: Class II fructose-bisphosphate aldolase family
Coiled coil:
Domain [FT]:
Motif:
Region: REGION 208 210 Dihydroxyacetone phosphate binding. {ECO:0000256|PIRSR:PIRSR001359-2}.; REGION 229 232 Dihydroxyacetone phosphate binding. {ECO:0000256|PIRSR:PIRSR001359-2}.
EMBL: CP000896
ProteinModelPortal: A9NE26
MEROPS:
EnsemblBacteria KO: ABX81986
UniPathway: K01624
CDD:
Gene3D:
HAMAP: 3.20.20.70
InterPro:
PANTHER: IPR013785;IPR011289;IPR000771
PIRSF:
PRINTS: PIRSF001359
PROSITE:
Pfam: PS00602;PS00806
ProDom: PF01116
SMART:
SUPFAM:
TIGRFAMs:

1455015-1455879(-)

>nucleotide sequence
TTAAGCTTTATTTACTGAACCAAACATTGTTAATTTATCTTTAATAACTTGTTTCATTGC
TACATAACCAGGATTTAATAATTTTCTTGGGTCAAATCCTTTAGATTCTAGGTCTTTACC
TTCTTCAATGTATTTTCTAGTTGCAGCAGCAAATGCTAATTGTAACTCAGTGTTTACGTT
GATTTTTGCAATACCTAATGAAATTGCTTTAGTAATTTGGTCTGCAGGAATACCTGTACC
ACCATGTAATACTAAAGGTACACCATTTGTAACTTCACTTACAGTTTTTAATACGCCAAA
GTCTAAACCTTTCCAGTTTGCTGGGTATTTACCATGAATATTACCAATACCAGCAGCGAA
TAGATCTACACCAGTAGCTGCAATAATACGGCATTCTTCTGGATCAGCTAATTCACCTGT
ACCAACAACACCGTCTTCTTCCCCACCAATTGAACCCACTTCAGCTTCTACAGATACACC
AACAGCGTGTGCAACTGCTACAACTTCTTGCGTTTTCTTTAAGTTTTCTTCAAATGGATA
GTGTGAACCATCAAACATTACTGAAGTAAAACCAGCGCGGATTGCTTTAAAAGCACCTTC
ATAAGTACCATGGTCTAGATGAACTGCAACTGGAACACTAATGTTCATTGCTTTGTCTAA
TGTAGATACCATAGCCATAACGTTTTCATAACCACCCATGTATTTAGCTGCACCTTCTGA
TACACCTAAAATCACTGGTGATTTTAATTCTTCAACAGTAGATAATACTGCTTTAATCCA
TTCAAGGTTGTTGATGTTGATTTGTGCAACAGCATAACCTTCAGCCTTAGCTTTTTGTAA
CATTTCTTTTGCGGAAACTAACAT

>protein sequence
MLVSAKEMLQKAKAEGYAVAQININNLEWIKAVLSTVEELKSPVILGVSEGAAKYMGGYE
NVMAMVSTLDKAMNISVPVAVHLDHGTYEGAFKAIRAGFTSVMFDGSHYPFEENLKKTQE
VVAVAHAVGVSVEAEVGSIGGEEDGVVGTGELADPEECRIIAATGVDLFAAGIGNIHGKY
PANWKGLDFGVLKTVSEVTNGVPLVLHGGTGIPADQITKAISLGIAKINVNTELQLAFAA
ATRKYIEEGKDLESKGFDPRKLLNPGYVAMKQVIKDKLTMFGSVNKA